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T3 IS AS GOOD A POINTER OF CREATINE KINASE LEVELS IN EUTHYROIDS AS T4 IS IN HYPOTHYROIDS
Aim: Hypothyroidism is one of the commonest metabolic diseases which afflicts females more than males and is often associated with myopathy. Reports on relationship of muscle-markers with thyroid hormones in the (a) euthyroid population in general and (b) hypothyroid population in India are scarce. Materials and Methods: A randomized case-control study on the female population for which 60 hypothy...
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MARKETING OF ANTI-ULCER DRUGS TO THE END-USERS
The paper focuses on different marketing techniques in Pharmaceutical Industry with reference to anti-ulcer drugs. This is an industry where a number of characteristics like, efficacy, quality and safety matters while delivering a product (i.e. the drug). This study comes up with drug development and the various aspects of bringing the product to the market. Secondly, it deals with determining the...
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1595
EVALUATION OF BIOACTIVITIES OF TWO POLYHERBAL FORMULATIONS FOUND IN SRI LANKAN AYURVEDIC TREATMENTS
Commercially available two polyherbal formulations (Chandra Kalka and Sharkaradi Kalka) were collected from local market. The objective of this study was to determine the Total Phenolic Content (TPC) , Total Flavonoid Content (TFC) of these two ‘Kalkas’ and to investigate the existence of antioxidant, anti-inflammatory, antibacterial and anti-tyrosinase activities. Total phenolic content and t...
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PRELIMINARY PHYTOCHEMICAL, ANTI-BACTERIAL, ANALGESIC, ANTI-DIARRHOEAL AND CYTOTOXIC ACTIVITY OF METHANOLIC EXTRACT OF POLYALTHIA SUBEROSA LEAVES
The MeOH extract of leaves of Polyalthia suberosa Roxb. (Annonaceae) was screened for its antibacterial, analgesic, Antidiarrhoeal and cytotoxic activities. The extract showed moderate anti-bacterial activity against Vibrio cholerae, Sheigella sonnei, Staphylococcus aureus, Staphylococcus epidermidis and Streptococcus saprophyticus. It also produced significant (P<0.01) writhing inhibition in a...
4271
1956
TRAINING NEED ASSESSMENT OF DISPENSING PHARMACISTS IN MAHARASHTRA
Background: A crucial part of Continuing Education is Training needs assessment (TNA). TNA assists in design and development of relevant educational courses and training modules, which are valuable for health care professionals to improve their knowledge and skills in accordance to latest developments in the field of clinical practices. Methods: A qualitative study was designed constituting Focuse...
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1571
VOLTAMMETRIC DETERMINATION OF RUPATADINE AT GRAPHENE MODIFIED GLASSY CARBON ELECTRODE
Electrochemical behavior of rupatadine, an anti-allergic drug was studied at graphene modified glassy carbon electrode in Britton-Robinson buffer (pH 6.5) by square wave voltammetry (frequency, 50 Hz; amplitude, 0.02 V; step potential, 0.005 V) and cyclic voltammetry (scan rates, 20-100 mV/s) techniques. Cyclic voltammetry revealed the oxidation of rupatadine corresponding to N-dealkylation which ...
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1596
SYNTHESIS, CHARECTERIZATION AND ANTIMICROBIAL ACTIVITY OF 5-METHYL -2, 4-DIHYDRO-3H-PYRAZOL-3-ONE-4-(4-SUBTITUTED) BENZYLPIPERAZINE DERIVATIVES
Synthesis of 6-Methyl-2, 4-dihydro-3H-pyrazol-3-one- 4- (4-substituted) Benzylpiperazine derivatives IVP a-e was carried out by bromination of Ethyl aceto acetate (I) with KBr. The reaction was carried out in the presence of Hydrochloric acid and tolune to produce Bromo-ethyl aceto acetate (II), it is further condensed with substituted Benzylpiperazines in presence of ethanol to obtain condensed c...
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MOLECULAR DOCKING STUDIES OF CANTHIN-6-ONE FROM SIMAROUBA GLAUCA AGAINST EGFR TYROSINE KINASE
In recent years, in silico approaches have been predicting novel drug targets. The objective of this study was to analyze the inhibitory action of canthin-6-one alkaloid by computational docking studies. For this study, natural metabolite canthin-6-one isolated from Simarouba glauca was used as ligand for molecular interaction. The crystallographic structure of molecular target Epidermal Growth Fa...
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1915
ISOLATION OF STARCH FROM CURCUMA LONGA L. AND ITS CHARACTERIZATION
The present work was aimed to evaluate the different properties of turmeric starch. Starch has been an endless subject of research for many years. It is an inexpensive, readily available compounds with considerable applications in the food as well as non-food. Turmeric starch was isolated from fresh rhizomes of Curcuma longa L. and Curcuma Caesia (Zingiberaceae). In this article, we established an...
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1902
EFFECT OF AZADIRACHTA INDICA ON HYPERGLYCEMIA INDUCED OXIDATIVE STRESS IN ALLOXAN DIABETIC RAT BRAIN
The present study evaluates antidiabetic effect of A. indica leaf extract (AILE) and A. indica bark extract (AIBE) on antioxidant enzymes in the brain of alloxan diabetic rats and compared with insulin treatment. The oral effective dose of A. indica leaf (500mg/Kg body weight) and A. indica bark (100mg/Kg body weight) was given once daily for 21days to separate groups of diabetic rats. At the end ...
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