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EVALUATION OF EXTRACTION TECHNIQUES WITH VARIOUS SOLVENTS TO DETERMINE EXTRACTION EFFICIENCY OF SELECTED MEDICINAL PLANTS
Herbal drugs play an important role in health care dynamics especially in developing countries. The key step in isolation of biologically active compounds is extraction, which is expressed as total extractive yield, yields of metabolites of interest or intensity of biological activity. Extraction of phytoconstituents from plant materials has been of tremendous interest and potential. Extractive va...
7948
1950
ANTIMICROBIAL AND TOXICITY STUDY OF DIFFERENT FRACTIONS OF DILLENIA INDICA LINN. BARK EXTRACT
The methanolic extract along with some organic soluble fractions of the bark of Dillenia indica Linn. were tested against four Gram-positive and seven Gram-negative bacteria and against three pathogenic fungi. n-Hexane and dichloromethane fractions showed remarkable activities against all the tested bacteria but n-Hexane fraction showed highest activity against Shigella dysenteriae and its zone of...
7940
1375
INVESTIGATING THE EFFECT OF MOLECULAR WEIGHT OF POLYVINYLPYRROLIDONE AND HYDROXYPROPYL METHYL CELLULOSE AS POTENTIAL ANTIPRECIPITANTS ON SUPERSATURATED DRUG SOLUTIONS AND FORMULATIONS USING WEAKLY ACIDIC DRUG: INDOMETHACIN
Most of the drug discovered in past decade belongs to biopharmaceutical classification system (BCS) class II. The solubility of these drugs is the limiting factor for oral bioavailability. The drug can be present in solution in a supersaturated state; however, it has a tendency to crystallize out. In this paper, we aim to study the effect of molecular weight of Polyvinylpyrrolidone (PVP) (PVP K12,...
7922
1928
PREPARATION AND IN-VITRO EVALUATION OF DICLOFENAC SODIUM NIOSOMAL FORMULATIONS
Incorporation of drugs into non-ionic surfactant vesicles (niosomes) during their manufacture affords a possible method of achieving controlled release. The aim of this study is to formulate niosomes as carriers for delivery of diclofenac sodium (DCS). Niosomes are prepared with a series of sorbitan monoesters (Span 20, 40, 60, and 80) and sorbitan tri-oleate (Span 85) and co-surfactants of polyox...
7921
2558
PLUMBAGO ZEYLANICA: A PHYTOPHARMACOLOGICAL REVIEW
Ayurveda is time-tested science of treating disease with natural things like plant, animals and minerals. It remains one of the most ancient and yet living traditions practised widely in India, Sri Lanka and other countries and has a sound philosophical and experiential basis. Plumbago zeylanica is commonly known as white chitraka, belongs to family plumbaginaceae. It is distributed as a weed ...
7918
2500
ANTIMICROBIAL POTENTIAL OF EXTRACT FROM LEAVES OF KALANCHOE PINNATA
Herbal medicine refers to the use of any plant's seeds, berries, roots, leaves, bark, or flowers for medicinal purposes. Kalanchoe pinnata is known as herbal medicine that having many special advantages. The objective of the study was to scientifically assess antimicrobial activity of 95% ethanolic, methanolic, 60% methanolic and aqueous extract of leaves from Kalanchoe pinnata on Staphylococcus a...
7909
2461
IN-VITRO ANTIMICROBIAL ACTIVITY OF EDIBLE OILS AGAINST HUMAN PATHOGENS CAUSING SKIN INFECTIONS
In recent years, a large number of oils and their constituents have been investigated for their antimicrobial properties against bacteria and fungi. The present investigation evaluated the antimicrobial potential of edible medicinal oils of Cocos nucifera, Helianthus annus, Brassica juncea, Ricinus communis, Arachis hypogea, Glycine max, Gossypium hirsutum and Sesamum indicum extracted from differ...
7907
2057
BIO-SYNTHESIZED NANO-FORMULATION OF ZINC OXIDE – ALOE VERA AND TO STUDY THEIR CHARACTERIZATION AND ANTIBACTERIAL ACTIVITIES AGAINST MULTIPLE PATHOGENS
Nano-sized ZnO particles of specific morphology were synthesized using the plant leaf extracts of Aloe vera. In modern science Nanotechnology is an ablaze field for the researchers. Nanoparticles having a size of 1-100 nm in one dimension are used significantly concerning medical chemistry, atomic physics and all other known fields. Nanoparticles are used immensely due to its small size, orientati...
7905
1981
CORRELATION OF MINIMUM INHIBITORY CONCENTRATION OF CIPROFLOXACIN TO THE THERAPEUTIC RESPONSE OF PATIENT WITH URINARY TRACT INFECTION CAUSED BY ESCHERICHIA COLI
The choice of an antibiotic depends solely on the identification of the species by determination of the sensitivity characteristics of the microorganism. Along with the determination of sensitivity pattern, understanding the susceptibility pattern of particular strain isolated from patient is equally important. Variation in patient and microorganism is known to be key factor for predicting the out...
7902
1311
AN OVERVIEW ON SOLUBILITY ENHANCEMENT TECHNIQUES FOR POORLY SOLUBLE DRUGS AND SOLID DISPERSION AS AN EMINENT STRATEGIC APPROACH
Solubility is an important parameter to achieve desired concentration of drug in systemic circulation for pharmacological response to be shown. Among all newly discovered chemical entities most of the drugs are lipophillic and fail to reach market due to their poor water solubility. The solubility behavior remains one of the most challenging aspect informational development. Hence various techni...
7899
3048