Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
BIOELECTRONIC MEDICINES: INNOVATION IN DISEASE TREATMENT
Innovation in technology is required to change the world. Bioelectronic medicine is the consolidation of molecular medicine, neuroscience, engineering, and computing to develop a device to diagnose and treat diseases. The mechanisms of Bioelectronic medicine for neural control of a biological process that underlie disease and the development of devices to modulate these speciļ¬c neural circuits a...
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MOLECULAR VERSUS CONVENTIONAL TECHNIQUES FOR THE DETECTION OF STAPHYLOCOCCUS AUREUS, PSEUDOMONAS AERUGINOSA AND CANDIDA ALBICANS IN NON-STERILE PHARMACEUTICAL PREPARATIONS
Notable progress has been made in methods that encourage the use of PCR as a rapid and accurate tool in quality evaluation of pharmaceuticals. In this study, monoplex and multiplex PCR based assays were developed and compared with standard conventional methods for rapid detection of three specified topical indicator pathogens, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans, in...
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PHYTOCHEMICAL SCREENING AND EVALUATION OF ANALGESIC AND THROMBOLYTIC ACTIVITY OF THE CRUDE METHANOLIC EXTRACT OF CALAMUS ROTANG L. LEAVES (ARECACEAE)
Medicinal plants abound with many phytochemicals that are effective in representing lots of pharmacological activities. The current study aimed at investigating the phytochemical and pharmaco-logical activity of crude methanol extract of Calamus rotang L. (CRME) leaves. The analgesic activity and thrombolytic activity were examined by the acetic acid-induced writhing method, while the clot lysis e...
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THE EFFECT OF KEREHAU LEAF EXTRACT (CALLICARPA LONGIFOLIA LAMK.) ON LIPID RATIOS AND AORTA HISTOPATHOLOGY OF MALE RATS OF WISTAR STRAIN
Ethanol extract of kerehau leaves is known to have anti-inflammatory and antioxidant activities with the potential to prevent atherosclerosis. This study aims to determine the ability of kerehau ethanol extract in reducing the lipid levels, the lipid ratios, and the number of foam cells in the blood vessel walls. This study employed in-vivo and ex-vivo experiments on male rats of Wistar strain ind...
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BIOLOGICALLY SYNTHESIZED SILVER NANOPARTICLES OF CURCUMA CAESIA ROXB. RHIZOME EXTRACT AND EVALUATION OF THEIR ANTIBACTERIAL ACTIVITY AGAINST MDR BACTERIA
Multidrug-resistant (MDR) bacterial infection is severe health concerns in the field of medicine. The researcher used green synthesized silver nanoparticles to overcome from MDR bacterial infection. Present study revealed successful synthesis of nanoparticles from Curcuma caesia aqueous rhizome extract by use of silver metal as a capping agent. Synthesized silver nanoparticles were identified by v...
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IN-SILICO MODELING AND VALIDATION OF L-GLUTAMINASE ENZYME, AN ANTICANCER DRUG USING WEB-BASED COMPUTATIONAL TOOLS
The L-Glutaminase enzyme is a therapeutic agent that can be employed for the treatment of human cancer, specifically lymphocytic leukemia. Microbes are exploited commercially to produce L-Glutaminase on a large scale. The L-Glutaminase is an economic anti-cancer drug and can be easily administered into patients. The L-Glutaminase is also employed in food industries in the processing of fermented f...
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A STRATEGY TO TREAT THE BREAST CANCER THROUGH INHIBITING THE OVER EXPRESSION OF PROTEIN ESTROGEN VIA SCHIFF BASE FUSED COUMARIN: AN IN-SILICO BASED SYNTHETIC APPROACH
Coumarin and its analogs have a wide range of attention in the treatment of hormone-dependent breast cancer by blocking the formation of estrogen through the inhibition of estrogen receptor. However, the Schiff bases are an important class of compounds with structural similarities of natural biological substances and also due to their presence of imine (-N=CH-), which have an impact on a biologica...
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SUSTAINED RELEASE MULTI-PARTICULATES FORMULATION OF STEREO-SELECTIVE MOLECULE OF KETOPROFEN BY FLUID BED PROCESSOR
The aim is to prepare sustained release multi-particulates dosage form of Dexketoprofen trometamol, which is the active isomer of ketoprofen. Utilization of active moiety with minimum drug dose and administration frequency sustained-release multi-particulates dosage form is explored. Sustained release pellets of the dexketoprofen trometamol were developed by the fluidized bed technology, in which ...
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FORMULATION AND PHYSICAL EVALUATION OF GLUCOCORTICOID LOADED TEA TREE OIL NANOEMULSION: A SUMMARIZED TECHNICAL NOTE
Clobetasol propionate (CP) has anti-inflammatory, immunomodulatory, and anti-proliferative activity. The current work aimed to prepare and evaluate the nanoemulsions of CP loaded tea tree oil (TTO) would be stable nanoemulsion. Clinical use of CP is restricted to some extent due to its poor permeability across the skin. So, to increase its permeation across the skin, microemulsion based formulatio...
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QSAR STUDIES, SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRAZOLE DERIVATIVES CONTAINING THIOUREA AS TYROSINE KINASE INHIBITORS: AN APPROACH TO DESIGN ANTICANCER AGENTS
A series of pyrazole derivatives designing for potential EGFR kinase inhibitors have been discovered. Some of them exhibited significant EGFR inhibitory activity. Compound 3-(4-Amino-phenyl)-5-(3-nitro-phenyl)-4, 5-dihydro-pyrazole-1-carbothioic acid amide (AP-2) displayed the most potent EGFR inhibitory activity. The QSAR analysis of a set of these compounds tested for growth inhibitory activity ...
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