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EVALUTION OF ANTI-DIABETIC ACTIVITY OF METHANOL EXTRACT OF DIGERA MURICATA (L) MART IN ALLOXAN INDUCED DIABETIC RATS
Digera muricata (L.) Mart (Amaranthaceae) commonly known as Cancali soppu widely used in traditional system of medicine for the treatment of diabetes mellitus In the present study, Methanol extract of Digera muricata(MEDM) leaves were subjected to phytochemical investigation and evaluated for antidiabetic activity in alloxan induced diabetic rats. MEDM (100, 200 mg/kg) and Glibenclamide (3mg/k...
4319
1937
EFFECT OF THE PREGNANCY PERIOD PREPARATION CLASSES ON THE NUTRITIONAL BEHAVIOR OF THE POSTPARTUM PERIOD
Postpartum period is an important step because the mother's body needs to heal and recover, after pregnancy period and childbirth. So taking good care and a balanced diet in the postpartum period, plays an important role in the women's health. Thus, training of nutrition is so necessary at this period. The aim of this study was an evaluation the effect of the pregnancy period preparation classes o...
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1542
DEVELOPMENT & EVALUATION OF SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF ATOVAQUONE IN PHARMACEUTICAL DOSAGE FORM
A very simple and selective U. V. Method was developed and validated for the estimation of Atovaquone in pure form and the nanosuspension. The adequate drug solubility and maximum assay sensitivity was found in 8.00 Ph IPA Phosphate Buffer in 40:60 ratios v/v. The absorbances were measured at the λmax. of 494 nm in the wavelength range of 200-800 nm. The linear calibration range was found to be 2...
4318
2106
KNOWLEDGE AND ATTITUDE OF PRIMARY CARE PHYSICIANS TOWARD USE OF HERBS AS MEDICINE IN AL-WAZARAT HEALTH CENTER, PRINCE SULTAN MILITARY MEDICAL CITY, RIYADH, SAUDI ARABIA
Introduction: Herbs are the second most commonly used form of complementary and alternative medicine by public. The uses of medicinal herbs continue to increase worldwide. However, clinicians generally have limited knowledge and confidence about using of herbs in medicine. Therefore, this research aimed to assess the level of knowledge and attitude of primary care physicians toward use of medicina...
4318
1547
DEVELOPMENT AND VALIDATION OF HPLC METHOD FOR DETERMINATION OF CERITINIB IN RABBIT PLASMA USING PDA DETECTOR
A rapid, sensitive and reproducible HPLC method was developed and validated for the quantification of Ceritinib in rabbit plasma using PDA detector at wave length 264 nm. The method was developed using Dasatinib as internal standard (IS). Ceritinib is a selective and potent inhibitor of anaplastic lymphoma kinase (ALK) indicated in the treatment of non-small cell lung cancer (NSCLC). The Ceritinib...
4318
1662
PHYTOCHEMICAL PROFILING AND ANTICANCER ACTIVITY OF DRAGON FRUIT HYLOCEREUS UNDATUS EXTRACTS AGAINST HUMAN HEPATOCELLULAR CARCINOMA CANCER (HEPG-2) CELLS
To investigate the phytoconstituents and anticancer potential followed by apoptotic studies of H. undatus fruit extracts on HepG-2 cells. Qualitative phytochemical profiling and anti-proliferation activity of Aqueous, Chloroform, Ethyl acetate, Hexane, and Methanol extracts of dragon fruit pulp was carried out. Based on the results of anti-proliferation studies, methanol extract was taken further ...
4318
1574
ANTI-TUMOUR POTENTIAL OF ACTIVE COMPOUNDS (POLYSACCHARIDES) OF WILD MUSHROOMS FROM RAJOURI DIST. OF JAMMU & KASHMIR, INDIA
Natural products have been closely linked through the use of traditional medicines and natural poisons. Mushrooms have an established history of use in traditional oriental medicine, where most medicinal mushroom preparations are regarded as a tonic, that is, they have beneficial health effects without known negative side-effects and can be moderately used on a regular basis without harm. Mushroom...
4317
1773
LIQUISOLID TECHNIQUE FOR ENHANCEMENT OF DISSOLUTION PROPERTIES OF FENOFIBRATE
The in vitro dissolution property of slightly water soluble Fenofibrate (FN) was improved by exploring the potential of Liquisolid system (LS). The in vitro release pattern of LS compacts and directly compressed tablets were studied using USP-II apparatus. Different LS compacts were prepared using a mathematical model to calculate the required quantities of powder and liquid ingredients to produce...
4317
1955
DEVELOPMENT OF QUALITY STANDARDS OF VATARI CHURNA: A POLYHERBAL FORMULATION
India is a landmark for traditional system of medicine from past few centuries. Most of the medicines are effective but only one major drawback is lack of standardization. So, there is a need to develop a standardization technique to mingle this system of medicine in the main stream of health science. Standardization of herbal formulations is essential in order to assess the quality of drugs, base...
4316
1642
INVITRO ANTIOXIDANT STUDY AND SEARCH FOR A NOVEL BIOACTIVE COMPOUND FROM LEAVE FRACTIONS OF CANTHIUM COROMANDELICUM (BURM.F.) ALSTON
Background: Plants are enriched with various types of phytoconstituents present in the form of secondary metabolites that ensure its medicinal value. Keeping this in view, the present investigation was carried out focusing on its antioxidant property that may mainstay of exploring other therapeutic potency. Hence, phytochemical investigation followed with antioxidant property was evaluated in the ...
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2277