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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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5.

REVIEW ON DERIVING A HYPOTHESIS FOR ACHIEVING SUPERIOR BIOAVAILABILITY OF CURCUMIN AS AN ANTITUMOR AGENT

Curcumin, chemically 1,7-bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-diene-3,5-dione derived from Curcuma longa L. is an active chemical constituent used medicinally worldwide from ancient times. Though Curcumin enjoying the reputation of many pharmacological actions, it has certain setbacks with poor bioavailability. The poor water solubility is said to be the reason for poor bioavailability, rathe...

R. Manju and K. Kannan *

Department of Pharmacy, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1381-89

1381-1389

2586

1277

28.

DETERMINATION OF PHYTOCHEMICAL CONTENTS AND ANTIOXIDANT ACTIVITIES OF ETHANOL EXTRACT OF THE LEAVES OF SCURRULA PARASITICA L.

The phytochemical analysis of ethanol extract of Scurrula parasitica showed positive results for alkaloid, saponins, tannin, terpenoids, flavonoids, phenol, reducing sugar and phytosterols whereas glycoside is found to be absent. Total phenol and flavonoid contents were evaluated and found to be total phenolic compounds (101.9-379.1 µg/g tissue) and total flavonoids (72-174.1 µg/g tissue), respe...

J. Laldingngheta * and Lalnundanga and M. Vabeiryureilai

Department of Forestry, Mizoram University, Aizawl, Mizoram, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2211-16

2211-2216

2585

1295

33.

ANTI-AMNESIC ACTIVITY OF ETHANOLIC FLOWER EXTRACT OF IXORA COCCINEA

Usage of medicinal plants for the treatment of various diseases had been started from 1500 BC onwards. Loss of cognition is one of the age-related mental problems and a characteristic symptom of neurodegenerative disorders like Alzheimer’s. Various natural drugs are used for treatment of Alzheimer’s and Parkinsonism, but Available drugs provide symptomatic treatment with known side effects. So...

B. N. B. Vaidehi *, E. Sai Priyanka, J. Ramya, G. Chaitanya Sai and G. Vinaykumar

Aditya College of Pharmacy, East Godavari District, Surampalem, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(12).6464-71

6464-6471

2585

1453

22.

STABILITY STUDY OF NEWLY FORMULATED EMULSION WITH MARKETED FORMULATION

The aim of the article is to formulate and evaluate emulsion also perform comparative study with marketed formulation. Emulsion is a heterogeneous system consisting of at least one immiscible liquid dispersed in another in the form of droplets. Emulsion is prepared with castor oil and liquid paraffin. One marketed formulation was taken for comparison. Identification tests, evaluation tests and sta...

Pratik K. Shinde * and Bharatee P. Chaudhari

YSPM’S, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe, Satara, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1198-02

1198-1202

2585

2475

20.

CITRULLUS COLOCYNTHIS PHYTOSOMES: DEVELOPMENT AND PHYSIOCHEMICAL CHARACTERIZATION

Present work is aimed at development and characterization of phytosomes, novel drug delivery dosage form used to improve the bioavailability of the drug, containing ethanolic, aqueous, dichloromethane and ethyl acetate extract of Citrullus colocynthis to meet the need for better effectiveness and safety. Required phytosomal formulations were developed using different extracts of Citrullus colocynt...

A. Rani *, S. Arora, A. Goyal and A. Sharma

Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.10(10).4568-73

4568-4573

2584

1298

51.

GREEN SYNTHESIS AND CHARACTERIZATION OF COPPER NANOPARTICLES SYNTHESIZED FROM LAWSONIA INERMIS LEAF EXTRACT

Plant diseases caused by microbial pathogen leads to severe economic loss. Attempt to synthesize nanoparticles for this purpose is an economical and effective means to control these pathogens. For this purpose, nanoparticles synthesized via biological means are not only a safer choice but also a big step towards conservation of the integrity of environmental elements. In the present investigation,...

K. Rathore *, D. Hada and K. Sharma

Microbial Research Laboratory, Mohanlal Sukhadia University, Udaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.12(1).477-81

477-481

2584

1498

60.

EVALUATION OF ANTIOXIDANT PARAMETERS OF MUKIA MADERASPATANA

The present study was an attempt to investigate the effect of extracts and fractions of Mukia maderaspatana on glycemia, lipid profile, lipoprotein level and antioxidant profile in STZ induced diabetic rats for 21 days. Diabetes was induced using streptozotocin (50 mg/kg i.p) and after the induction of diabetes the animals were given with MMEE (100 mg/kg, 200 mg/kg), MMCF (100 mg/kg) and MMBF (100...

A. V. S. R. S. Nadh *, P. R. Rao and A. P. Rani

Jawaharlal Nehru Technological University, Kakinada, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(8).3984-88

3984-3988

2583

1243

49.

SOLUBILITY ENHANCEMENT AND DEVELOPMENT OF GUM BASED COLON TARGETED DRUG DELIVERY SYSTEMS OF QUERCETIN

The study aimed to enhance the solubility and develop a polymer (Guar Gum/Xanthan gum) based colon targeted drug delivery system of Quercetin promising in-vitro mouth-to-colon release profile. The solubility of the drug was enhanced by the solid dispersion method using solvent-evaporation technique; the optimized formulation 1:5 (Quercetin: PVP) was targeted to colon. Thermal studies proved that t...

R. R. Kamisetti *, R. R. Katta and M. K. G. Chengespur

Department of Pharmaceutical Regulatory Affairs, Pulla Reddy Institute of Pharmacy, Annaram, Gummadidala, Sangareddy, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.12(2).1123-30

1123-1130

2582

1131

51.

PHARMACOLOGICAL EVALUATION OF ALCOHOLIC EXTRACT OF EUPHORBIA ANTIQUORUM WITH SPECIAL EMPHASIS ON DIABETIC COMPLICATION

Diabetes is a metabolic disorder of carbohydrate, fat and protein metabolism characterized by increased fasting and post prandial blood sugar levels. Diabetes is the most common cause of progressive kidney failure leading to dialysis or transplantation. Nephropathy is reported to develop in 30-40% of patients with diabetes and has become a leading cause of end-stage renal failure worldwide. The va...

P. K. Yadav * and S. S. Sisodia

Bhupal Nobles' College of Pharmacy, Faculty of Pharmacy, Bhupal Nobles’ University, Udaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.11(2).916-21

916-921

2580

1232

9.

OCULAR INSERTS: A PROMINENT TECHNIQUE FOR OCULAR DRUG DELIVERY

The eye is a sensitive organ, and the administration of drugs into the ocular cavity is a tedious task. Ocular insert is the prominent technique to overcome problems associated with conventional dosage forms like repeated administration, drug drainage via lacrimal fluids drainage, formation of crystalline deposits on the cornea, pH instability, pulsed dosing of drugs, etc. This review focuses on d...

A. R. Beldar *, S. S. Kakade and A. V. Bhosale

Department of Pharmaceutics, PDEA`s Shankarrao Ursal College of Pharmaceutical Sciences and Research Centre, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.14(8).3694-03

3694-3703

2580

2007