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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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15.

INHIBITION OF ISLET AMYLOID POLYPEPTIDE FIBRILLATION BY OKRA SEED EXTRACT-COATED GOLD-NANOPARTICLES

In recent work, an ethanolic extract of okra seeds was successfully conjugated onto gold nanoparticles (AuNPs) via a reduction reaction that has been developed by our laboratory. Because of eliciting antioxidant activity and the presence of g-sitosterol in the extract, such synthesis methodology could be applied. The resulting okra-AuNPs were physically characterized by different methods, includin...

S. Manee, M. Wang, F. Usman, P. Wongwitwichot and J. Kaewsrichan *

Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-yai, Songkhla, Thailand.

DOI: 10.13040/IJPSR.0975-8232.11(10).4896-01

4896-4901

2376

1136

47.

COMPARATIVE MODELLING AND DOCKING STUDIES OF CYTOCHROME C OXIDASE SUBUNIT 1 PROTEIN

Cytochrome c oxidase, a mitochondrial metalloenzyme acting as the terminal enzyme of the mitochondrial respiratory chain. It provides a critical function in cellular respiration in both eukaryotes and prokaryotes. The recent development in technology has enabled researchers to understand the genetic, molecular, structural, and functional properties of proteins to identify appropriate targets again...

V. Mallojala, K. Pasam, S. K. Gunda *, S. Bandi and M. Shaik

Bioinformatics Division, PGRRCDE, Osmania University, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.11(10).5148-57

5148-5157

2375

1183

77.

QUALITATIVE, QUANTITATIVE EXPLORATION OF PHYTOCHEMICALS AND DETERMINATION OF ANTIBACTERIAL ACTIVITY OF SARGASSUM WIGHTII

Marine carbohydrates play a crucial role in drug development and disease eradication as it is suggested as a promising bioactive material for its various properties. Seaweeds are the marine macroalgal source that contains a large amount of sulfated polysaccharides. Sargassum wightii (S. wightii) is one of the seaweed which possesses a wide range of pharmacological actions. The aim of the present w...

A. M. Saral * and F. Mathew

Department of Chemistry, School of Advanced Studies Vellore Institute of Technology, Katpadi, Vellore - 632014, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(1).678-83

678-683

2374

1408

61.

EVALUATION OF WOUND HEALING ACTIVITY OF HYDROALCOHOLIC EXTRACT OF FICUS GLOMERATA ON WISTAR ALBINO RATS

Traditionally, Ficus glomerata is used for wound healing activity. Since no detailed scientific data are available regarding the wound-healing activity of F. glomerata, the present study was designed to explore the effect of hydro-alcoholic leaf extract of Ficus glomerata (HEFG) on experimentally induced excision and incision wound models in Wistar rats. The wound-healing efficacy of Hydroalcoho...

K. Roy *, M. Chakraborty and A. Theengh

Department of Pharmacology, Himalayan Pharmacy Institute, Majhitar, Rangpo, East Sikkim, India.

DOI: 10.13040/IJPSR.0975-8232.12(1).554-58

554-558

2374

1204

25.

EVALUATION OF ANTI-ALZHEIMER’S ACTIVITY OF ALCOHOLIC EXTRACT OF CISSUS QUADRANGULARIS STEMS IN WISTAR ALBINO RATS

Alzheimer's disease is the most frequent cause of dementia worldwide and its incidence is increasing due to the world's aging population. Alzheimer's disease (AD) is one of the greatest medical care challenges of our century and is the main cause of dementia and neurodegenerative diseases. Dementia is defined as an acquired loss of cognition in many cognitive domains. Herbal medicine has evolved a...

Shilpa S. Sarvagod * and Vanita G. Kanase

Department of Pharmacology, Oriental College of Pharmacy, Navi Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(4).1657-69

1657-1669

2374

1436

1.

VARIOUS HERBAL PLANTS ARE USED AS ANTICANCER AGENTS

Cancer is the world's second-largest cause of death. Although substantial progress has been made in treating and controlling cancer progression, there are still significant flaws and space for improvement. During chemotherapy, several unfavourable side effects might arise. Natural-derived substances are attracting scientific and academic attention since they are thought to have fewer hazardous sid...

C. Sangavi * and R. Senthamarai

Department of Pharmaceutics, Periyar College of Pharmaceutical Sciences, Tiruchirappalli, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3807-23

3807-3823

2372

1499

4.

ROLE OF NANOMEDICINE TO COMBAT COVID-19- A REVIEW

COVID-19 has been proved to create a pandemic over the world within a few years. All scientists and health workers are trying to develop an effective treatment with collaboration. Various strategies such as antiviral, antibacterial, and antimalarial drugs have been employed to treat COVID- 19, but they were found to relieve the symptoms only. The formation of various variants of the virus in vario...

Sonia, N. Rani, R. Sheoran and N. Pawar

Department of Pharmaceutical Sciences, Chaudhary Bansilal University, Bhiwani, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3560-66

3560-3566

2372

1114

47.

FTMS-ESI CHARACTERISATION OF ETHER EXTRACT OF AZADIRACHTA INDICA LINN. OBTAINED FROM ANANTHAPURAM ANDHRA PRADESH INDIA

Neem (Azadirachta indica) is a member of the Meliaceae family and its role as the health-promoting effect is attributed because it is a rich source of potent biochemicals. It has been widely used in Chinese, Ayurvedic, and Unani medicines worldwide especially in Indian Subcontinent in the treatment and prevention of various diseases. In this present study’s author being investigated and identifi...

V. K. M. Naik *, K. S. Babu, P. M. Reddy and J. Latha

Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(9).4404-08

4404-4408

2370

1261

50.

DESIGN AND OPTIMIZATION OF EXPANDABLE GASTRORETENTIVE PATCH OF METRONIDAZOLE FOR HELICOBACTER PYLORI INFECTION MANAGEMENT

The aim of the present research was to develop and optimize novel expandable gastro retentive formulation of metronidazole to give local action for the management of Helicobacter pylori infection. The formulation contained a drug-loaded sandwich patch prepared by solvent casting method folded into a hard gelatin capsule. Metronidazole being needle shape crystals soluble in 0.1 N HCl, but after dry...

S. Y. Kane * and M. Momin

R. K. University, Rajkot, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.10(11).5216-23

5216-5223

2370

1122

44.

HPTLC FINGER PRINT PROFILE OF ROOT EXTRACTS OF MARTYNIA ANNUA LINN.

The objective of the present study is to evaluate phytochemical composition and HPTLC finger print profile of medicinally useful plant Martynia annua L. (Martyniaceae) root extracts. The CAMAG HPTLC system was used for the finger print profiling of root extract using the mobile phase chloroform: Methanol (9:1 v/v). The profile showed that the root extract of Martynia annua exhibited several peaks ...

R. K. Gupta * and M. Deogade

Department of Dravyaguna, MGACH & RC, Wardha, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.11(7).3450-56

3450-3456

2370

1218