9.
The increasing demand for natural, low-calorie sweeteners has driven innovation beyond first-generation plant derived glycosides. While advanced steviol glycosides such as rebaudioside M have achieved commercial success, mogrosides from Siraitia grosvenorii and Siamenoside I from Siraitia siamensis are emerging as promising next-generation monk fruit sweeteners. These cucurbitane type triterpene g...
Indra Prakash *, Canan Tari, Gil Ma, Juvenal Higiro and Christopher Mercogliano
Flavor & Ingredient Research and Applications, The Coca-Cola Company, One Coca-Cola Plaza, Atlanta, GA 30313, Atlanta, Georgia, USA.
DOI: 10.13040/IJPSR.0975-8232.17(9).2652-59
2652-2659
10.
Breast cancer is the most common malignancy affecting women worldwide. Molecular docking is an important computational technique in drug discovery interaction between ligands and target proteins. In present study docking analysis binding affinity of 51 heterocyclic ligands against the breast cancer target protein NUDT5 (PDB ID:5NWH) are nucleotide- metabolizing enzymes (NUDIX) hydrolases. It p...
R. Govinda Rajan, S. Udhaya Vani, A. P. S. M. Krishna *, Ch. Dhanalakshmi Manimadhuri, G. Harika and S. K. Nujhat Aara
Department of Pharmaceutical Chemistry, Hindu College of Pharmacy, Guntur, Andhra Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.17(9).2660-75
2660-2675
11.
Background: India is one of the highest TB burden countries with an annual incidence 199 TB cases/100,000 population and the estimated death rate in the year 2023 among all forms of TB was 23/100,000 population. The variables like undernutrition or malnutrition at treatment initiation, low BMI, presence of comorbidities and severe stunting were associated with unfavourable TB treatment outcomes. M...
Ramesh Verma, Achchhesh Singmar *, Meena, Meenakshi Kalhan, Vinod Chayal, Himani, Meenu Yadav, Amandeep Kaur, Amit Kumar, Sonali Singla and Diksha Kataria
Department of Community Medicine, Pt. B. D. Sharma PGIMS, Rohtak, Haryana, India.
DOI: 10.13040/IJPSR.0975-8232.17(9).2676-84
2676-2684
12.
High altitude hypoxia exposure contributes in oxidative stress, leading to cellular damage and disrupting normal cellular function. The aim of the present study was to assess the effect of beetroot juice (BRJ) supplementation on oxidative stress, inflammation and neuroendocrine changes imposed in individuals upon high altitude exposure. This was a randomized controlled, longitudinal study conducte...
Karishma Dohare, Subhasis Bose, Divya Singh and Praveen Vats *
Defence Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, Delhi, New Delhi, India.
DOI: 10.13040/IJPSR.0975-8232.17(9).2685-94
2685-2694
13.
A stable multicomponent crystalline phase involving an anti-cancer agent (5-Fluorouracil, 5-FU) and an immunomodulator (Levamisole, LM) was developed through a systematic descriptor-guided screening workflow. Binary 5-FU/LM combinations failed to yield new solid phases, as assessed by Fourier Transform Infrared Spectroscopy (FTIR), a finding rooted in the complete absence of hydrogen bond donor fu...
Prashant Kumar and Kaushal Kumar *
Department of Pharmacy, Mahatma Jyotiba Phule Rohilkhand University, Bareilly, Uttar Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.17(9).2695-04
2695-2704
