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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Most Cited

CITATIONS REPORT: (Source- Google Scholar)
 
Year 202020212022Total
No. of Published Articles 745760548 2053
Citations 69926321 983
Projected Impact Factor 5.22.730.64  
Total Citations: 58203
 
Title
Views
PDF
Cited
20.

ANTIDIARRHOEAL ACTIVITY OF LEAF EXTRACT OF ANOGEISSUS LATIFOLIA WALL IN EXPERIMENTALLY INDUCED DIARRHOEA IN RATS

Aim: To evaluate the antidiarrhoeal activity of methanolic leaf extract of Anogeissus latifolia. Material and Methods: The methanolic extract was evaluated using rodent animal models like castor-oil induced diarrhoea and castor-oil induced enteropooling. The phytochemical constituents were also planned to screen by using standardized methods. The plant is traditionally used for the treatment of...

G. Shashi Priya*, K. Hemamalini and M. Vijusha

Department of Pharmacology, Teegala Ram Reddy College of Pharmacy, Meerpet, Hyderabad, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1776-79

1776-1779

4147

1115

22.

A PHARMACOPHORE BASED DRUG DESIGN APPROACH TO OVERCOME IMATINIB RESISTANCE AND GET MORE POTENT BCR-ABL TYROSINE KINASE INHIBITOR

BCR-ABL Tyrosine Kinase inhibitor is an ideal pharmacological target for Chronic Myeloid Leukemia (CML). After the effective use of Imatinib as a therapeutic agent for Chronic Myeloid Leukemia, resistance has been observed in much patience with the treatment of Imatinib. The main objective of this study is to develop some new novel BCR-ABL Tyrosine Kinase inhibitor for the treatment of Chronic Mye...

Abhishek Thakur

Department of Pharmaceutical Sciences; Birla Institute of Technology, Mesra, Ranchi -835215, Jharkhand, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1788-00

1788-1800

4818

1460

41.

EVALUATION OF ACUTE TOXICITY STUDY AND HAIR GROWTH PROMOTING ACTIVITY OF TRICHUP TABLET

Hair loss problems can affect physical and mental health of human and have particular relevance during the aging process. In an effort to find solution of such problems, an attempt has been made to evaluate the hair growth promotion activity of a herbo-mineral Ayurvedic formulation, Trichup Tablet. Safety of drug was also evaluated by conducting acute toxicity study as per OECD guideline. For eval...

Hardik Soni*, Ekta Rabadiya , Maitreyi Zaveri , Sonal Patel , Ghanashyam Patel

Vasu Research Centre A division of Vasu Healthcare Pvt. Ltd. 896/A, GIDC, Makarpura, Vadodara – 390010, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1931-36

1931-1936

4351

1887

47.

ANTI- CONVULSANT PROFILE OF AQUEOUS EXTRACT OF SAPINDUS LAURIFOLIA IN EXPERIMENTAL ANIMALS

Objective: The aim of the present study was to evaluatethe anti convulsant property of aqueous extract of Sapindus laurifolia in Pentylenetetrazole (PTZ) and MES induced convulsions in experimental models. Materials & Methods: The purpose of this study is to explore the anticonvulsant activity of ethanolic extract of Momordica tuberosa using Pentylenetetrazole and maximal electric shock induce...

N. Siva Kumar *, N. Raveendra Kumar and Parabattula B. Gangadhar

Associate Professor, Alluri Sitaramaraju Academy of Medical Sciences (ASRAM), Eluru, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).1968-72

1968-1972

3519

1461

56.

EVALUATION OF ANALGESIC ACTIVITY OF SOME NOVEL SUBSTITUTED L-ARGININE ANALOGUES

A series of novel L-arginine analogues were synthesized characterized and screened for analgesic activity by acetic acid induced analgesia model. The purity of the synthesized compounds has been characterized by various analytical techniques such as UV, FTIR and TLC. The synthesized compounds were evaluated for analgesic activity by acetic acid induced analgesia in mice using paracetamol as the st...

S. K. Arifa Begum, M. Madhuri, A.Rajani and K. Hemamalini*

Associate Professor & HOD, Department of pharmacology, Teegala Ram Reddy College of Pharmacy, Meerpet, Hyderabad, AP, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(5).2038-40

2038-2040

3067

1291

13.

NIGELLA SATIVA AMELIORATES OXIDATIVE STRESS INDUCED BY DIETHYL PHTHALATE – AN IN VITRO STUDY

The present experiment was designed to assess oxidative stress, if any, caused by diethyl phthalate and its amelioration by Nigella sativa seed extract. For this, the liver and kidney homogenates were treated with different concentrations (10-40 µg/mL) of DEP with or without Nigella sativa seed extract. Lipid peroxidation, a marker for oxidative stress along with total protein content was analyze...

Heena Prajapati and Ramtej J. Verma*

Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad- 380 009, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2203-09

2203-2209

3238

1311

23.

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF 3-(1H-BENZO[d]IMIDAZOL-2-YLSULFANYL) METHYL-4-[PHENOXY(PHENYL) ACETAMIDO)-5-MERCAPTO-1,2,4-TRIAZOLE AND RELATED ARYLOXY COMPOUNDS

A series of new 1H-benzo[d]imidazole derivatives of 3, 4-substituted triazole. 3-(1H-Benzo[d]imidazol-2-ylsulfanyl) methyl-4-[phenyloxy(phenylacetamido)]-5-mercapto-1,2,4-triazole and related aryloxy compounds were synthesised, analysed and characterised by FTIR, 1HNMR and elemental analysis. These compounds were screened for antibacterial and antifungal activity. The antibacterial activities were...

Debojyoti Chakraborty* and S.R. Sharma

NIT, Patna, Bihar, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2276-84

2276-2284

3225

1323

55.

DEVELOPMENT AND CHARACTERIZATION OF BILAYERD TRANSDERMAL FILM OF DICLOFENAC DIETHYLAMINE

The aim of this research work was to develop and characterise bilayer film and to investigate its potential as slow-release wound healing vehicle. The bilayer is composed of an upper layer impregnated with Diclofenac diethyl amine and a drug-free lower layer, which acted as a rate-controlling membrane. Solvent casting technique was employed to prepare transdermal films. Pre formulation studies are...

Potlapally Laxmi*, Azeez Mohammad and G. Shirisha

Department of Pharmaceutics, Venkateshwara Institute of Pharmaceutical Sciences, Cherlapally, Nalgonda-508001, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2508-14

2518-2524

3660

1521

57.

EXPRESSION OF CHICKEN ANEMIA VIRUS VP3 GENE IN HeLa CELLs

Chicken anemia virus (CAV) encodes the protein VP3 also named “apoptin” that specifically induces apoptosis in human tumor cells. In this study, the VP3 gene cloned in p VAX1 plasmid vector was transfected in HeLa cells. The expression of CAV VP3 gene was detected using immunoperoxidase test and indirect fluorescent antibody technique. High level of gene expression was observed in HeLa cell cu...

Raushi Maurya* and Anant Rai

Mewar University, Chittorgarh, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2525-28

2535-2538

3430

1283

60.

ISOLATION OF NATURAL BINDING AGENT FROM EULOPHIA OCHREATA LINDL. AND ITS EVALUATION

Aim and objective: To isolate the natural herbal binding agent from Eulophia ochreata Lindl. and study its evaluation properties using diclofenac as a model drug. Principle: Binders confer structural strength required by tablets during processing, handling, packaging and transportation. A number of plant mucilage, gums/hydrocolloids have been used as binding agents, suspending or emulsifying ag...

A.A. Koparde* and C.S. Magdum

Assistant Professor, “Prabhananda”, Rukmininagar, Part-I,B-8, Karad 415110, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2546-51

2556-2561

3870

1223