L-Asparaginase (E.C. 184.108.40.206.), also known as L-asparagine amidohydrolase is the enzyme with anti-tumor activity and is well accepted as a chemotherapeutic agent against the acute lymphoblastic leukemia and lymphosarcoma. This article has briefly touched nearly all the industrial and clinical aspects of L-Asparaginase and provides the recent update of the topic. The article includes a brief introd...
DASAPUSHPAM: THE TRADITIONAL USES AND THE THERAPEUTIC POTENTIAL OF TEN SACRED PLANTS OF KERALA STATE IN INDIA
The Western Ghats of Kerala is famous for its medicinal plant wealth and the tradition of indigenous system of therapy, specifically the Ayurveda. Dasapushpam constitute a group of ten potential herbs which are culturally and medicinally significant to the people of Kerala in India. They are a group of ten herbs with which the ladies decorate their hairs and dance the Thiruvathira Kali on the day ...
ASSESSMENT OF DRUG USE PRACTICES AND COMPLETENESS OF PRESCRIPTIONS IN GONDAR UNIVERSITY TEACHING REFERRAL HOSPITAL
Background: Rational drug use is a tool through which safe, effective and economic medication is provided. Rational prescribing ensures adherence to treatment and protects drug consumers from unnecessary adverse drug reactions. Rational dispensing on the other hand, promotes the safe, effective and economic use of drugs. Objectives: The aim of this study was to assess drug use practices and com...
GC/MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF DIETHYL ETHER FRACTION OF METHANOLIC EXTRACT FROM THE STEM BARK OF ANNONA SENEGALENSIS PERS.
The Diethyl ether fraction of the Methanolic extract of Annona senegalensis (Pers) stem bark was prepared in yield of (0.16%). Preparative Thin Layer Chromatography analysis of the fraction resulted in the identification of two spots with antimicrobial activity. Subsequent GC/MS analysis of these spots resulted in the identification of ten components (spot one) and fourteen components (spot two). ...
Legumes are plants in the family Fabaceae characterized by seeds in pods that are often ediblethough sometimes poisonous. The nutrient content (protein, carbohydrate and micronutrients) of legumes contribute to address under-nutrition, especially protein-calorie malnutrition among children and nursing mothers in developing countries where supplementing cereal-based diets with legumes is suggested ...
Co-crystals consists of API and a stoichiometric amount of a pharmaceutically acceptable co-crystal former. Pharmaceutical Co-crystals are nonionic supramolecular complexes and can be used to address physical property issues such as solubility, stability, and bioavailability in pharmaceutical development without changing the chemical composition of the API. Cocrystal is a crystalline entity formed...
Microemulsions are clear, stable, isotropic mixtures of oil, water and surfactant, frequently in combination with a cosurfactant. Microemulsions act as potential drug carrier systems for oral, topical, and parenteral administration. They offer the advantage of spontaneous formation, ease of manufacturing and scale-up, thermodynamic stability, and improved drug solubilization and bioavailability. P...
Oral route is the easiest and most convenient route of drug administration, being non invasive and cost effective, thereby leading worldwide drug delivery market. But major problem encountered in oral formulations (as estimated more than 50 % of oral formulations are found to be poorly aqueous soluble), is low bioavailability, giving rise to further problems like, high inter and intra subject vari...
Worldwide diabetic patients are very common. This paper studies spread of diabetes in human living in Lahore, Pakistan. Data is collected from two local hospitals of Lahore and TOPSIS is applied to draw the results of the study. The study points out the people who are more likely to have diabetes due to various parameters like age, weight, height, body mass index (BMI), systolic blood pressure (SB...
Cassia fistula Linn. (Family: Caesalpinaceae), commonly known ‘Sonali’ or ‘Bandarlati’, has been used in different traditional system of medicines for various ailments since ancient times. Cassia fistula grows throughout in Bangladesh and in many other Asian countries such as India, China, Hong Kong, Philippines, Malaysia, Indonesia, and Thailand. This article aims to provide a comprehensi...