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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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60.

AN OBSERVATIONAL STUDY REGARDING PRESCRIPTION EVENT MONITORING OF ANTI-HYPERTENSIVE MEDICATIONS AMONGST PATIENTS COMING TO A TERTIARY CARE CENTRE OF NORTHERN INDIA

Hypertension is now defined on the basis of systolic (SBP) and diastolic (DBP) blood pressure levels and classified into stages on the basis of the degree of elevation. The generally recognized cut point for hypertension is an average office BP of 140/90 mmHg or greater, which has been obtained by a recommended standard technique with an accurate manometer and has been confirmed on at least one ot...

S. Mishra *, N. Nigam, S. S. Ahmad, P. Shankar, S. Kumar, V. Kumar and S. Gupta

Department of Pharmacology, Rama Medical College Hospital & Research Centre, Kanpur, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(4).2405-10

2405-2410

2181

1174

19.

EVALUATION OF PHYTOCHEMICAL, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF CURCUMA LEUCORRHIZA (ZINGIBERACEAE) ROXB. RHIZOME

The aim of the present study was to characterize the petroleum ether, chloroform, and ethanol extracts of rhizomes of Curcuma leucorrhiza Roxb and to evaluate their biological activities such as anti-oxidant, anti-bacterial, and anti-fungal activities. Sequential solvent extraction was performed by Soxhlet apparatus using petroleum ether, chloroform, and ethanol, and respective extracts were named...

Rameshor Singh Atom, Warjeet Singh Laitonjam *, Rakhi Khunjamayum, Shaukat Ali M. Shaikh, Raghumani Singh Ningthoujam and Amit Kunwar

Department of Chemistry, Manipur University, Imphal, Manipur, India.

DOI: 10.13040/IJPSR.0975-8232.12(9).4764-73

4764-4773

2181

1069

54.

EFFECT OF PIPER BETLE LEAF EXTRACT AND SYZYGIUM AROMATICUM FLOWER EXTRACT AND THEIR ACTIVE COMPONENT EUGENOL ON THE SURVIVAL OF LUNG ADENOCARCINOMA CELLS (A549)

Medicinal plants are one of the most important resources for developing new lead therapeutic compounds used in various traditional medicines worldwide for thousands of years due to the presence of natural bioactive components, which help in preventing various human diseases. Piper betle Linn belongs to the Piperaceae family, commonly known as Betel and Paan. Betel leaves possess several bioactivit...

C. Azhagumeena, P. R. Padma and S. Sumathi *

Department of Biochemistry, Biotechnology and Bioinformatics, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(4).2349-60

2349-2360

2177

1247

35.

SIMULTANEOUS HPTLC METHOD FOR DETERMINATION OF GALLIC ACID, VANILLIC ACID AND SYRINGIC ACID IN AGRO-INDUSTRIAL WASTE OF DATE FRUITS

Phoenix dactylifera is a medicinally important plant. Fruits are traditionally used for the nutritional purpose. Date seeds are the rich sources of phenolic acids which exhibits strong antioxidant property. HPTLC is a simple, versatile method and it provides visualization of separated constituents. The advantage of this method is this method requires a small amount of sample for analysis. The pres...

K. R. Upadhye and V. N. Jain *

Department of Quality Assurance, Oriental College of Pharmacy, Sanpada, Navi Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(5).2818-22

2818-2822

2177

1077

44.

DEVELOPMENT OF NASAL DRUG DELIVERY SYSTEM OF ATORVASTATIN CALCIUM FOR ENHANCING BIOAVAILABILITY

Atorvastatin calcium is a synthetic lipid-lowering agent used in hyperlipidemia. An oral dose of Atorvastatin calcium ranges from 10mg to 80mg per day. Atorvastatin calcium belongs to BC’s class II drug having low solubility and high permeability. The absolute bioavailability of Atorvastatin calcium is approximately 12%, and the systemic availability of HMG-CoA reductase inhibitory activity is a...

G. Swathi * and G. U. Rani

Department of Pharmaceutics, Sree Dattha Institute of Pharmaceutical Sciences, Ibrahimpatnam, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3887-96

3887-3896

2176

1316

26.

EXTRACTION, CHARACTERIZATION AND INHIBITION OF POLYPHENOL OXIDASE IN SOLANUM MELONGENA

Enzymatic browning is a process that occurs in fruits and vegetables by the enzyme polyphenol oxidase, which results in brown pigments reduce shelf life which indirectly causes huge domestic loss to the farmers during the post-harvesting process. In this context, the present study was carried out to preserve and increase the shelf life of Brinjal vegetables from enzymatic browning using ascorbic a...

S. Vijayanand *, S. Nagasathya and B. Peter

Department of Life Sciences, Kristu Jayanti College (Autonomous), Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(8).4292-01

4292-4301

2176

1477

22.

REINVESTIGATION OF SYNTHESIS OF ENOXAPARIN UNDER PTC CONDITIONS

Heparin is a mixture of glycosaminoglycan (GAG) chains originating from the porcine intestinal mucosa. It is used therapeutically as an anticoagulant for the treatment and prevention of thrombosis. Glyco-saminoglycans such as heparin (H) and heparan sulfate (HS) are considered attractive therapeutic agents because they modulate many biological processes and have been implicated in numerous patholo...

P. Venkatanarayana, B. Prasanna * and N. Seelama

Department of Chemistry, Chaitanya (Deemed to be University), Kishanpura, Hanamkonda, Warangal, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1533-36

1533-1536

2175

1694

45.

FORMULATION AND CHARACTERIZATION OF IBRUTINIB LOADED CYCLODEXTRIN NANOSPONGES

The aim of this study was to explore the feasibility of complexing the poorly water-soluble drug ibrutinib with β-cyclodextrin (β-CD) based nanosponges (NS), which offer advantages of improving dissolution rate and eventually oral bioavailability. Blank NS were fabricated by reacting β-CD with the cross-linker carbonyldiimidazole at different molar ratios (1:2, 1:4 and 1:8). The effect of formu...

G. Surendar * and B. Ramesh

Department of Pharmacy, Career Point University, Kota, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.13(2).930-41

930-941

2174

1216

9.

LOOKING FROM PAST TO PRESENT- CHAKSHUSHYA DRUGS IN BHAVAPRAKSHA NIGHANTU AND RESEARCH DONE ON THEM

Bhavaprakasha is unique in the sense that it shows the slow amalgamation of traditional Indian materiamedica with several new additions which came to the Indian subcontinent through trade and exchanges with foreign civilizations. The Nighantuportion of Bhavaprakasha is an excellent repertoire of herbs and minerals used in Ayurveda. Several plants with properties related to augmentation of ocular f...

A. V. Nair * and K. Sreekumar

Department of Shalakyatantra, Government Ayurveda College, Thiruvananthapuram, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3611-17

3611-3617

2174

1158

23.

ANALYSIS OF KEY SUGAR PHOSPHATE INTERMEDIATES IN GLYCOLYSIS BY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY TO ASSES AND EVALUATE POSSIBLE ALTERATIONS IN METABOLITE POOL OF ERYTHROCYTES IN TYPE 2 DIABETES

In previous studies, it has been shown that the activities of the glycolysis cycle enzyme are significantly altered with changes in kinetic attributes of hexokinase, phosphorfructokinase and lactate dehydrogenase. Moreover, the kinetic parameters of the terminal enzyme lactate dehydrogenase also changed significantly. In view of these observed changes, it was of interest to know if and how the flu...

S. S. Bhise *, J. R. Rao, M. V. Hegde and S. S. Katyare

Poona College of Pharmacy, Department of Pharmaceutical Chemistry, Bharati Vidyapeeth University, Erandawane, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(5).2061-68

2061-2068

2174

975