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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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49.

PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL ACTIVITIES WITH RESPECT TO ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF JATROPHA CURCAS FRUIT

Objective: To evaluate the analgesic and anti-inflammatory effects of the methanolic extract of the Jatropha curcas (MEJC) belonging to the family Euphorbiaceae. Materials and Methods: Phytochemical screening was done by standard procedures. Acute toxicity studies were done by using female albino mice weighing 23-35 gm as per OECD 425 guidelines. In the hot plate models for analgesic activity, the...

D. Dasgupta * and M. Rahman

Department of Pharmaceutical Chemistry, Girijananda Chowdhury Institute of Pharmaceutical Science, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.10(11).5211-15

5211-5215

1418

596

20.

A STATISTICAL APPROACH TO DEVELOPMENT OF SUSTAINED RELEASE PRONIOSOMAL MICONAZOLE NITRATE GEL

Miconazole nitrate is a broad-spectrum antifungal agent, and it is used for the treatment of superficial fungal infections. It has low skin permeability. Therefore, the aim of this study was to prepare proniosomal 2% miconazole nitrate sustained release to a treat deep-seated fungal infections. The different batches of proniosomal 2% miconazole nitrate gel were prepared by the conservation phase s...

N. A. Oza * and S. V. Sagar

C. U. Shah College of Pharmacy & Research, Surendranagar, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5508-17

5508-5517

1417

773

59.

NEUROBIOLOGICAL EVALUATION OF DERIVATIVES OF SUBSTITUTED PHENYL-ETHYLAMINE AND ETHYLAMINE

Cognitive functions are mainly categorized into memory, attention, creativity, and intelligence. Cognitive enhancement may be defined as the amplification or extension of core capacities of the mind. Phenylethylamine is an organic compound which is also known as β-phenylethylamine (β-PEA) and is the name of a class of chemicals which shows psychoactive and stimulant effects. It is a trace amine ...

N. Kaur * and J. S. Dua

LBR College of Pharmacy, Golpura, Panchkula, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2462-69

2462-2469

1416

790

46.

THE INFLUENCE OF DIETARY COMPOSITION TO METABOLIC SYNDROME INCIDENCE

Metabolic syndrome is a group of several clinical conditions which is related to the prevalence of another disease such as cardiovascular disease, diabetes mellitus (DM) or increased fasting blood glucose level, visceral obesity, hypertension, etc. The major factor that affects the metabolic syndrome occurrence is diet composition.This research aimed to determine the influence of diet composition ...

W. Aligita *, A. Sumanjaya and I. K. Sukmawati

Department of Pharmacology, Bandung School of Pharmacy, Jl. Soekarno Hatta, Bandung, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.10(10).4782-86

4782-4786

1415

633

11.

ANTICANCER POTENTIAL OF PLUMBAGO ZEYLANICA LINN. AND ITS ISOLATED CONSTITUENT PLUMBAGIN: A REVIEW

Varieties of natural products have been proved as a rich source of phytoconstituents which are reported for a wide range of therapeutic potential. Plumbago zeylanica L. Is one of the herbs which are traditionally used for its therapeutic value. It is reported for several bioactive chemical constituents like naphthoquinones, flavonoids, alkaloids, glycosides, steroids, tri-terpenoids, tannins, fixe...

H. S. Kapare *, S. R. Metkar and S. V. Shirolkar

Dr. D. Y. Patil Unitech Society’s, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.11(10).4859-65

4859-4865

1415

559

27.

EVALUATION OF ANTI-PARKINSON’S ACTIVITY OF CYAMOPSIS TETRAGONOLOBA METHANOL PLANT EXTRACT WITH BEHAVIORAL AND BIOCHEMICAL ANALYSIS

In the present study, we evaluated the Anti-parkinson’s activity of Cyamopsis tetragonoloba methanol plant pod extract by Haloperidol Induced Catalepsy and Tacrine induced vacuous jaw movements for behavioral parameters and in-vivo assays to estimate neurochemical parameters like (GSH, LPO, and SOD). The behavioral analysis performed using Haloperidol Induced Catalepsy produces Parkinson’s dis...

B. Kaur * and J. Saxena

Department of Chemistry, Barkatullah University, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(6).3236-42

3236-3242

1415

621

44.

HPTLC FINGER PRINT PROFILE OF ROOT EXTRACTS OF MARTYNIA ANNUA LINN.

The objective of the present study is to evaluate phytochemical composition and HPTLC finger print profile of medicinally useful plant Martynia annua L. (Martyniaceae) root extracts. The CAMAG HPTLC system was used for the finger print profiling of root extract using the mobile phase chloroform: Methanol (9:1 v/v). The profile showed that the root extract of Martynia annua exhibited several peaks ...

R. K. Gupta * and M. Deogade

Department of Dravyaguna, MGACH & RC, Wardha, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.11(7).3450-56

3450-3456

1414

599

8.

COMPARATIVE STUDY OF THE EFFECTS OF LAURUS NOBILIS AND SYZYGIUM AROMATICUM AQUEOUS EXTRACTS ON URINE VOLUME AND RENAL FUNCTION IN RATS

The purpose of the current study was to investigate the diuretic and renal effect of the aqueous extracts of Laurus nobilis leaves and dried flower buds of Syzygium aromaticum. Four groups of rats were used. Group 1 received distilled water (10 ml/kg BW), group 2 received the aqueous extract of Laurus nobilis (300 mg/kg BW), group 3 received the aqueous extract of Syzygium aromaticum (300 mg/kg BW...

A. Taroq *, M. Bakour, Y E. Atki, F. E. Kamari, I. Aouam, F. Z. Talbi, N. Hammas, B. Lyoussi and A. Abdellaoui

Laboratory of Physiology Pharmacology and Environmental Health, Department of Biology, Faculty of Sciences Dhar Mahraz, University Sidi Mohamed Ben Abdellah, Atlas, Fez, Morocco.

DOI: 10.13040/IJPSR.0975-8232.12(2).776-82

776-782

1413

806

18.

EXERCISE-INDUCED OXIDATIVE STRESS MANAGEMENT BY METHANOLIC EXTRACT OF ZINGIBER OFFICINALIS ON SOME VITAL TISSUES IN MALE RAT

Background: Zingiber officinalis known as ginger, under the family Zingiberaceae, is a popular food spice and occupies an important place in Ayurvedic and traditional medicine. Its rhizome is used as antioxidative, carminative and for chronic diseases. Aims: Study indicated the curative effects of methanolic extract of ginger on severe exercise-induced oxidative damage in vital organs. Materials a...

D. S. Misra, D. Ghosh and R. Maiti *

Department of Physiology, Bankura Christian College, Bankura, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.11(3).1167-75

1167-1175

1412

619

28.

DETERMINATION OF PHYTOCHEMICAL CONTENTS AND ANTIOXIDANT ACTIVITIES OF ETHANOL EXTRACT OF THE LEAVES OF SCURRULA PARASITICA L.

The phytochemical analysis of ethanol extract of Scurrula parasitica showed positive results for alkaloid, saponins, tannin, terpenoids, flavonoids, phenol, reducing sugar and phytosterols whereas glycoside is found to be absent. Total phenol and flavonoid contents were evaluated and found to be total phenolic compounds (101.9-379.1 µg/g tissue) and total flavonoids (72-174.1 µg/g tissue), respe...

J. Laldingngheta * and Lalnundanga and M. Vabeiryureilai

Department of Forestry, Mizoram University, Aizawl, Mizoram, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2211-16

2211-2216

1412

730