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PHARMACOGNOSTICAL, PHYTOCHEMICAL AND PHARMACOLOGICAL REVIEW ON CLITORIA TERNATEA FOR ANTIASTHMATIC ACTIVITY
In recent times, focus on plant research has increased all over the world and a large body of evidence has collected to show immense potential of medicinal plants used in various traditional systems. Use of plant based drugs and chemicals for curing various ailments and personal adornment is as old as human civilization Clitoria ternatea is used for curing various diseases and symptoms. Clitoria t...
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EVALUATION OF α – AMYLASE INHIBITORY ACTIVITY OF SOME CLINICALLY USED DRUGS
Finding out the alternative uses of the clinically proven and time tested drugs can be one of the best options for drug discovery research. In view of this the present study was carried out to evaluate α-amylase inhibitory activity of the some of the commonly used drugs. The drugs were procured as gift samples from pharmaceutical companies and were evaluated for in-vitro α-amylase inhibitory act...
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A COMPLETE GUIDE ON THE PHARMACOLOGIC AND PHARMACOTHERAPEUTIC ASPECTS OF CALCIUM CHANNEL BLOCKERS: AN EXTENSIVE REVIEW
The calcium channel blockers, a diverse group of cardiovascular drugs, exert their action by inhibiting the L-type calcium channels and cause vasodilatation in the heart and the smooth muscles. They also block the action potential at the SA and AV node, thus prolonging the duration of the action potential (Verapamil and Diltiazem). Although, the calcium channel blockers have the same anti-hyperten...
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2021
LIQUISOLID TECHNIQUE: A REVIEW
Dissolution of drug and its release from the dosage form have basic impact on bioavailability. Bioavailability depends on solubility of drug. Solubility is major challenge for the pharmaceutical industry with the developments of new pharmaceutical products. There are several approaches for solubility enhancement which includes micronization, Nanonisation, use of salt forms, use of surfactant, soli...
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FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF TELMISARTAN
The patients with sudden increase blood pressure have markedly reduced function ability and extremely restless, in such cases rapid onset of action is of prime importance. So the patients would be benefited from acute treatment by using Fast dissolving drug delivery system. Telmisartan is an Anti-hypertensive drug which is insoluble in water; hence the drug may be slowly or incompletely dissolves ...
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SCIENTIFIC CONCEPTS OF POLYMERASE CHAIN REACTION (PCR)
This paper is specifically designed to explain the important scientific points of Polymerase Chain Reaction (PCR) technology in forensic science and molecular biology. Scientific procedures presented in the paper are complex, simple were specifically designed to better explain and reinforce the key concepts of PCR. The PCR is a laboratory technique for amplifying a specific sequence of a minute am...
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POST APPROVAL CHANGES IN BIOLOGICAL PRODUCTS
The post approval changes are the changes made to biological products that have received an approval and to provide the data to support a change which would be considered sufficient to allow a determination of the impact of the change on the quality of the approved products as it relates to safety, efficacy and/or effective use of the products. After the approval of NDA or ANDA, the applicant may ...
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2021
STRATEGIES FOR ENHANCEMENT OF BIOAVAILABILITY OF MEDICINAL AGENTS WITH NATURAL PRODUCTS
In Advances drug design technologies, a large no of drug molecules are being introduced in every year but many of these molecules have problems like their solubility, stability, bioavailability and its long lasting side effects. Low bioavailability is one of the serious but curable problems in case of the drug molecule. Low bioavailability happens because a lot of molecules unable to permeation th...
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FORMULATION AND EVALUATION OF TRANSDERMAL GEL OF LORNOXICAM AND ITS DELIVERY BY PASSIVE AND INOTOPHORESIS METHOD: A COMPARATIVE STUDY
The objective of present study was to develop Lornoxicam transdermal gel and its iontophoretic delivery to enhance its permeation for systemic effect and to avoid its side effects. Lornoxicam is a COX-1 and COX-2 inhibitor used in the treatment of inflammation, pain, edema and rheumatoid arthritis. Transdermal gel of Lornoxicam was formulated using triethanolamine as solvent, carbopol 934P as gel ...
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PHYTOCHEMICAL AND BIOLOGICAL EVALUATION OF VITEX NEGUNDO LINN: A REVIEW
Vitex negundo Linn. belong to family Verbenaceae. It is an important medicinal plant.Literaturesurvey of V. negundo revealed the presence of different classes of natural products including essential oil,triterpenes, diterpenes, sesquiterpenes, lignan, flavonoids,flavones glycosides, iridoid glycosides, and stilbene derivative. The plant is traditionally reported for its use for the treatment of ...
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