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CURRENT AND NOVEL TECHNIQUES IN THE OPHTHALMIC DRUG DELIVERY SYSTEMS
For human survival, vision or sight is extremely important. Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. There are both conventional and novel drug deliveries available as topical administration for the treatment of diseases related to the eye. Conventional dosage form includes ophthalmic solutions, suspen...
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RECENT DEVELOPMENT AND ACHIEVEMENTS IN SOLUBILITY AND DISSOLUTION ENHANCEMENT OF ITRACONAZOLE: A REVIEW
A drug should be available in accessible in disintegrated state before producing its therapeutic effect however; in current market more than 40%, drugs are poorly soluble in water. In view of their low aqueous solubility, those new chemical entities fail to reach market in spite of revealing potential pharmacodynamics activities. Poorly aqueous soluble drugs are connected with moderate drug absor...
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CLINICAL AND RADIOGRAPHIC EVALUATION OF PULPAL AND PERIRADICULAR TISSUE
Objective: The aim of the present study was to evaluate the clinical and radiographic aspects of pulpal and periradicular tissue for patient undergoes endodontic treatment. Patient and method: The present study was limited to patients who treated endodontically by postgraduate students of Conservative Department, School of Dentistry/Faculty of Medical Sciences between January 2014 to February 2015...
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FUNCTIONALITY TESTING OF EXCIPIENTS: A REVIEW
The quality of medicines depends not only on the active principles and production processes, but also the performance of the excipients, hence we say’ Excipients are Cindrellas of Formulation’. The traditional concept of the excipient as any component other than the active substance has undergone a substantial evolution from an ‘inert’ and cheap vehicle to an essential constituent of the f...
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SCIENTIFIC CONCEPTS OF POLYMERASE CHAIN REACTION (PCR)
This paper is specifically designed to explain the important scientific points of Polymerase Chain Reaction (PCR) technology in forensic science and molecular biology. Scientific procedures presented in the paper are complex, simple were specifically designed to better explain and reinforce the key concepts of PCR. The PCR is a laboratory technique for amplifying a specific sequence of a minute am...
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF BENZIMIDAZOLE DERIVATIVES
Benzimidazoles are an important class of compounds with a wide spectrum of biological activity ranging from anti-hypertensive, anti-viral, anti-fungal, antitumor and anthelmintic activity. Benzimidazole rings are the most important nitrogen-containing heterocycles, which are widely explored and utilized by the pharmaceutical industry for drug discovery. Due to their special structural features and...
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APPROACHES TO PULMONARY DRUG DELIVERY SYSTEMS
Pulmonary route have been used to treat various respiratory diseases for centuries. Ancient inhalation therapies included the use of leaves from plants, vapors from aromatic plants, balsams, and myrrh. The pulmonary route has gained increasing importance in the recent times due to its unique properties such as a large absorptive area of up to 100m2; extremely thin 0.1 μm – 0.2 μm absorptive mu...
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APPLICATION OF MODERN ELECTROANALYTICAL TECHNIQUES: RECENT TREND IN PHARMACEUTICAL AND DRUG ANALYSIS
The determination of drugs in pharmaceutical preparations and biological fluids is of pivotal importance in the pharmaceutical and medical sciences. Successful analysis requires sensitivities at ppb level or even less in biological fluids with high selectivity and minimal interferences from various artifacts. Till recently, biopharmaceutical analysis relied principally on spectrophotometric assay,...
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A REVIEW ON NATURAL CHALCONES AN UPDATE
Plants are a valuable source of secondary metabolites. Many phytochemicals are obtained from the plant sources that are used as valuable medicinal agents. Chalcones are one of the important secondary metabolites obtained from many edible plants like foods, vegetables, tea, spices and natural foodstuffs. Chalcones considered as obligate intermediated in flavonoid biosynthesis but they do not accumu...
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A COMPREHENSIVE REVIEW ON COSTUS PICTUS D. DON
Costus pictus is rhizomatous medicinal herb, commonly known as “Insulin plant,” well known for its therapeutic properties. Many important and beneficial aspects of C. pictus are reported, which includes anti-diabetic, anti-microbial, anti-cancer, anti-oxidant, anti-fertility, anti-helminthic, diuretic, anti-inflammatory properties. The present review focus on the literature survey based on the...
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