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EVALUATION OF CYANIDIN-3-O-GLUCOSIDE FROM DIFFERENT BLACK RICE VARIETIES OF MANIPUR UTILIZING FTIR SPECTROSCOPY AND HPTLC METHOD
Black rice is a rice species, Oryza sativa Linne (Gramineae), which is sticky, high in nutrients, and primarily grown in Asia. In recent years, the health benefits of black rice varieties have been reported due to the presence of a bioactive compound, anthocyanin, which has highly potent activity with high macronutrients. The present study aimed to evaluate and quantify the metabolites, focusing o...
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ANTIHYPERGLYCEMIC POTENTIAL OF TEAK SEEDS IN ALLOXAN INDUCED DIABETIC RATS
Tectona grandis is famous as a valuable timber hold an extensive range of applications around the sphere. In addition to its enormous uses in the timber industry, all the parts are cherishing with extensive use in traditional medicine and possess significant pharmacological properties. In search of drugs for diabetes, the methanolic seed extract which is prepared by the Soxhlet apparatus, was used...
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LOOKING FROM PAST TO PRESENT- CHAKSHUSHYA DRUGS IN BHAVAPRAKSHA NIGHANTU AND RESEARCH DONE ON THEM
Bhavaprakasha is unique in the sense that it shows the slow amalgamation of traditional Indian materiamedica with several new additions which came to the Indian subcontinent through trade and exchanges with foreign civilizations. The Nighantuportion of Bhavaprakasha is an excellent repertoire of herbs and minerals used in Ayurveda. Several plants with properties related to augmentation of ocular f...
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DEVELOPMENT OF NASAL DRUG DELIVERY SYSTEM OF ATORVASTATIN CALCIUM FOR ENHANCING BIOAVAILABILITY
Atorvastatin calcium is a synthetic lipid-lowering agent used in hyperlipidemia. An oral dose of Atorvastatin calcium ranges from 10mg to 80mg per day. Atorvastatin calcium belongs to BC’s class II drug having low solubility and high permeability. The absolute bioavailability of Atorvastatin calcium is approximately 12%, and the systemic availability of HMG-CoA reductase inhibitory activity is a...
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SCHIFF BASE: A REVIEW OF PHARMACOLOGICAL ACTIVITIES
Schiff bases are generally aldehyde or ketone-like compounds in which an imine or azomethine group replaces the carbonyl group. They are versatile and exhibit a broad range of pharmacological activities as antimicrobial, antibacterial, antifungal, antiviral, and anticonvulsant. Anti-cancer activity has been used widely for industrial purposes or therapeutic use. Thus, Schiff bases are highly desir...
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DEVELOPMENT AND EVALUATION OF HYDROCORTISONE-LOADED NIOSOMAL GEL
Objective: The present research work was to formulate optimize and evaluate hydrocortisone-loaded niosomal gel for the management of rheumatoid arthritis. Method: Niosomal gel was successfully prepared by lipid-thin film hydration process and optimized by using 23 full factorial designs using three independent variables (tween 80 concentration, cholesterol concentration, and sonication time) and t...
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INDIGENOUS AND UNDER-UTILISED OIL SEEDS OF BOTSWANA: PROXIMATE COMPOSITION, PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY
Proximate composition, qualitative screening for phytochemicals (terpenoids, steroids, tannins, oxalates, coumarins, phenols, saponins, and flavonoids) and antioxidant properties in four selected indigenous oilseeds: morama (Tylosema esculentum), mongongo (Schinziophyton rautenenii), mogose (Bauhinia petersiana) and kgengwe (Citrulus lanatus (Thunb.) Mansf.) from Botswana was examined. A significa...
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CURRENT REGULATORY REQUIREMENTS FOR MEDICAL DEVICES IN US, EU, AND INDIA
Clinical results of various medical treatments using medical devices demonstrate continuous advances, dealing with multiple types of products covering a vast range of applications in the last two decades. Millions of people rely on medical devices to diagnose and manage illnesses. A typical framework for medical device regulations is a whole product life cycle regulatory system that covers product...
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NUTRIMILLET INSIGHTS: A REVIEW OF MILLET VARIETIES AND ADVANCED PROCESSING TECHNIQUES FOR ENHANCED NUTRITIONAL IMPACT
Millets are a group of small-seeded, grains that have gained renewed attention in recent years due to their high nutritional value and sustainable agricultural practices. This abstract provides an overview of millets, their processing methods, and their remarkable nutritional benefits, highlighting their potential to address global food and nutrition challenges. Millets have been cultivated for th...
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FORMULATION AND DEVELOPMENT OF HYDROGEL CONTAINING TRIAMCINOLONE ACETONIDE LOADED NANOSPONGES
The ideal of the exploration is to formulate hydrogel containing nanosponges of Triamcinolone acetonide for the treatment of Psoriasis. Psoriasis is presently treated with a numerous of topical and systemic remedies. Numerous of these treatments, still, are costly and involve adverse effects, similar as immunosuppression. As a result, there is a need to develop curatives that are effective, have l...
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