Most Popular
IN-VITRO ANTHELMINTIC ACTIVITY OF ENICOSTEMMA LITTORALE BLUME
The World Health Organization estimates that a staggering two billion people harbor parasitic worm infections. Parasitic worms also infect livestock and crops, affecting food production with a resultant economic impact. Despite this prevalence of parasitic infections, the research on antihelmentic drug is poor. As per WHO, only few drugs are frequently used in the treatment of helminthes in human ...
3074
1491
ANTIMYCOBACTERIAL ACTIVITY OF FOLIOSE LICHENS ON PLANT AND ANIMAL PATHOGENS
Antimicrobial effects of different extracts of lichens were evaluated in this study. Acetone extract of Heterodermia boryi have shown maximum inhibitory activity against Escherichia coli (22mm) followed by Staphylococcus aureus (21mm)and Pseudomonas fluorescenes (20 mm). Among fungi, diethyl ether extract gave desirable sensitivity pattern against Pestalotia foedans was very sensitive (21mm) follo...
3073
1161
STUDIES ON PHTHALIC ACID-PROPANE-1, 2-DIOL-GLYCEROL CO-POLYESTER AS AN ENTERIC COATING MATERIAL
Enteric coating material that, was synthesized in the laboratory and applied to a tablet and also drug release profile was investigated. A polymeric material - Phthalic acid propane-1,2 diol-glycerol co-polyester (PPGC) was synthesized from phthalic acid and propane-1, 2-diol with 5% glycerol of total weight as a crosslinking agent using Dean-Stark apparatus with Ferric Chloride as catalyst and o-...
3073
1196
EXPLORING THE ANTIMICROBIAL PROPERTIES OF ARTEMISIA ANNUA DURING DIFFERENT FLOWERING STAGES
Many of the plants used to treat certain diseases because they have shown antimicrobial activity. In this case, many studies have conducted on antimicrobial activity of Artemisia annua. The crude extracts obtained from Artemisia annua L. (Asteraceae) were investigated for their antibacterial activity by using agar well diffusion assays against three bacterial species (Escherichia coli, Bacillus su...
3072
977
SCREENING OF INDIGENOUS MEDICINAL PLANTS FOR THEIR ACARICIDAL ACTIVITY AGAINST CATTLE TICKS UNDER IN VIVO CONDITION
The acaricidal activity of leaf extracts of Annona squamosa, Azadirachta indica and Calotropis procera were tested against the cattle ticks under in vivo condition. Plants were extracted with methanol and water and the extracts were tested against the cattle ticks under in vivo condition. The aqueous and alcoholic extracts of A. indica showed maximum mortality rate of ticks followed by A. squamo...
3072
1258
DOSE DEPENDENT CARDIAC EFFECTS OF DOXORUBICIN IN WISTAR RATS: A BIOCHEMICAL AND HISTOPATHOLOGICAL ANALYSIS
Although doxorubicin is used widely in animal models to induce cardiotoxicity, serial dose-dependent cardiac effects have not been investigated in experimental animal models to date. Therefore, the objective of this study was to find out the dose-dependent changes of doxorubicin-induced acute cardiotoxicity, both biochemically and histopathologically in Wistar rats. Wistar rats were divided into n...
3072
1136
DESIGN AND EVALUATION OF RIMONABANT LOADED SODIUM ALGINATE-GUAR-GUM MICROSPHERE FORMULATION
Rimonabant is an anti-obesity drug which acts as Cannabinoid-1 receptor antagonist. Its main avenue of effect is reduction in appetite. The drug was formulated in the form of Sodium Alginate – Guar gum microspheres following ionotropic gelation method to reduce its dose related side effects. A detailed study of physical and chemical parameters including percentage drug loading and cumulative dru...
3071
1196
PROFILE OF ANTICANCER AND RADICAL SCAVENGING ACTIVITIES OF STEROIDS FROM STEMS OF POLYGONUM PULCHRUM
Five steroids have been isolated and identified from methanol extracts of stems of Polygonumpulchrum (Bambu-bambu, Tolakinese, a South East Sulawesi Ethnic), namely; (1) sigmasta-4, 25-diene-3,6-diol; (2) 6β-hydroxystigmasta-4.22-dien-3-one, (3) stigmasterol, (4) stigmasta-4.22-dien-3-on, and (5) ergosterol peroxide. The isolation was worked by using chromatography method including thin layer c...
3071
1650
BRASSICA OLERACEA: A POTENT ANTIOXIDANT THERAPEUTIC IN HEALTH AND DISEASES
Oxidative stress contributes towards initiation and progression of hepatic damage in a variety of liver disorders (e.g. Hepatitis C, Hepatitis B, non alcoholic fatty liver disease amongst others). Hence, there is a great demand for the development of agents with potent antioxidant effect. There are various plant derived products which act as antioxidants. The aim of the present investigation is to...
3071
1160
PRESCRIPTION PATTERN AND USE OF ANTIBIOTICS AMONG PEDIATRIC OUT PATIENTS IN RAJSHAHI CITY OF BANGLADESH
Excessive antimicrobial use leads to adverse drug effects, thus increased healthcare costs and promoting the emergence of antimicrobial resistance worldwide. The aim of the study was to evaluate the prescription pattern of antibiotics in pediatric outpatients at private hospitals in Rajshahi city of Bangladesh. WHO / INRUD prescribing indicators were used for the analysis of prescription pattern. ...
3071
1145