Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ANTIBACTERIAL ACTIVITY OF LIBYAN SEAWEED EXTRACTS
Marine organisms are potentially prolific sources of highly bioactive secondary metabolites that might represent useful leads in the development of new pharmaceutical agents. The Libyan marine biodiversity including macroalgae remains partially unexplored in term of their potential bioactivities. Method: The phytochemical analysis of the alcoholic extracts of some commonly occurring seaweed Cystos...
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NUTRITIONAL AND MEDICINAL VALUES OF SELECTED WILD CUCURBITS AVAILABLE IN SIMILIPAL BIOSPHERE RESERVE FOREST, ODISHA
Cucurbitaceae commonly known as “Guard family” is distributed throughout India. Most of them, are perennial climbers with attractive flowers. The family includes plants having food as well as medicinal values. The species of the family are collectively known as cucurbits. They grow wild as well as cultivated throughout the state in Odisha in general and Similipal Biosphere Reserve (SBR) forest...
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CHEMICAL CONSTITUENTS OF THE ANTIDIABETIC PLANT RAVENALA MADAGASCARIENSIS
Ravenala madagascariensis Sonn. is one of the most popular medicinal plants in Madagascar, India and several African countries. It is used in the treatment of many diseases, and particularly in those of diabetes. The duration of treatment, often for life, and its relatively high cost for certain social categories, constrain more and more patients to use this plant. Its chemical constituents were s...
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EFFECT OF NANOCURCUMIN PARTICLES PREPARED BY TOP-DOWN METHOD ON CCl4-INDUCED HEPATIC FIBROSIS MICE
Curcumin, a hydrophobic polyphenolic compound derived from the rhizome of the herb Curcuma longa, possesses a wide range of biological applications including anti-cancer. Nanocurcumin particles were prepared by top-down method as its can improve hydrophilic and increase bioavailability. As a result, curcumin concentration was yielded up to 10% (w/w), and the particle size was defined less than 1,0...
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A VALIDATED RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF METRONIDAZOLE AND CIPROFLOXACIN HYDROCHLORIDE IN PHARMACEUTICAL DOSAGE FORM
A reversed-phase-liquid chromatographic (RP-HPLC) method was developed for the determination of Metronidazole (MTZ) and Ciprofloxacin HCl (CPX) in their bulk drug and marketed formulations. The separation was carried out using a mobile phase of 25mM Potassium dihydrgen phosphate buffer of pH 3.0 consisting of 0.15%v/v Triethylamine, 0.1% Phosphoric acid and Methanol in the ratio of( 60:40v/v). T...
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CARDIO-VASCULAR ACTIVITY OF GYNURA PROCUMBENS MERR. LEAF EXTRACTS
Gynura procumbens has been known to be used as traditional medicine for treatment of kidney disease, rashes, fever and for hypertension. We report here the cardiovascular effects of the different ethanol (95%, 75%, 50%, 25% v/v) and water extracts using in vitro studies. Gynura procumbens leaves extract was prepared by maceration process. The cardiac effects (chronotropic and ionotropic) of each e...
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IN-VITRO EVALUATION OF ANTIOXIDANT ACTIVITY AND TOTAL PHENOLIC CONTENT OF TYLOPHORA INDICA (BURM F.) MERILL
Tylophora indica is a perennial climbing plant native to India, found in plains, forests, hills of southern and eastern India. The portions of plant used medicinally are leaves. The Total phenolic content of methanolic leaves extract was estimated by Folin-Ciocalteu assay method, and was found to be 0.160 mg/CE/g (Catechine Equivalent per gram). However, antioxidant activity of methanolic leaves e...
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ANTIOXIDANT EFFECT OF NARINGIN ON NICKEL-INDUCED TOXICITY IN RATS: AN IN VIVO AND IN VITRO STUDY
The aim of the study was to evaluate the circulating antioxidant such as vitamin C, vitamin E and GSH in nickel (Ni) induced toxicity in rats and in vitro free radical scavenging assay. In this investigation nickel sulfate (20 mg/kg body weight (b.w.) was administered intraperitoneally (i.p.) for 20 days to induce toxicity. Naringin was administered orally (80 mg/kg body weight) for 20 days with i...
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MECHANISM OF ACTION OF ANTICONVULSANT DRUGS: A REVIEW
Epilepsy is a neurological disorder characterized by excessive electrical discharge in brain, which causes seizures. The therapeutic strategy in countering epilepsy involves reducing neuronal excitability through different mechanistic pathway. Most therapeutics currently used in the treatment of epilepsy is either directed towards blocking voltage-gated sodium and calcium channels or potentiating ...
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SIMULTANEOUS ESTIMATION OF MOXIFLOXACIN HCl AND BROMFENAC SODIUM IN EYE DROPS BY SPECTROPHOTOMETRIC METHODS
Moxifloxacin Hydrochloride is a fluorinated quinolone antibacterial and Bromfenac Sodium is a non-steroidal anti-inflammatory. The combination formulation is used for the treatment of the reduction of post operative inflammatory conditions of the eye. Three new, simple, accurate and precise UV spectrophotometric methods have been developed and validated for the simultaneous determination of Moxifl...
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