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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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50.

IN-VITRO MUTAGENIC AND CYTOTOXIC ACTIVITY OF NIGELLA SATIVA SEED EXTRACT BY AMES AND MTT ASSAY

In the modern lifestyle, people are prone to disease. The epidemiology study shows that the lung and colon cancer leading position in both the gender around the world at any group. As based on the traditional systems of medicine, the plants can be used for the discovery of new medicine. The aqueous and ethanol extract of Nigella sativa (N. sativa) seeds were evaluated for their genotoxicity using ...

B. Durga *, M. V. D. Prakash and A. Julius

Department of Biochemistry, Prince Shri Venkateshwara Arts and Science College, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5760-65

5760-5765

2179

1285

23.

ANALYSIS OF KEY SUGAR PHOSPHATE INTERMEDIATES IN GLYCOLYSIS BY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY TO ASSES AND EVALUATE POSSIBLE ALTERATIONS IN METABOLITE POOL OF ERYTHROCYTES IN TYPE 2 DIABETES

In previous studies, it has been shown that the activities of the glycolysis cycle enzyme are significantly altered with changes in kinetic attributes of hexokinase, phosphorfructokinase and lactate dehydrogenase. Moreover, the kinetic parameters of the terminal enzyme lactate dehydrogenase also changed significantly. In view of these observed changes, it was of interest to know if and how the flu...

S. S. Bhise *, J. R. Rao, M. V. Hegde and S. S. Katyare

Poona College of Pharmacy, Department of Pharmaceutical Chemistry, Bharati Vidyapeeth University, Erandawane, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(5).2061-68

2061-2068

2179

977

22.

REINVESTIGATION OF SYNTHESIS OF ENOXAPARIN UNDER PTC CONDITIONS

Heparin is a mixture of glycosaminoglycan (GAG) chains originating from the porcine intestinal mucosa. It is used therapeutically as an anticoagulant for the treatment and prevention of thrombosis. Glyco-saminoglycans such as heparin (H) and heparan sulfate (HS) are considered attractive therapeutic agents because they modulate many biological processes and have been implicated in numerous patholo...

P. Venkatanarayana, B. Prasanna * and N. Seelama

Department of Chemistry, Chaitanya (Deemed to be University), Kishanpura, Hanamkonda, Warangal, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1533-36

1533-1536

2178

1697

9.

LOOKING FROM PAST TO PRESENT- CHAKSHUSHYA DRUGS IN BHAVAPRAKSHA NIGHANTU AND RESEARCH DONE ON THEM

Bhavaprakasha is unique in the sense that it shows the slow amalgamation of traditional Indian materiamedica with several new additions which came to the Indian subcontinent through trade and exchanges with foreign civilizations. The Nighantuportion of Bhavaprakasha is an excellent repertoire of herbs and minerals used in Ayurveda. Several plants with properties related to augmentation of ocular f...

A. V. Nair * and K. Sreekumar

Department of Shalakyatantra, Government Ayurveda College, Thiruvananthapuram, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3611-17

3611-3617

2178

1160

46.

EVALUATE THE EFFECT OF BACOPA MONNIERI, EVOLVULUS ALSINOIDES AND TINOSPORA CORDIFOLIA ON BIOCHEMICAL PARAMETERS IN RATS BRAIN

Bacopa monnieri, Tinospora cordifolia, and Evolvulus alsinoides are conventional Ayurvedic floras that are useful in the various neuropharmacological ailment. This research focused on the effect of ethanolic extract of Bacopa monnieri (BME), Tinospora cordifolia (TCE), and Evolvulus alsinoides (EAE) were evaluated alone and in a combination of extracts (CEPs) by using scopolamine-induced oxidative...

A. Gupta *, M. P. Singh and S. S. Sisodia

Department of Pharmacology, Bhupal Nobles’ College of Pharmacy, Bhupal Nobles’ University, Udaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.11(7).3463-68

3463-3468

2177

1761

27.

IN-SILICO ANALYSIS OF POTENTIAL ANTIMYCOBACTERIAL COMPOUNDS PRESENT IN CYNODON DACTYLON

Tuberculosis is one of the major contagious diseases and a leading cause of death in humans. Current treatment methods suffer from a multitude of problems like long duration of treatment, lack of patient compliance, presence of drug-resistant bacteria, etc. To combat the disease effectively, there is an urgent need for the development of new drugs effective against both drug-sensitive and drug-res...

S. B. Alex and M. S. Latha *

Sree Narayana College, Chathannur, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.12(4).2225-31

2225-2231

2177

1084

6.

A COMPREHENSIVE REVIEW OF RECENT AND FUTURE PROSPECTS OF NANOGELS

A hydrogel with strongly cross-linked hydrophilic polymer chains makes up the majority of nanogels, which are essentially nanoparticles. Several hydrophilic functional groups in hydrophilic polymers enable nanogels to absorb large amounts of water. Incredibly stable, adaptable, and responsive to sensory influences, nanogels have the potential to be a safe and effective medication delivery vehicle ...

Vinod Kumar, Prashant Kumar and Saurabh Sharma *

School of Pharmaceutical Sciences, CT University, Ferozepur Road, Sidhwan Khurd, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.13(11).4336-48

4336-4348

2177

4228

5.

CURRENT REGULATORY REQUIREMENTS FOR MEDICAL DEVICES IN US, EU, AND INDIA

Clinical results of various medical treatments using medical devices demonstrate continuous advances, dealing with multiple types of products covering a vast range of applications in the last two decades. Millions of people rely on medical devices to diagnose and manage illnesses. A typical framework for medical device regulations is a whole product life cycle regulatory system that covers product...

N. Suganthi, Kaviya Suresh and B. Anbarasan *

Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, SRIHER (DU), Porur, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.14(10).4733-40

4733-4740

2176

1209

23.

ANTIMYCOBACTERIAL SCREENING OF SELECTED MEDICINAL PLANTS USING MTT AND THE MICROPLATE RESAZURIN ASSAY

Tuberculosis holds one of the top places on the list of the main cause of death in India. At times, the patients fail to respond to treatment with anti-Tb drugs, drug resistance being one of the reasons. The increasing incidence of MDR and XDR-TB highlights the urgent need to search for newer anti-Tb drugs. For last many years, plants have beneficial activity in a different types of diseases produ...

K. D. Jethva *, D. R. Bhatt and M. N. Zaveri

K. B. Institute of Pharmaceutical Education and Research, Gandhinagar, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1537-45

1537-1545

2175

1101

39.

CYTOPROTECTIVE ROLE OF ENCAPSULATED ASTAXANTHIN AGAINST HEPATO-CELLULAR CARCINOMA (HepG2) CELL LINE

Astaxanthin (3,3′-dihydroxy-β, β′-carotene-4,4′-dione) is a xanthophyll carotenoid, which is found in Haematococcus pluvialis, Chlorella zofingiensis, Chlorococcum, and Phaffiarhodozyma. Astaxanthin play major role as a nutritional supplement, antioxidant and anticancer agent, anti-diabetes, cardiovascular diseases, and neurodegenerative disorders. In our previous study, astaxanthin was fi...

V. Suganya and V. Anuradha *

PG and Research Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(1).372-84

372-384

2174

1309