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A SYSTEMATIC REVIEW OF UNANI FORMULATIONS FOR POTENTIAL IN TREATMENT OF HEPATOCELLULAR CARCINOMA
Background: Hepatocellular carcinoma (HCC) represents the third most common cause of death in the world. It is resistant to most chemotherapeutics and associated with a poor prognosis. Unani system of medicine offers effective treatment for various chronic liver diseases. These treatments have shown reversal of inflammation and fibrosis in various clinical conditions. In the present study, we have...
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EFFECT OF HYDROALCOHOLIC EXTRACT OF SIDA SPINOSA L. ON 2,4,6-TRINITRO-BENZENESULFONIC ACID INDUCED ULCERATIVE COLITIS IN RATS
The present study aimed to evaluate the effect of hydroalcoholic extract of Sida spinosa L. (HYSS) in colitis induced in rats by intrarectal administration of TNBS by clinical, morphological and biochemical alterations. The HYSS administered at three different concentrations 100, 200 and 400 mg/kg, p.o. and sulfasalazine (50 mg/kg, p.o) as reference standard for 10 days in colitis induced rats. TN...
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ANALYSIS OF THE EFFECT OF LOW DOSE DOPAMINE IN TREATMENT OF PRERENAL AZOTEMIA IN ADULT PATIENTS ATTENDING NEPHROLOGY UNIT IN NAUTH, NNEWI, NIGERIA
Background: This was a conventional comparative treatment-controlled study designed to analyze the effect of dopamine infusion in the treatment of prerenal azotemia (PRA). Material and Methods: thirty randomized consecutive adult patients (group A= 15, B=15) aged 18 and 58 years with PRA were recruited. Group a received conventional treatment only (fluid replacement and frusemide), while group B r...
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SALVIA HISPANICA (CHIA) SEEDS – A REVIEW ON PHARMACOLOGICAL BENEFITS, NUTRACEUTICAL PROPERTIES, EXTRACTION METHOD AND APPLICATIONS
The plant Salvia hispanica belongs to the family Lamiaceae, a highly valued medicinally important seed, commonly known as chia seeds. About 75% of the fats in chia seeds consist of omega-3 alpha-linolenic acid (ALA), while about 20% consist of omega-6 fatty acid. Omega-3s play an important role in sharpening memory and improving mood. Chia seeds also contain polyunsaturated fatty acids, dietary fi...
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ELECTROCHEMICAL SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF NICKEL OXIDE NANOCLUSTERS
The nanoclusters are having different properties than their bulk material. Hence, the synthesis and applications of nanoclusters of metal oxides have received more attention. Out of many available methods for the synthesis of metal oxide nanoclusters, the electro-chemical reduction method is simple, cheap, and provides pure material hence preferred. The present study describes the synthesis of nic...
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MOSQUITO LARVICIDAL ACTIVITY OF HYPTIS SUAVEOLENS (L) POIT EXTRACTS PURIFIED FRACTION
Bio-pesticides are playing a very important role in controlling mosquitoes and their larvae. In the present scenario, chemical pesticides are causing several side effects on non-target organisms, particularly in men. Moreover, mosquitoes and their larvae become resistant to chemical pesticides; therefore, chemical pesticides are not much more effective. The conventional use of temephos and pyrethr...
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ANTI-DIABETIC EFFECT OF LEAF AND STEM EXTRACT OF MACROTYLOMA UNIFLORUM (LAM.) VERDC IN ALLOXAN INDUCED DIABETIC RATS
Diabetes mellitus (DM) is a metabolic disorder in the endocrine system resulting from a defect in insulin secretion, insulin action or both of them. Adverse side effects of chemical drugs for the treatment of diabetes persuaded the use of medical plants. Macrotyloma uniflorum is a traditionally used plant for the treatment of diabetes is packed with powerful plant constituents with polyphenols, fl...
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TERATOGENICITY AND BACTERICIDAL ACTIVITY OF NANOSYNTHESIZED JUSTICIA ADHATODA IN THE EMBRYOS OF DANIO RERIO
In the present study, Justicia adhatoda was used for synthesizing AgNPs and characterized using UV-visible, FTIR, XRD, and SEM analysis and checked for its teratogenic effect and bactericidal activity. UV–Vis spectra analysis revealed that the synthesized AgNPs had a peak around 434 nm, while XRD and SEM analysis showed that AgNPs have spherical shapes with sizes ranging from 22 to 29 nm. Fourie...
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A COMPARATIVE EVALUATION OF ANTIPLATELET REGIMENS FOR PREVENTION OF RECURRENCE IN PATIENTS WITH ISCHEMIC STROKE – A PILOT STUDY
Background: Prevention of recurrence is important for patients with ischemic stroke. The purpose of the study was to compare the effectiveness of two antiplatelet regimens-aspirin plus clopidogrel versus aspirin plus cilostazol in early secondary stroke prevention using National Institutes of Health Stroke Scale (NIHSS) Scores. Methods: In this study, we randomly assigned 30 patients to receive as...
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EVALUATION OF METHANOLIC EXTRACT OF MACROTYLOMA UNIFLORUM SEEDS ON INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION- IN-VITRO
Seeds of Macrotyloma uniflorum Linn. (Fabaceae) are widely used for treatment in kidney stones in India. In This study evaluates the in-vitro effect of methanolic extract of Macrotyloma uniflorum (MEMU) on calcium oxalate crystallization. A methanolic extract of M. uniflorum seeds at different concentrations (250-1500 μg/ml) was subjected to in-vitro crystallization activity. The obtained results...
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