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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

IJPSR is indexed with Embase

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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8.

PHYTOCHEMICAL AND BIOLOGICAL EVALUATION OF VITEX NEGUNDO LINN: A REVIEW

Vitex negundo Linn. belong to family Verbenaceae. It is an important medicinal plant.Literaturesurvey of V. negundo revealed the presence of  different classes of natural products including essential oil,triterpenes, diterpenes, sesquiterpenes, lignan, flavonoids,flavones glycosides, iridoid glycosides, and stilbene derivative. The plant is traditionally reported for its use for the treatment of ...

Zahoor Ullah*, Riaz Ullah , Azhar-ul-Haq Ali Shah , Ijaz Ahmad and Sajjad Haider

Department of Chemical Engineering, College of Engineering, King Saud University, P.O BOX 800, Riyadh 11421, Saudi Arabia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(8).2421-31

2421-2431

9918

3490

25

2.

COUNTERFEIT (FAKE) DRUGS & NEW TECHNOLOGIES TO IDENTIFY IT IN INDIA

A counterfeit medicine is one which is deliberately and fraudulently mislabeled with respect to identity or source. Counterfeiting apply to both branded and generic product which include products with the wrong ingredients, without active ingredients, with insufficient active ingredients. According to WHO, 25% of medicines consumed in poor countries could be counterfeit or below standard.An estima...

P. Gupta*, K. Singhal and A. Pandey

Department of Pharmaceutical Sciences (FAMS), Gurukul Kangri University, Haridwar-249404, Uttarakhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(11).4057-64

4057-4064

9907

2260

23

2.

NASAL DRUG DELIVERY- AN OVERVIEW

Over the past few decades the nasal route has gained widespread interest as a promising and an alternative route to oral and parenteral drug delivery. The nasal mucosa being highly vascularized and permeable provides a rapid onset of therapeutic action. It is a convenient, compliant and needleless mode of drug delivery suitable for the treatment of both acute and chronic diseases. In addition, nas...

Jyoti Mundlia , Mukesh Kumar and Amardeep

Assistant Professor College of Pharmacy , PGIMS, Rohtak, Haryana, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(3).951-60

951-960

9897

3204

21

38.

MACROSCOPIC AND MICROSCOPIC EVALUATION OF ABRUS PRECATORIUS L. (GUNJA), SEEDS

The excessive exploitation of medicinal plants during recent years raises the issues regarding their quality, safety and efficacy. In this respect, there has been a rapid increase in the standardization of medicinal plants with therapeutic potential. In spite of the new techniques, identification and evaluation of plant drugs pharmacognostic study is more cheap and reliable. Abrus precatorius L. o...

S. Tabasum *, S. Khare and K. Jain

Department of Botany, Government Science and Commerce College Benazeer, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(6).2631-35

2631-2635

9887

2469

11

3.

PHYTOTHERAPY IN THE TREATMENT OF ARTHRITIS: A REVIEW

As the conventional treatment is associated with large number of side effects, herbal treatment is gaining popularity particularly in the treatment of chronic disease like jaundice, vitiligo, rheumatoid arthritis, asthma etc. Herbal treatment has been identified as safe and effective in treating such disease. The aim of this study was to review systematically the evidences and effectiveness of her...

Jyotsna Choubey*, Ashish Patel and M.K. Verma

Sub-DIC Bioinformatics, National Institute of Technology Raipur, Raipur, Chhattisgarh, India

DOI: 10.13040/IJPSR.0975-8232.4(8).2853-65

2853-2865

9866

2728

14

14.

ANALYTICAL METHOD VALIDATION FOR DETERMINATION OF RELATED SUBSTANCES OF DEXMEDETOMIDINE (IMPURITY-1) IN DEXMEDETOMIDINE HYDROCHLORIDE INJECTION

Dexmedetomidine, approved by the Food and Drug Administration (FDA) in 1999 as a sedative for use in the intensive care unit, is a potent and highly selective α2-adrenoceptor agonist with significant sedative, analgesic and anxiolytic effects mostly used in the intensive care units. This article describes validation for determination of related substances of dexmedetomidine (impurity-1) in dexmed...

Muralee Krishna, Meghana Nadre, Anirudhha Sherikar and Ranjith Reddy *

Glenmark pharmaceutical Limited, Pithampur, Madhya Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(12).5070-76

5070-76

9865

4676

2

37.

COMPARATIVE QUALITY EVALUATION OF PARACETAMOL TABLET MARKETED IN SOMALI REGION OF ETHIOPIA.

The safety and efficacy of a pharmaceutical dosage form can be guaranteed when its quality is reliable. The efficacy of pharmaceutical dosage forms generally depends on their formulation properties, and manufacturing methods, hence it is likely that the quality of dosage form may vary. The aim was to evaluate the quality of paracetamol tablet marketed in Somali region of Ethiopia. The study was ex...

Samuel Belay Sahle , Amene Tesfaye Ayane , Nasir Tajure Wabe*

Lecturer, Clinical Pharmacy Unit, Pharmacy Department, College of Public Health and Medical Science, Jimma University, P.O.BOX 251 1480, Jimma, Ethiopia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(2).545-50

545-550

9864

2791

43

16.

NANOSPONGE LOADED HYDROGEL OF CEPHALEXIN FOR TOPICAL DELIVERY

Cephalexin is a first generation cephalosporin antibiotic which is used for the treatment of skin and soft tissue infection, urinary tract infection and diabetic foot infection. Since cephalexin is not available as topical formulation, cephalexin was formulated into nanosponge loaded hydrogel as it can enhance skin permeation. Nanosponges of cephalexin were prepared using hydroxyl ethyl cellulose ...

G. Jilsha and Vidya Viswanad*

Department of Pharmaceutics, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham University, AIMS Healthcare Campus, Ponekkara P.O., Kochi, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.6(7).2781-89

2781-89

9850

3077

39

11.

3D-QSAR AND CONTOUR MAP ANALYSIS OF TARIQUIDAR ANALOGUES AS MULTIDRUG RESISTANCE PROTEIN-1 (MRP1) INHIBITORS

One of the major obstacles to the successful chemotherapy towards several cancers is multidrug resistance of human cancer cells to anti-cancer drugs. An important contributor to multidrug resistance is the human multidrug resistance protein-1 transporter (MRP1), which is an efflux pump of the ABC (ATP binding cassette) superfamily. Thus, highly efficacious, third generation MRP1 inhibitors, like t...

P, Kakarla, M. Inupakutika, A. R. Devireddy, S. K. Gunda, T. M. Willmon, Ranjana KC , U. Shrestha, I. Ranaweera, A. J. Hernandez, S. Barr, And M. F. Varela٭

Department of Biology, Eastern New Mexico University, Station 33, Portales, NM, 88130,USA

DOI: 10.13040/IJPSR.0975-8232.7(2).554-72

554-72

9832

2513

26

9.

BIOACTIVE COMPOUNDS FROM MICROALGAE AND CYANOBACTERIA: UTILITY AND APPLICATIONS

Microalgae and Cyanobacteria (blue-green algae) are photosynthetic prokaryotes used as food by humans. They have gained a lot of attention in recent years because of their potential applications in biotechnology. They have also been recognized as an excellent source of vitamins and proteins and as such are found in health food stores throughout the world. They are reported to be a source of fine c...

I. Priyadarshani and B. Rath*

Department of Biotechnology, North Orissa University, Sriram Chandra Vihar, Takatpur, Baripada-757003, Odisha, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(11).4123-30

4123-4130

9831

3651

50