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TECOMELLA UNDULATA (SM.) SEEM.- GC-MS ANALYSIS OF FLAVONOIDS AND INHIBITORY ACTIVITY AGAINST PATHOGENIC MICROBES
Tecomella undulata (Sm.) seem is a monotypic genus belonging to family Bignoniaceae. The plant holds the tremendous potential of medicinal value and has been traditionally used in various ailments like syphilis, leukoderma, blood disorders, to name a few. The plant has gained prominence due to the presence of some prominent secondary metabolites. The present study focuses on the GC-MS analysis of ...
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BIOSYNTHESIS AND CHARACTERIZATION OF GOLD NANOPARTICLES FROM CEIBA PENTANDRA (L.) GAERTN BARK AND EVALUATION OF ITS ANTIBACTERIAL AND ANTICANCER ACTIVITY
The present investigation was aimed at synthesis, characterization and in-vitro antibacterial and anticancer activities of synthesized gold nanoparticles using bark extract of Ceiba pentandra (L.) Gaertn. The synthesized AuNPs were confirmed by a UV-vis spectrometer through observing the surface plasmon resonance peak at 535 nm. Various other techniques, such as Fourier transform infrared spectros...
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BIOLOGICAL SCREENING AND PHYTOCHEMICAL INVESTIGATION OF MERREMIA EMARGINATA LEAVES
The dried leaves of Merremia emarginata Burm. F were screened for antitubercular, cytotoxic, and anti-inflammatory activities. The antimycobacterial activity of compounds was assessed against Myco-bacterium tuberculosis using microplate Alamar Blue assay (MABA), and the cytotoxic activity was studied on Hela (Human cervical carcinoma), MCF-7 (Human breast carcinoma) cell lines. A prenylflavonoid, ...
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A MINI REVIEW ON ADVANCES IN TRANSDERMAL DRUG DELIVERY SYSTEM
Currently, oral drug delivery and parenteral drug delivery are used for the treatment of various diseases. In the oral drug delivery system, due to the first-pass metabolism and acidic environment of the gastrointestinal route, the drug exposes to acids and enzymes present in the gastrointestinal tract, which may lead to degradation of the compound, which ultimately results in poor bioavailability...
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A REVIEW ON WOUND AND ADVANCEMENT IN HEALING STRATEGIES
Wound healing is a complex and dynamic physiological process that occurs by a sequence of interrelated molecular events that should work together in a proper manner and time to restore cellular function and tissue integrity. These physiological phases occur efficiently in normal healthy volunteers and/or under normal conditions. But, in some cases, these events are retarded, which results in hard-...
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EFFECT OF VERMIWASH AND PLANT GROWTH REGULATORS ON GROWTH AND STEM ANATOMY OF HIBISCUS CANNABINUS L.
Growth and development events in plants are controlled by growth regulators and Phytohormones. These are found naturally in plants. Environmental Pollution is one of the major problems and reactions caused by artificial growth regulators and their low biodegradability has urged us to search for new biofertilizers with growth-regulating activity. Vermiwash is a liquid fertilizer that has been shown...
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ASSESSMENT OF PRETERM NEONATES’ RESPONSE TO TACTILE AND KINESTHETIC STIMULATION
Objective: To assess the response of Preterm neonates to Tactile and Kinesthetic Stimulation. Methods: The study was conducted in a Neonatal Intensive Care Unit of a tertiary care hospital in India. Twelve stable preterm neonates were selected as per the inclusion and exclusion criteria and randomized into the intervention and control group. Seven days of tactile and kinesthetic stimulation was gi...
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ANTIHYPERGLYCEMIC POTENTIAL OF TEAK SEEDS IN ALLOXAN INDUCED DIABETIC RATS
Tectona grandis is famous as a valuable timber hold an extensive range of applications around the sphere. In addition to its enormous uses in the timber industry, all the parts are cherishing with extensive use in traditional medicine and possess significant pharmacological properties. In search of drugs for diabetes, the methanolic seed extract which is prepared by the Soxhlet apparatus, was used...
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IDENTIFICATION OF BIOACTIVE COMPOUNDS FROM RHIZOPHORA MUCRONATA METHANOLIC LEAF EXTRACT BY GC-MS ANALYSIS
Herbal medicines play an important role in cancer prevention. Mangroves have been used worldwide due to the presence of various bioactive metabolites in it. The specific medicinal properties of Rhizophora mucronata have been an interest in preventing breast cancer. Mangroves Rhizophora mucronata belongs to family Rhizophoraceae. The leaf extract reveals various roles in folk remedies to treat vari...
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PHARMACOKINETIC EVALUATION OF GENTISIC ACID IN RATS: ORAL VERSUS INTRAVENOUS ADMINISTRATION
Gentisic acid (2, 5-dihydroxybenzoic acid) is a diphenolic compound, present abundantly in natural sources. It possesses several pharmacological activities such as nephroprotective, hepatoprotective, neuroprotective, etc. However, the available literature on oral absorption of gentisic acid is scarce. Thus, the aim of the present study was to determine the pharmacokinetic parameters and bioavailab...
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