Lornoxicam (chlortenoxicam) is a non steroidal anti- inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. It is available in oral and parental dosage formulation. Lornoxicam is a Yellow or slightly yellow powder. It is slightly soluble in water, soluble in hydrochloric acid, slightly soluble in methanol. A simple spectrophotometric method was ...
Cordia dichotoma known as lasura, lisora, is a commonly known herb in Indian system of medicine to treat various disorders including diabetes mellitus without any scientific evidences. Therefore this study was designed to investigate in vivo hypoglycemic and antidiabetic potential of methanol extract of fruits of Cordia dichotoma in glucose loaded animals and alloxan induced diabetic animals. In b...
This study evaluated the in vitro antioxidant and cytotoxic potential of methanolic extract of the rhizome of Costus speciosus (Zingiberaceae). The different antioxidants assays including total antioxidant activity, DPPH, nitric oxide (NO) scavenging, total phenolic content and flavonoid content were studied. Costus speciosus exhibited potent total antioxidant activity which was expressed as an eq...
Needle-free injection systems are novel ways to introduce various medicines into patients without piercing the skin with a conventional needle. Needle-free technology offers the very obvious benefit of reducing patient concern about the use of needle. Needle free injection gives very effective injections for a wide range of drugs and bioequivalent to syringe and needle, results in less pain, a...
DEVELOPMENT AND APPLICATION OF DIFFERENCE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF FEBUXOSTAT IN TABLETS
A simple, rapid, sensitive and cost effective difference spectrophotometric method have been developed for the determination of Febuxostat in its tablet dosage form. The method is based on the induced spectral changes upon changing the pH of the medium that differ in their UV spectra. Difference spectrum, obtained by keeping Febuxostat in 0.1N NaOH in reference cell and same in 0.1N HCl in sampl...
ASSESSMENT OF ANALGESIC AND ANTIBACTERIAL ACTIVITY OF PREMNA INTEGRIFOLIA LINN. (FAMILY: VERBENACEAE) LEAVES
Premna integrifolia Linn. (Family: Verbenaceae) is a medicinal plant which is traditionally used against a number of diseases including inflammatory condition. On the scientific basis of traditional uses, the ethanolic extract of leaves of Premna integrifolia Linn. was assessed for its possible analgesic and antimicrobial activity. The analgesic activity of the sample was studied using acetic acid...
Tinospora cordifolia (Thunb.) Miers, (Guduchi) is an evergreen perennial climber. This deciduous and dioecious plant belongs to the family Menispermaceae. It is a plant of significant medicinal importance in the Indian system and designated as Rasayana. Its efficacy has been also recognized by the modern system of medicine. The whole plant is used medicinally however; the stem is approved for us...
ANTIRHEUMATOID ACTIVITY OF AQUEOUS EXTRACT OF PIPER LONGUM ON FREUNDS ADJUVANT-INDUCED ARTHRITIS IN RATS
Aqueous extract of the fruits of the plant Piper longum was studied for their Anti rheumatoid activity in Freunds Adjuvant Induced Arthritis Rats with the dose of 200 and 400 mg/kg p. o. The administration of extract reported significant reduction in paw swelling on 4th, 8th, 14th and 21st day after sub-plenter administration of Complete Freunds adjuvant. The paw swelling was measured as a volume ...
The manufacture of bi-layer tablets, produced by the sequential compaction of loose powder layers has recently become of increased interest within the pharmaceutical industry due to the tailored release profiles of active ingredients that may be obtained. In a bi-layer configuration, the immediate release layer of the bi-layer tablet has worked as the loading dose and the sustained release layer h...
Fertility control is an issue of global and national health concern, many study have been done for the male contraception. The use of medicinal plants in different sorts of disease including fertility problem is widespread throughout the world. Though considerable progress has been made the development of highly effective, acceptable and reversible methods of contraception among females, progress ...