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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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32.

PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIUROLITHIATIC ACTIVITY OF PUNICA GRANATUM AQUEOUS LEAF EXTRACT

Pashanabheda is used as antiurolithiatic in Ayurveda. In the present study, Punica granatum is used for screening in-vitro antiurolithiatic potentials. Screening of in-vitro antiurolithiatic potentials of aqueous leaf extract of Punica granatum. The extract was subjected to Preliminary phytochemical analysis. In-vitro anti-urolithiatic activity was screened by nucleation and aggregation assay in w...

Keerthana Arra *, P. Rajeshwari and Sive Prasad Panda

Koneru Lakshmaiah Educational Foundation, Vaddeswaram, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(9).4877-82

4877-4882

854

407

28.

ANTIGENOTOXIC EFFECTS OF SILYMARIN AGAINST NICKEL CHLORIDE MEDIATED DNA DAMAGE IN CULTURED HUMAN PERIPHERAL BLOOD LYMPHOCYTES

DNA damage induced by Nickel chloride in lymphocytes has been studied in-vitro. The sister chromatids exchange and single-cell gel electrophoresis (SCGE), or comet assay were used to measure the level of DNA damage in terms of SCE frequency and comet parameters. Silymarin is a natural protective compound, isolated from Silybum marianum seeds and reported for its anti-genotoxic properties. In this ...

Veena Vishwakarma, Sunil Kumar, Bharti Yadav, Ranjan Gupta, Neeraj K. Aggarwal and Anita Yadav *

Department of Biotechnology, Kurukshetra University, Kurukshetra, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.12(10).5431-38

5431-5438

852

313

2.

REVIEW ON ACTIVITY OF CANNABIS TREATMENT ON PARKINSON’S DISEASE

As new treatments and medication are growing rapidly, neurologists are also toward expanding treating patients with idiopathic Parkinson's disease and facing questions regarding cannabis as a treatment elective, particularly for levodopa-safe Parkinson's symptoms. Cannabinoids compounds like delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) are the most abundant chemicals present. Whereas T...

Douglas Zorinmawia Chhakchhuak, G. Swetha Saniya Tabassum and Anjali Raj *

Department of Pharmacology, Pharmacy # 6/9, 1st Cross, Begur Road, Hongasandra, Bengaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.13(6).2221-29

2221-2229

851

427

04.

GENERAL AWARENESS TO COMMON MEDICINAL HERBS, “THE NATURAL, DOESN’T MEANS SAFE” – A REVIEW

The term "Naturals are the safer" is quite trendy, but the incomplete knowledge of the natural herbs interaction may result in several allergies and unwanted effects that may even take life and sometimes be critical to a life-threatening extent. The responsibility of the FDA is to ensure that the safety and efficacy of the drug consumed by humans and veterinary should be worthful and should cause ...

M. S. Prajapati, K. R. Shahir and P. K. Kulkarni *

Pharmaceutical Science, Gahlot Institute of Pharmacy, Koparkhairane, Navi-Mumbai, University of Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(2).520-30

520-530

851

589

20.

ANTIMICROBIAL ACTION OF MANGROVE PLANT EXTRACTS AGAINST SALMONELLA TYPHI AND CANDIDA PARAPSILOSIS CHARACTERISED BY THEIR ANTIOXIDANT POTENTIALS AND BIOACTIVE COMPOUNDS

Plants present in the mangrove ecosystem are underexplored for their natural bioactive agents, including a neglected scope of inventing newer antimicrobials, to combat global crisis mediated by MDR microorganisms. In this study, we investigated four plants-Excoecaria agallocha, Bruguiera gymnorhiza, Avicennia alba and Aegialitis rotundifolia of the Sundarbans, world’s largest mangrove ecosystem ...

Tamanna Sultana, Arup Kumar Mitra and Satadal Das *

Department of Microbiology, St. Xavier’s College (Autonomous), 30, Mother Teresa Sarani, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.12(9).4774-89

4774-4789

851

378

25.

EVOLVING SAFETY CONCERNS ASSOCIATED WITH ANTI-DIABETIC DRUGS

Diabetes Mellitus, a chronic metabolic disorder, is prevalent all over the world nowadays. As a result, it is estimated that it can become an epidemic in some parts of the world soon. The number of affected people could be as double as that of the currently affected patients till the next decade. In order to fulfill the increasing demands of newer, safer, and more effective medications for treatme...

Roma Ghai, Kiran Sharma *, Manisha Prajapati, Ishani Verma, Jaskaran Singh, Harsh Bansal and K. Nagarajan

KIET School of Pharmacy, KIET Group of Institutions, Delhi-NCR, Ghaziabad, affiliated to Dr. A.P.J. Abdul Kalam Technical University, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.13(2).747-54

747-754

850

438

28.

DEVELOPMENT OF VALIDATED HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY DENSITOMETRIC METHOD FOR QUANTIFICATION OF QUERCETIN IN CAPPARIS DECIDUA EDGEW. STEM

Capparis decidua Edgew. (Capparidaceae) is an important medicinal plant widely used in Ayurveda as anti-inflammatory, anti-arthritic, hepatoprotective, diuretic, digestive, laxative, analgesic and anti-asthmatic. In this study, a sensitive and reliable high-performance thin-layer chromatography (HPTLC) method has been developed for the quantification of a flavonol quercetin as an important marker ...

P. D. Verma *, D. M. Gandhi and B. N. Suhagia

Department of Pharmacognosy, L. M. College of Pharmacy, Navrangpura, Ahmedabad, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.12(6).3243-48

3243-3248

850

389

49.

COMPARISON OF ANTIOXIDANT POTENTIAL OF FRESH AND MARKETED SAMPLES OF MEDICINAL PLANT- ECLIPTA ALBA

The present study aimed at comparing the antioxidant potential of three different samples of Eclipta alba-fresh plant, marketed leaf powder (packaged in sealed containers), and marketed whole plant (sold in open bags). The presence of alkaloids, saponins, triterpenes, terpenoids, tannins, steroids, flavonoids, glycosides was confirmed in all three samples. Fresh plant samples showed a higher antio...

S. Sharma, G. Nandi, A. Chourasia, V. Kaushik, J. Bhatia, S. Waikhom, R. Meena and R. Sisodia *

Department of Botany, Maitreyi College, University of Delhi, Chanakyapuri, New Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.12(8).4476-84

4476-4484

850

541

20.

NOVEL FORMULATION AND ANALYTICAL EVALUATION OF BI-LAYERED TABLETS OF ENALAPRIL MALEATE, HYDROCHLOROTHIAZIDE AND NIFEDIPINE

The present research is intended for the formulation development, optimization, and in-vitro evaluation of bi-layer tablets containing Enalapril maleate, hydrochlorothiazide in the immediate release layer and Nifedipine in the sustained release layer based on GEMINEX technology. The impact of formulation variables such as combination of polymers and coating solution on the drug release was evaluat...

Srinivasarao Jagarlamudi * and Gopinath Chakka

Department of Pharmaceutical Science, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.13(8).3174-86

3174-3186

850

427

21.

INFLUENCE OF DIFFERENT SOLVENTS ON ANTIBACTERIAL POTENTIAL OF THREE SPECIES OF HIMALAYAN OAKS

The antibacterial property of three Himalayan Oaks species (Quercus floribunda, Q. leucotrichophora and Q. semecarpifolia) in different solvents against eight gram-positive and gram-negative pathogenic bacteria employing disc diffusion method has been investigated. All the test microorganisms were inhibited significantly by Oaks species at 1000 μg/ml. The MIC and MBC values of each extract (where...

Suresh Chandra Sati, Amrendra Nath Tripathi * and Parikshit Kumar

Department of Botany, D.S.B. Campus, Kumaun University, Nainital, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.13(1).197-05

197-205

849

444