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THERMAL AND STRUCTURAL PROPERTIES OF IRRADIATED SILVER/POLY (VINYL ALCOHOL) (Ag/PVA) NANOCOMPOSITES USING ARGON ION BEAM
Structural and thermal properties of silver/poly(vinyl alcohol) (Ag/PVA) nanocomposites has been investigated as a function of Argon ion beam fluence. The XRD patterns (X-ray diffraction) showed the formation of the Ag/PVA in polymer structure and phase analysis with different sizes as a function of either ion beam fluence or Ag+ ion molar concentrations. The kinetic parameters for the thermal s...
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SYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL ACTIVITY OF 2-HYDROXY 3-NITRO-5-METHYL-N-(SUBSTITUTED PHENYL) CHALCONE IMINES
Chalcones and its derivatives show various biological activities. The present study deals with the synthesis of series of 2-hydroxy-3-nitro-5-methyl–N-substituted phenyl chalcone imines from 2-hydroxy-3-nitro-5-methylphenyl chalcone and different substituted aromatic animes in ethanol in presence of 2, 3 drops of Conc. H2SO4. Structures of synthesized compounds have been established by spectral ...
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SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 2-SUBSTITUTED BENZOTHIAZOLE DITHIOMIDOCARBONATE DERIVATIVES
A series of novel 2- substituted benzothiazole dithiomidocarbonate derivatives were synthesized by the reaction of 2-amino benzothiazole with various halides. The test compounds were screened for their antimicrobial activity (antibacterial and antifungal) by disc diffusion method and the results of the microbial activity indicates that the test compounds exhibited varying degree of antimicrobial a...
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FORMULATION AND EVALUATION OF STOMACH SPECIFIC FLOATING IN-SITU GEL OF CLARITHROMYCIN
Floating drug delivery system comes with the advantage of sustained release of drugs over a prolonged period of time thereby maximizing the oral absorption of drugs with narrow absorption window, it overcomes the challenges of conventional oral drug delivery system. The aim of the present work was to develop a novel floating in-situ gelling system for sustained drug delivery of Clarithromycin for ...
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ENDOCRINE DISRUPTING CHEMICALSAND MALE REPRODUCTION: A SPECIAL FOCUS ON ANTITHYROID DRUGS AND RECUPERATIVE EFFECTS OF Α-LIPOIC ACID
Male reproduction is controlled and coordinated by endocrine factors and therefore, even minute changes can able to interfere with the male fertility. Accumulation of data have shown that the humans are exposed to chemicals that can able to interfere with endocrine factors. Interestingly, published reports have shown that the continuous exposure to such chemicals occurs mainly due to their wide us...
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RIFAMPICIN AND ISONIAZID MICROCAPSULES FOR TREATMENT OF TUBERCULOSIS
Rifampicin and Isoniazid microcapsules were prepared by phase seperation coacervation method for inclusion in suspension formulations. Ethyl cellulose was used as the coating material for microencapsulation. Developed microcapsules were characterized for visual appearance, photomicrography, sieve analysis, drug content, bulk density, ethyl cellulose content and drug release studies. Microcapsules ...
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ANTIBACTERIAL EVALUATION OF SYNTHESIZED METHYL SEMICARBAZONE DERIVATIVES
In the present study a series of chalcone- semicarbazones was synthesized and evaluated for their antibacterial activity by paper disk diffusion method. Based on the results of an antibacterial study, compound 28 was the most active compound against gram negative bacteria. Synthesized compounds were inactive against gram positive bacteria. It was found that chloro- substitution in the aldehydic mo...
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ROLE OF DEFERASIROX, AN ORAL IRON CHELATOR IN PREVENTION OF ISCHEMIC REPERFUSION MYOCARDIAL INJURY IN ALBINO RABBITS
An experimental study was carried out after getting approval from institustional animal ethical committee to study the role of oral iron chelator, deferasirox in prevention of myocardial ischemic reperfusion injury in albino rabbits. Albino Rabbits of either sex were divided into two groups control (n=5) and test group (n=5), receiving deferasirox. Experiments were done using isolated heart perf...
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ISOLATION OF ACAULOSPORA SPECIES FROM JATROPHA CURCAS L AND PONGAMIA PINNATA PIERRE
Jatropha curcas L. and P. pinnata Pierre is gaining importance as biodiesel crop in India. Jatropha curcas L. a member of the family Euphorbiacea and Pongamia pinnata, a member of the family Leguminoseae. A study was conducted to identify common arbuscular mycorrhizal fungi present in its rhizosphere from different regions of India viz., Jodhpur (Rajasthan), Hissar (Haryana), Jhansi and Lalitpur (...
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A COMPARATIVE EVALUATION OF LASER ASSISTED & CONVENTIONAL OPEN FLAP SURGICAL DEBRIDEMENT PROCEDURE IN PATIENTS WITH CHRONIC PERIODONTITIS – A CLINICAL AND MICROBIOLOGICAL STUDY- A PILOT PROJECT
Background and Objectives: Current research suggests several advantages of the adjunctive use of lasers in periodontal therapy. The aim of this study was to assess and evaluate the comparative therapeutic effects of laser-assisted and conventional open flap debridement procedures. Materials and Methods: 30 sites in 15 patients (9 males and 6 females), age range (25-50 yrs) with chronic periodontit...
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