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EXPLORING ANTIFUNGAL POTENTIAL OF ESSENTIAL COMPOUNDS IN FISH OILS FOR TREATING SKIN INFECTIONS
Skin fungal infections are a significant global public health concern due to growing resistance to traditional antifungal treatments. This study explores the fungicidal properties of key components in fish oils and their potential use in treating cutaneous fungal diseases. Fish oils contain bioactive substances like omega-3 fatty acids (EPA and DHA), vitamins, sterols, and antioxidants, which can ...
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GREEN SYNTHESIS AND CHARACTERIZATION OF COPPER NANOPARTICLES SYNTHESIZED FROM LAWSONIA INERMIS LEAF EXTRACT
Plant diseases caused by microbial pathogen leads to severe economic loss. Attempt to synthesize nanoparticles for this purpose is an economical and effective means to control these pathogens. For this purpose, nanoparticles synthesized via biological means are not only a safer choice but also a big step towards conservation of the integrity of environmental elements. In the present investigation,...
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COVID19: PATHOPHYSIOLOGY, CLINICAL FEATURES, DIAGNOSIS AND MANAGEMENT
SARS-CoV-2 viral cause infection called COVID-19 was initially reported in China has resulted in a pandemic because it has spread in over 210 countries. This review summarized pathophysiology, clinical features, diagnosis, and COVID 19. The spread of SARS-CoV-2 viral infections is a matter of concern because of a mutant variant of virus. The COVID-19 infection is having 14 days incubation period. ...
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EVALUATION OF ANTIOXIDANT PARAMETERS OF MUKIA MADERASPATANA
The present study was an attempt to investigate the effect of extracts and fractions of Mukia maderaspatana on glycemia, lipid profile, lipoprotein level and antioxidant profile in STZ induced diabetic rats for 21 days. Diabetes was induced using streptozotocin (50 mg/kg i.p) and after the induction of diabetes the animals were given with MMEE (100 mg/kg, 200 mg/kg), MMCF (100 mg/kg) and MMBF (100...
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SYNTHESIS, CHARACTERIZATION, BIOLOGICAL AND FLUORESCENT BEHAVIOUR OF METAL (II) COMPLEXES WITH PYRAZOLINE DERIVATIVES
Novel metal complexes of ligands of pyrazoline derivatives were synthesized by the condensation of 1-acetyl-2-hydroxynapthalene and indole-3-carboxaldehyde followed by the condensation of substituted phenylhydrazine. They were characterized by elemental analysis, IR, 1H-NMR, UV-Vis., molar conductance, magnetic susceptibility measurements and electrochemical studies. Based on the magnetic moment a...
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SALUTARY ACTIVITY OF BERBERINE AGAINST DIBUTYLTIN DICHLORIDE INDUCED ACUTE PANCREATITIS IN ALBINO WISTAR RATS
Background: Berberine is a natural alkaloid used as traditional Chinese medicine. Objective: The objective of the present study was to evaluate the effect of berberine on dibutyltin dichloride (DBTC) induced acute pancreatitis in albino Wistar rats. Methods: In this study 24 Wistar rats were randomly selected and divided into four groups. Each group consists of 6 animals. Group-1 (-ve control), Gr...
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ASSOCIATION BETWEEN HYPERURICEMIA, SERUM IRON LEVEL AND POSSIBILITY OF GOUT AMONG SAUDI PATIENTS: A RETROSPECTIVE STUDY
The present study has been undertaken to evaluate the association between serum uric acid levels as a marker of iron overload in Saudi people. A retrospective cohort study was carried out at King Fahad Medical City in the Riyadh-central region of the Kingdom of Saudi Arabia for four months from 1st November 2018 to the end of February 2019 on the random sample of 117 medical files for Saudi patien...
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CITRULLUS COLOCYNTHIS PHYTOSOMES: DEVELOPMENT AND PHYSIOCHEMICAL CHARACTERIZATION
Present work is aimed at development and characterization of phytosomes, novel drug delivery dosage form used to improve the bioavailability of the drug, containing ethanolic, aqueous, dichloromethane and ethyl acetate extract of Citrullus colocynthis to meet the need for better effectiveness and safety. Required phytosomal formulations were developed using different extracts of Citrullus colocynt...
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AN EVALUATION OF THE PROTECTIVE ROLE OF ESCITALOPRAM IN STREPTOZOTOCIN-INDUCED DIABETIC NEUROPATHY
Objective: The aim of the present study was the evaluation of the protective role of escitalopram in streptozotocin-induced diabetic neuropathy. Materials and Methods: Diabetes was induced in Wistar rats with streptozocin 70 mg/kg and animals were divided into four groups namely normal control, diabetic vehicle control, glibenclamide control and escitalopram group. After the 4th week of diabetes...
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EFFECT OF OLANZAPINE ON HYPERTHERMIA IN SEROTONIN SYNDROME MODEL
The serotonin syndrome is a life-threatening adverse drug reaction caused by a significant increase in the concentration of 5-hydroxytryptamine (serotonin) in the central nervous system. The aim of this study was to establish the effects of olanzapine, an antipsychotic drug, on the hyperthermic response in rat experimental serotonin syndrome. In this study, we used an animal model of the serotonin...
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