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EVALUATION OF PHARMACOGNOSTICAL AND PHYSICOCHEMICAL PARAMETERS OF STEM OF ACACIA ARABICA WILLD.
Acacia Arabica Willd.(syn: Acacia nilotica) is a thorny tree belonging to the family Fabaceae and subfamily Mimosoideae. Gum acacia, an exudation obtained from this plant, is included in the GRAS category and used widely as pharmaceutical aid. The plant contains flavonoids, tannins, and phenolic compounds as its phytoconstituents. The plant possesses antioxidant, antipyretic, antimicrobial, antivi...
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EVALUATING PHARMACOGNOSTIC PARAMETERS AND MUTAGENIC ACTIVITY OF KHAYA SENEGALENSIS (DESR.) A. JUSS.
The stem bark of Khaya senegalensis, known as mahogany is commonly sold on the Ghanaian market for the treatment of numerous ailments. To ensure its safe and efficacious use, there is a need to ensure that this plant material is of the best quality. Quality will involve ensuring its identity, purity and content are up to recommended standards by applying available and relevant methods. As a means ...
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OPTIMIZATION OF ANALYTICAL METHOD FOR QUANTIFICATION OF 5-METHOXYCANTHIN-6-ONE BY FACTORIAL DESIGN AND PRELIMINARY STABILITY TEST
Studies of natural products emerge as an important medicinal resource. An example is the use of Zanthoxylum chiloperone (Rutaceae) for medicinal purposes against neglected diseases, as for example, Chagas disease and leishmaniasis. The analysis of the chemical composition of this medicinal plant was carried out by chromatrographic techniques to evaluate its pharmacological applications. The use of...
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DEVELOPMENT OF ANALYTICAL METHOD AND VALIDATION OF NADOLOLIN PURE AND PHARMACEUTICAL FORMULATIONS USING UV-SPECTROPHOTOMETRY AND SPECTROFLUORIMETRY
The development of analytical methods is in need for the estimation of drugs in pure and different pharmaceutical formulations. A simple, sensitive, rapid, accurate, precise and economic spectrophotometric and spectro-fluorimetric method was developed and validated for Nadolol in pure and pharmaceutical formulations. The proposed method was validated according to the International Conference on Ha...
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A REVIEW ON MECHANISTIC ASSESSMENT OF HEPATOTOXICITY AND MEDICINAL PLANTS WITH HEPATOPROTECTIVE POTENTIAL
The liver is the most important organ in the body that plays a central role in the detoxification and excretion of many exogenous and endogenous compounds. Due to these functions, hepatic diseases continue to be among the main threats to public health, and that challenges health care professionals. Many liver diseases are chronic, meaning they last for years and may never go away. But even chronic...
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IN-VITRO AND IN-VIVO QUANTITATIVE ESTIMATION OF TOTAL PHENOLS, ASCORBIC ACID CONTENT AND ANTIOXIDANT ACTIVITY IN NORMAL FLOWER AND FLOWER GALL OF CRATAEVA RELIGIOSA
Plant galls are remarkable close associations between plants and insects, in which the plant produces an abnormal growth of tissue in response to a specific stimulus from the attacking insect. The present investigation was undertaken to assess the antioxidant activity as well as the total phenols and ascorbic acid content in in-vivo (normal flower and galled flower) and in-vitro (unorganized stati...
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ANTI-INFLAMMATORY ACTIVITY POTENTIAL OF ARECA CATECHU LEAF EXTRACTS-AN IN-VITRO STUDY
Areca catechu L. (Arecaceae) is a species of palm mainly grown in Asian countries for seed crop. Areca nut leaves are commonly used in traditional systems of medicine against various ailments. There is a need for identifying native natural plant sources to acquire their recognized medicinal properties, which may widen them to use as new therapeutics for various diseases. Phytochemical investigatio...
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EFFICACY OF PSORINUM IN CHRONIC URTICARIA: A CASE REPORT
Chronic urticaria is a popular skin complaint that is characterized by wheals of various sizes surrounded by erythema and associated with itching and burning as a consequence of Type1 hypersensitivity reaction mediated by IgE antibodies to specific allergen. Most of the population (>20%) have urticaria once somewhere in the life. The conventional management of this condition is associated with ...
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HEPATOPROTECTIVE FUNCTION AS WELL AS SOLUBILITY AND ORAL BIOAVAILABILITY OF NANO-BASED SILYMARIN: A POTENTIAL REVIEW
Silymarin is a mixture of flavonolignan and polyphenolic bioactive natural products found in the milk thistle plant Silybum marianum. It has anti-oxidant, anti-inflammatory, anti-cancer, and antiviral activities potentially useful in treating several liver disorders, such as chronic liver diseases, cirrhosis and hepatocellular carcinoma. However, the benefits are curtailed by its extremely poor wa...
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THE INFLUENCE OF DIETARY COMPOSITION TO METABOLIC SYNDROME INCIDENCE
Metabolic syndrome is a group of several clinical conditions which is related to the prevalence of another disease such as cardiovascular disease, diabetes mellitus (DM) or increased fasting blood glucose level, visceral obesity, hypertension, etc. The major factor that affects the metabolic syndrome occurrence is diet composition.This research aimed to determine the influence of diet composition ...
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