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CADMIUM MONITORING AMONG SOME PLANT AND VEGETABLE SPECIES IN SINGRAULI REGION OF MADHYA PRADESH
Thermal power plants produce enormous quantity of pollutants such as fly ash as a by - product of combustion of coal or any pulverized fuel at higher temperature. Industrial effluents contain several heavy metals including cadmium distrusted the metabolic process of living organism due to easily dispersion and mobilization in environment. The eatables and applicable potential plants and vegetables...
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PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIOXIDANT ACTIVITY ANALYSIS IN LEAF EXTRACT OF WATER APPLE [SYZYGIUM AQUEUM (BURM. F) ALSTON]
Syzygium aqueum is a well-known edible fruit-bearing plant species. The tribal people in Malaysia used different parts of the plant to cure various ailments. The previous studies on phytochemical evaluation of S. aqueum are very limited. The present study aims to conduct a detailed investigation of phytochemicals present in the leaves of S. aqueum and also its potential use as an effective antioxi...
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PELLETIZATION OF LAMOTRIGINE SOLID DISPERSION FOR IMPROVED SOLUBILIZATION
Poorly solubility in water of many newly developed high-potential drugs is an obstacle in formulation development. The aim of this study was to increase the solubility of Lamotrigine which is a poorly soluble drug and comes under BCS class-II by using solid dispersion technique. Lamotrigine, PEG 4000 and PVPK-30 solid dispersion was prepared by solvent evaporation method and the formulation was ch...
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DESIGN AND CHARACTERIZATION OF PULSATILE DRUG DELIVERY SYSTEM OF LERCANIDIPINE
The purpose of the present investigation is to formulate and evaluate Lercanidipine pulsatile drug delivery system by press coating method. The inner core tablets were prepared by using direct compression method by using cross-carmellose sodium (Ac-Di-Sol), sodium starch glycolate, crospovidone as super disintegrants. The drug polymer interaction was investigated by FTIR and their results directed...
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DOXORUBICIN AND CHLOROQUINE: A COMBINATION THERAPY TO OVERCOME THE MULTI DRUG RESISTANCE IN CANCER – A REVIEW
Cancer is a genetic disorder that can happen to anybody; anytime. The treatment, where one or more chemotherapeutic agents (anti-cancer drugs) are used either to treat the cancer patients (curative intent with one or combination of anti-cancer drugs) or to prolong the life and to reduce the symptoms in cancer patients is known as Chemotherapy. But nowadays it is observed that when these chemothera...
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DESIGN AND EVALUATION OF DILTIAZEM HYDROCHLORIDE LOADED BUCCAL PATCH
The purpose of this study was to develop and optimise the formulation of mucoadhesive patches of Diltiazem hydrochloride using chitosan as base matrix. The patches were prepared by solvent casting method. PVP (K30) and propylene glycol were introduced into the patches formulae to improve the filming properties. The patches were found to be smooth in appearance, uniform in thickness, weight, and ...
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SYNTHESIS, EXPERIMENTAL STUDIES OF THE ANTIMICROBIAL POTENTIAL OF SOME NOVEL 1, 5- BENZO THIAZEPINE DERIVATIVES
Optically active 1, 5- benzothiazepines belong to the well known benzothiazepine type substances. Some of them possess important bioactivities. In this article, optically active 2, 3-dihydro-1, 5-benzothiazepine derivatives are synthesized by the reaction of new α-β unsaturated carbonyl compounds with 2-aminothiophenol under mild conditions in the presence of silver sulphate in acetonitrile in s...
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DEVELOPMENT AND CHRACTERIZATION OF SELF ASSEMBELED NANOPARTICLES: A REVIEW
Various types of lipid based vesicular systems have been developed in controlled and targeted drug delivery. Self assembled nanoparticles (SAN) has advantages over traditional colloidal vesicular systems and also avoids some of their major disadvantages. SAN made of solid lipids are submicron colloidal carriers (50-1000nm). These consist of a solid hydrophobic core having a monolayer of phospholip...
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EVALUATION OF EFFICACY AND SAFETY OF GEMIFLOXACIN IN CHRONIC BRONCHITIS PATIENTS
The study aimed to assess the efficacy and safety of Amoxicillin/Clavulanate 625 mg and Amoxicillin/Clavulanate 1 gram in chronic bronchitis patients. Chronic bronchitis, a type of COPD defined by a productive cough that lasts for 3 months or more for at least 2 years, other symptoms include wheezing and breathlessness, upon exertion. It is caused by recurring irritation to the epithelium of bronc...
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CYTOTOXIC ACTIVITY OF CROCUS PALLASII SUBSP. HAUSSKNECHTII IN HUMAN CANCER CELL LINES
Crocus pallasii subsp. haussknechtii grows in the west of Iran where local people consume the corm. It belongs to a saffron family (Iridaceae), which has shown several biological activities including cytotoxic and anti-angiogenesis properties. The corm (the nut and the surrounding fibers) and aerial parts of the species have shown anti-angiogenesis properties in HUV-EC-C cells previously; in the p...
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