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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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56.

METHODS OF EXTRACTION AND FRACTIONATION OF BIO-ACTIVE COMPONENTS OF MORINDA COREIA FOR ANTI-TUBERCULAR AND ANTICANCER ACTIVITIES

In Asian countries, roots, barks, stems, leaves, and fruits of plants belonging to the Morinda species are considered as valuable traditional herbs. They are used in folk medicine for the treatment of many diseases, including diabetes, high blood pressure, and cancer. Anti-tubercular and cytotoxic activities of Morinda citrifolia (noni) have been reported, but Morinda coreia has not been explored ...

A. S. Avasthi, M. Bhatnagar, A. Thirumoorthy, W. Selvamurthy, N. Sinha and S. Ghosal *

Center for Plant and Environmental Biotechnology, Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(8).4062-69

4062-4069

2498

1197

33.

ACCELERATED STABILITY STUDY OF ARSENAZO III USED FOR DETECTION OF CALCIUM FROM BIOLOGICAL SYSTEM THROUGH UV-SPECTROPHOTOMETER, BIOCHEMISTRY ANALYZER, PH METER, HPLC AND HPTLC

Objective: Stability of In-vitro Diagnostics (IVDs) reagents was performed to check its quality standards, performance, and linearity. IVDs like Calcium reagent containing Arsenazo III were studied by Accelerated stability studies by considering temperature, pH, and light parameters. Materials and Methods: Stability data were obtained by using different instruments like UV spectrophotometer, Bioch...

J. R. Kamble, A. S. Sherikar ⃰ and J. I. Disouza

Department of Quality Assurance, Tatyasaheb Kore College of Pharmacy, Warananagar, Panhala, Kolhapur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1615-23

1615-1623

2498

1333

57.

ASSESSMENT OF MICROBIOLOGICAL QUALITY AND ORGANOLEPTIC CHANGE ON STORAGE DURATION OF STANDARDIZED COOKIES PREPARED BY BLEND OF LOTUS STEM POWDER WITH REFINED WHEAT FLOUR FOR DETERMINATION OF ITS SHELF LIFE

Incorporating the under-consumed super food ingredients rich in nutrients or functional compounds is a growing concern in healthcare product formulation. Health-ensuring cookies blend with Nelumbonucifera (Lotus) stem powder were standardized in the laboratory and found its acceptable form with comparatively higher acceptability and good flavour profile. Safety assurance is also a part of product ...

Aamena Zaidi *, Arvind K. Srivastava, Kahkashan Parveen and Praveen Katiyar

Department of Food and Nutrition, Era University, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.14(5).2613-18

2613-2618

2498

1203

18.

MOLECULAR DOCKING ANALYSIS OF PLANT PHYTOCOMPOUNDS AS PROMISING INHIBITORS AGAINST LASB VIRULENCE PROTEIN – AN IN-SILICO AND IN-VITRO APPROACH

Pseudomonas aeruginosa is a Gram-negative pathogenic bacterium that can cause a variety of hospital-acquired diseases. It is a multidrug-resistant bacterium and can survive a wide range of antibiotics; hence there is a concern about its limited therapy options. In this scenario, the discovery and development of novel antibiotics are in high demand. In our research work, molecular docking a Bioinfo...

S. L. Vidya and R. Sathishkumar *

Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.14(9).4419-31

4419-4431

2497

1166

49.

ANGIOTENSIN CONVERTING ENZYME INHIBITION: A MODIFYING PLAYER ON ATHEROGENESIS IN HEMODIALYSIS PATIENTS WITH HEPATITIS C INFECTION

Background and Aim: This study aimed to investigate certain non-traditional risk factors for atherosclerosis in CKD hemodialysis patients with and without HCV infection. Methods: The eligible hemodialysis patients attending our renal dialysis unit were subjected to demographic assessment, testing for HCV infection, basic biochemical profile, and assaying for serum insulin levels, angiotensin conve...

R. H. M. El-deen *, M. M. A. Khalifa, A. M. Taye and M. M. Khattab

Department of Pharmacology & Toxicology, Faculty of Pharmacy, Deraya University, Minia, Egypt.

DOI: 10.13040/IJPSR.0975-8232.10(12).5622-31

5622-5631

2497

1142

58.

PHARMACOGNOSTIC STUDIES AND MONOGRAPHIC DEVELOPMENT OF FICUS GLOMERATA ROXB. FROM THE GREAT GANGETIC PLAIN

In this study attempt has been made to develop the monographic parameters for Ficus glomerata Rox. leaves were collected from Gangetic plains (Lucknow). Under the study, pharmacognostic parameters were performed including macroscopic characters, microscopic characters, physicochemical parameters (extractive values, ash values, pH analysis, LOD), and preliminary phytochemical screening. Apart from ...

P. Deep *, A. Mishra and N. Verma

Amity Institute of Pharmacy, Amity University, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(2).971-77

971-977

2497

1235

51.

PROTECTIVE EFFECT OF NIGELLA SATIVA L. SEEDS EXTRACT ON REPRODUCTIVE TOXICITY INDUCED BY FLUORIDE, ALUMINIUM AND THEIR COMBINATION IN SWISS ALBINO MALE MICE

The aim of the present study was to investigate the possible role of Nigella sativa L. seeds extract on fluoride, aluminum and their combination induced reproductive toxicity in Swiss albino male mice. Nigella sativa L. known as black seeds is used as a form of traditional medicinal plant. Fluoride and aluminum are omnipresent metals and are tremendously used in industries, pharmaceuticals, and fo...

T. Patel and L. Shahani *

Department of Zoology, IIS (Deemed to be University), Jaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.11(12).6358-70

6358-6370

2497

1086

29.

A STUDY OF ANALYTICAL METHOD DEVELOPMENT, VALIDATION AND FORCED DEGRADATION FOR SIMULTANEOUS ESTIMATION OF GLYCOPYRROLATE AND FORMOTEROL FUMARATE IN BULK DRUG BY UHPLC METHOD

The present study was proposed to develop a simple, rapid, and economical UHPLC method was described for the method development, validation and forced degradation for the simultaneous estimation of glycopyrrolate and formoterol fumarate in bulk drug. The chromatographic conditions were observed in the column using Zorbax RXC18 (150 × 4.6 mm) 5 µm using a mobile phase composition of Water: Aceton...

R. K. Banoth * and R. L. Nethikoppula

Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam (Women’s University) Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3781-90

3781-3790

2497

1836

18.

FLASH RELEASE ORAL FILM OF CANDESARTAN CILEXETIL FORMULATION AND IN-VITRO EVALUATION

In the present study, to develop a novel flash release fast dissolving oral film of candesartan cilexetil to achieve rapid dissolution and further improve the bioavailability of the drug. Also, to resolve the swallowing problems in pediatrics, geriatric patients by rapid dissolution in saliva and improve the patient compliance. Fast dissolving flash release oral flim of candesartan cilexetil was f...

Chandrasekar G, Abdual Hasan Sathali A *, Umamaheswari D and Prabhu R

Department of Pharmaceutics, College of Pharmacy (COP), Madurai Medical College, Madurai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(9).4753-63

4753-4763

2492

1169

3.

A COMPREHENSIVE REVIEW ON REGULATION CONCERNS FOR IMPORT AND EXPORT OF PHARMACEUTICAL DRUGS AND GENETIC PRODUCTS IN INDIA, BRITAIN AND SWITZERLAND

Biopharmaceutical technologies used to create biodegradable materials from biological agents fall within a broad spectrum. The production of bioproducts has grown cleaner and more dependable with the adoption of novel biotechnological approaches. The original study objective was to investigate the legal difficulties surrounding the purchase and sale of biological as well as pharmaceutical products...

S. Princely Ebenezer Gnanakani *, L. N. Srilekha, K. P. S. Praneetha and G. Sumalatha

Department of Pharmaceutical Biotechnology, Vikas Institute of Pharmaceutical Sciences, Rajahmundry, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(1).20-34

20-34

2491

1291