Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
ANXIOLYTIC AND MOTOR COORDINATION ACTIVITY OF HUPERZINE-A IN RATS
The aim of the present study was to evaluate the anxiolytic effects and motor coordination activity of Huperzine-A in rats. Wistar rats were treated orally with Huperzine-A (0.5, 1, 2 & 4 mg/kg) and diazepam (2 mg/kg p.o) as a standard anxiolytic drug then exposed to Elevated plus Maze (EPM) and Light Dark Box (LDB). The effects of the Huperzine-A on motor coordination were evaluated by actoph...
6834
2212
ORAL EXTENDED RELEASE DRY SUSPENSION OF PARACETAMOL LOADED MICROSPHERES
Background: A novel reconstitutable suspension of Paracetamol loaded microspheres was prepared using ethyl cellulose as a release controlling polymer and by solvent evaporation technique for the relief of osteo-arthritic pain. Objective: The formulation was developed to enhance patient compliance of population suffering from dysphagia or have difficulty in swallowing oral solid dosage forms like t...
6757
2367
EFFECT OF HIGH LIPID DIET IN SHRINKING THE AMPICILLIN-INDUCED NEUROTOXICITY IN RAT PUPS, INTER-RELATED TO AUTISM ETIOLOGY
Improper diet can affects the brain and can increase the risk for mental disorders and neurodegenerative diseases like autism. Dietary modification can sometime be helpful to children with autism. The present study examined the effects of a high lipid diet on orally administered ampicillin -induced neurotoxic rats and compared with propionic acid models of autism. Forty young male western albino r...
6463
1556
COMPARITIVE EFFECTS OF HORMONAL AND NON HORMONAL CONTRACEPTIVES ON FASTING BLOOD SUGAR LEVELS
The objective of the current study was to differentiate contraceptives for their effects on carbohydrate metabolism. This is a cross sectional design that was conducted in different clinical settings of urban population who belong to low socio economic status by convenience sampling method. Females representing fertile age ranging from 26 to 32 and maintained on different types of hormonal and non...
3878
1391
IN VITRO ANTIOXIDANT STUDIES ON COLONIAL ASCIDIANS EUDISTOMA VIRIDE AND DIDEMNUM PSAMMATHODES
Ascidians are rich source of novel bioactive agents as potential source of therapeutic drugs. Evaluation of antioxidant potential of ascidians, Eudistoma viride and Didemnum psammathodes extracts was undertaken. In DPPH radical scavenging assay E. viride II showed 34% to 93% scavenging activity and D. psammathodes II showed 45% to 96% scavenging activity in different ascidian concentrations. In re...
3712
2016
RESEALED ERYTHROCYTES: A NOVEL AND PROMISING DRUG CARRIER
Targeted drug delivery, known as smart drug delivery focuses on targeting the medicaments by increasing the residence time and the concentration of drug at the target site of the body (organs, cells, tissues) thus improving the efficacy of treatment and reducing the side effects. Various carriers that can be used in this type of delivery are liposomes, nanoshells, erythrosomes and resealed erythro...
6280
2146
PRELIMINARY PHYTOCHEMICAL SCREENING AND GC MS ANALYSIS OF CHLOROFORM EXTRACT OF KANDELIA CANDEL (L.) DRUCE
The aim of the present study is to screen the phytochemicals present in the leaf extract of Kandelia candel and further analysis of the bioactive components present in it by Gas chromatography - Mass spectrometry (GC-MS) analysis. Carbohydrates, proteins, amino acids, Saponins, flavonoids, terpenoids, glycosides, tannins, alkaloids, and phenols were present in the sample. The percentage yield of p...
3812
1763
ANTIMICROBIAL ACTIVITY OF METHANOLIC EXTRACT OF BARK OF PRUNUS CORNUTA
Prunus cornuta (family Rosaceae) commonly known as ‘Himalayan Bird Cherry’, is a deciduous tree growing to 15 m (49ft 3in) at elevations of 2100-3500 meters. It is hardy to zone (Uttarakhand) 5. It is in flower in May, and the seeds ripen from July to October. The flowers are hermaphrodite and are pollinated by insects and birds. It can grow in semi-shade (light woodland) or no shade. It prefe...
4502
1821
MICROWAVE ASSISTED SYNTHESIS, CHARACTERIZATION, MOLECULAR DOCKING AND ANTIMICROBIAL EVALUATION OF 4-NITROCINNAMIDE ANALOGUES
A series of novel 2-Benzamido-3-(4-nitrophenyl)-N’-(substituted) benzylidene-acrylohydrazide (4a-l) analogues were designed by incorporating the few pharmacophoric fragments to enhance the activity profile of molecules. Title compounds were synthesized by the microwave irradiation of α-Benzamido-(4-nitro)-cinnamahydrazide (3) reveals with aromatic/ heteroaromatic aldehydes under acidic conditio...
3638
1823
ROLE OF EMBLICA OFFICINALIS IN MITIGATING THE SULPHUR DIOXIDE INDUCED TOXICITY IN RATTUS NORVEGICUS (BERKENHOUT)
SO2 is considered as one of the most poisonous and irritant gas because it alters the physiology, biochemistry and behaviour of the living individuals. In the present investigation the effect of oral administration of Emblica officinalis on serum electrolyte in SO2 exposed albino rats. The thirty albino rats were grouped in three sets - control set (1) were kept in control conditions, while, rats ...
3407
1510