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FREQUENCY OF MILD AND SEVERE DEPRESSION CONSIDERING THE GENDER AND BLOOD GROUPS AMONG MEDICAL STUDENTS OF INTERNATIONAL MEDICAL AND TECHNOLOGICAL UNIVERSITY (IMTU), DAR ES SALAAM
Objective: Study to elucidate the relation between depression, gender and blood groups. Methods: The study was prepared on 279 medical students of IMTU, who have spent more than four months in the medical school. A Performa for testing depression scale was given to the students. Blood groups and gender were analyzed. Results: It was evident that few blood groups like A and O shown significan...
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EVALUATION OF ANTICONVULSANT ACTIVITY OF SEMECARPUS ANACARDIUM (LINN.) NUT EXTRACT
The present study was undertaken to evaluate the locomotor effect of chloroform extract of Semecarpus anacardium (Linn.) (CHSA) by using photoactometer. Its anticonvulsant property was tested against maximal electroshock (MES)-induced convulsion (MESIC), pentalenetetrazol (PTZ)-induced convulsion (PTZIC), strychnine-induced convulsion (SIC), picrotoxin-induced convulsion (PIC), isoniazid (INH)-ind...
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ATTENUATION OF HYPERGLYCEMIA AND OXIDATIVE STRESS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS BY AQUEOUS EXTRACT OF AVERRHOA BILIMBI LINN FRUITS
In the present study, the antidiabetic and antioxidant effect of aqueous extract of Averrhoa bilimbi Linn (ABAE) fruits were evaluated. Diabetes mellitus was induced in male Sprague Dawley rats by a single intraperitoneal injection of streptozotocin (40 mg/kg body weight). Oral administration of aqueous extract of Averrhoa bilimbi Linn (ABAE) (50mg/kg body weight) and metformin (100 mg/kg body wei...
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FAMILY SELF MEDICATION IN CHILDREN ATTENDING A TERTIARY CARE HOSPITAL IN NORTHEAST INDIA
This study was undertaken to determine the prevalence and determinants of family self-medication in children in northeast India. A validated structured interview schedule was used in 487 caregivers of children attending the out-patient department and in-patient ward of the department of pediatrics, Regional Institute of Medical Sciences, Imphal, India. The study schedule included questions related...
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VISIBLE SPECTROPHOTOMETRIC DETERMINATION OF TELMISARTAN FROM URINE
The proposed method is new, simple, sensitive, reproducible, economical, accurate and precise and can be successfully applied in estimation of Telmisartan (Telmi) from urine. This method can find applications in clinical studies and therapeutic drug monitoring. This method of colorimetric estimation of telmisartan from urine is based on the formation of yellow colored chromogen when it is reacted ...
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ASSESSMENT OF KNOWLEDGE, ATTITUDE AND PRACTICE OF PRESCRIBING FIXED DOSE COMBINATIONS AMONG POSTGRADUATE MEDICAL STUDENTS – A CROSS SECTIONAL SURVEY
Objective: To evaluate the knowledge, attitude and practice, regarding Fixed Dose Combinations (FDCs) among Postgraduate medical students of Bangalore Medical College and Research Institute, Bengaluru. Materials and methods: The questionnaire based study was conducted among 150 Postgraduate medical students of BMCRI, Bengaluru. The data obtained was analyzed using descriptive statistics. Results: ...
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RESEALED ERYTHROCYTES AS A POTENTIAL DRUG CARRIER SYSTEM
Novel drug delivery system has been introduced to overwhelm the drawback of fluctuating drug levels associated with conventional dosage forms. Out of various cellular carrier systems, erythrocytes (red blood cells, RBC) have been the most widely investigated and found to possess great potential for the delivery of drugs and drug-loaded microspheres. These cellular carriers, having remarkable bioco...
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NOVEL 2 – AMINO – N’ – (2-OXOINDOLIN – 3 – YLIDENE) BENZO [d] OXAZOL – 5 -CARBOHYDRAZIDES AS ANTI-INFLAMMATORY AGENTS
In the present work , novel 2-Amino-N'-(2-oxoindolin-3-ylidene) benzo[d]oxazole-5-carbohydrazides were synthesized and evaluated for In-vivo anti-inflammatory activity by carragenan induced rat paw edema method and were known to exhibit promising anti-inflammatory activity at a dose of 30mg/kg bw. Compounds D2, D3, D5 and D8 were found to be comparatively potent with the standard Indomethacin....
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EVALUATION OF BRONCHIAL SMOOTH MUSCLE RELAXANT ACTIVITY OF FLUPIRTINE IN EXPERIMENTALLY INDUCED ASTHMA IN GUINEA PIGS
Objectives: The study aimed at evaluating the broncho-relaxant effect of the test drug Flupirtine in experimentally induced Asthma in Guinea pigs & compares its efficacy with the Standard. Materials and Methods: Guinea pigs of both sexes weighing around 350-400 gm were randomly divided into 3 groups of 6 animals each. Groups were categorised into Control, Standard and test groups. Animals serv...
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MOLECULAR MODELLING AND MOLECULAR DYNAMICS STUDIES OF SPECT PROTEIN OF PLASMODIUM FALCIPARUM AND IN SILICO SCREENING OF LEAD COMPOUNDS
Malaria has been a major life threatening mosquito borne disease. Unavailability of any effective vaccine and recent emergence of multi drug resistant strains of malarial pathogen Plasmodium falciparum continues to cause persistent deaths in the tropical and sub-tropical region. As a result, there is a growing demand for new targets for more effective anti-malarial drugs. A novel microneme prot...
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