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MURRAYA KOENIGII MEDIATED SILVER NANOPARTICLE SYNTHESIS AND ITS ACTIVITY AGAINST ENTERIC PATHOGENS
Objective: The objective of this research was a synthesis of silver nanoparticles from Murraya koenigii leaves in which the particles were characterized by various techniques and to evaluate the potential antibacterial activity of synthesized nanoparticles against various human pathogens. Methods: Murraya koenigii aqueous extract of leaves were prepared by the Soxhlet method, and the bioactive com...
3996
2633
COMPARATIVE ANTIBACTERIAL STUDY OF DIFFERENT EXTRACT OF CLAVERIA ROSEA FRIES AGAINST GRAM NEGATIVE AND GRAM POSITIVE PATHOGENS
Objective: To compare the antibacterial activity of different solvent extract of Clavaria rosea. Method: Different solvent extract of Claveria rosea was prepared. Standard cultures of Escherichia coli (MTCC-1698), Klebsiella pneumoniae (MTCC-7028), Pseudomonas aeuroginosa (MTCC-1934), Salmonella typhi (MTCC-733), Xanthomonas campestris (MTCC-2286), Pseudomonas syringae (MTCC-1604) and Agrobacte...
3995
1372
EFFECT OF POLYMER IN RELEASE PROFILE OF EXTENDED RELEASE MATRIX TABLET OF ANTI-HYPERTENSIVE DRUG & TO STUDY IMPACT OF AGGLOMERATIVE PHASE OF COMMINUTION (APOC) METHOD ON DRUG RELEASE
The objective of this study is to develop extended release matrix tablet of antihypertensive drug benidipine hydrochloride (BH) and to study its drug release pattern. BH has mean elimination half-life is ~3 h and requires dosing every 4 - 5 h in order to maintain optimal relief and is used orally in the management of hypertension and angina pectoris, but this frequent administration produces side ...
3995
2102
SYNTHESIS AND SPECTRAL STUDIES OF Ni(II) COMPLEXES WITH 2-HEPTANONESEMICARBAZONE AND 2-HETANONETHIOSEMICABAZONE
Complexes of Nickel(II) with 2-heptanonesemicarbazone (hsc) and 2-heptanonethiosemicabazone (htc) have been synthesized and characterized by elemental analysis, molar conductance measurements, magnetic moments, mass, IR and electronic/spectral studies. Synthesized complexes were found to have a general composition of Ni(L)2X2 (where X=Cl-, 1/2SO42-, NO3-, ClO4-, NCS-, CH3COO- and L=hsc or htc). Mo...
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STUDY OF CLINICAL AND HISTOPATHOLOGICAL PATTERN, SEVERITY, CAUSALITY AND COST ANALYSIS IN HOSPITALISED PATIENTS WITH CUTANEOUS ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL
Objectives: To assess clinical and histopathological patterns, causative drugs, causality, severity and cost of treating cutaneous adverse drug reactions (CADRs) among patients admitted in tertiary care teaching hospital. Methods: In a prospective hospital-based study over a period of one year (June 2015- June 2016), CADRs of patients admitted to the dermatology department were recorded. The data ...
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1665
AN INSIGHT INTO NEUROPATHIC PAIN: A SYSTEMIC AND UP-TO-DATE REVIEW
Neuropathic pain is a chronic illness that originates when abnormal functioning in the nervous system is observed or if the nervous system, including peripheral nerves, spinal cords, and brain, is damaged or not working properly, and originating pain. Therefore, it can be said that neuropathic pain is a chronic illness that directly impacts a large number of patients, society, and healthcare syste...
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1625
SIMULTANEOUS ESTIMATION OF ESOMEPRAZOLE AND NAPROXEN IN BULK AS WELL AS IN PHARMACEUTICAL FORMULATIONS BY USING RP-HPLC
Esomeprazole is used to treat gastro esophageal reflux disease. Naproxen is a Non-steroidal anti-inflammatory drug (NSAID) used in the treatment of pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. A simple, precise, cost effective RP-HPLC method was developed and validated for the determination of both Esomepraz...
3992
1980
ANTIOXIDANT STUDIES, ERYTHROCYTE MEMBRANE STABILIZATION AND THROMBOLYTIC POTENTIAL OF DIALLYL DISULPHIDE
Diallyl Disulphide is an essential component of garlic which has numerous medicinal applications. Thus it was evaluated for its free radical scavenging potential. The compound was assayed for its ability to stabilize the erythrocyte membrane by osmotic fragility test and heat induced hemolysis assay. The thrombolytic potential was evaluated by the ability of the compound to dissolve the clot forme...
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1543
A SENSITIVE RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF DIETHYLCARBAMAZINE AND LEVO-CETIRIZINE IN BULK AND PHARMACEUTICAL DOSAGE FORM
A simple, sensitive and reproducible method was developed and validated for the simultaneous estimation of Diethylcarbamazine and Levocetirizine in its tablet formulation by reverse phase high performance liquid chromatography using Waters1515 HPLC with Diethylcarbamazine and Levocetirizine simultaneously. HPLC-PDA detector at the λmax of 253nm, using Hypersil-BDS C18 (250×4.6 mm. 5 μ) column. ...
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1925
RP-UPLC METHOD FOR COMBINATIONAL ASSAY OF LORNOXICAM AND PARACETAMOL IN COMBINED TABLET DOSAGE FORM
A simple, precise and stability-indicating ultra-performance liquid chromatography (UPLC) method for simultaneous determination of Paracetamol (PCM) and Lornoxicam (LOR) in tablet formulations has been developed and validated. The UPLC separation was achieved on a Waters Acquity UPLC BEH shield RPC18 (2.1x50mm, 1.7µm) column using acetonitrile:30mM Ammonium acetate (40:50, v/v) as mobile phase at...
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