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MURRAYA KOENIGII MEDIATED SILVER NANOPARTICLE SYNTHESIS AND ITS ACTIVITY AGAINST ENTERIC PATHOGENS
Objective: The objective of this research was a synthesis of silver nanoparticles from Murraya koenigii leaves in which the particles were characterized by various techniques and to evaluate the potential antibacterial activity of synthesized nanoparticles against various human pathogens. Methods: Murraya koenigii aqueous extract of leaves were prepared by the Soxhlet method, and the bioactive com...
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2637
DEVELOPMENT OF REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD AND ITS VALIDATION FOR ESTIMATION OF FORMOTEROL FUMARATE ROTA CAPS
A simple, rapid and reproducible HPLC method was developed and validated for the estimation of Formoterol Fumarate Rotacaps. Symmetry C8 (4.6×150mm, 5 µ) column, in isocratic mode with mobile phase containing Ammonium Acetate Buffer pH 5.0 and Acetonitrile (80:20) was used. The flow rate was 1.0 ml/min and the analyte was monitored at 254 nm. The retention time for Formoterol was about 4.6 mins....
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1632
PREPARATION AND EVALUATION OF HPMC-ALGINATE MUCOADHESIVE MICROCAPSULES OF DICLOFENAC FOR CONTROLLED RELEASE
A new, novel promising technology for obtaining controlled release and enhancing the bioavailability is a combination of mucoadhesion principle and microencapsulation to result in mucoadhesive microcapsules. Mucoadhesive microcapsules consist of either entirely of a mucoadhesive polymer or having an outer coating enclosing the drug particles. They facilitate an intimate and prolonged contact with ...
3999
1567
COMPARATIVE ANTIBACTERIAL STUDY OF DIFFERENT EXTRACT OF CLAVERIA ROSEA FRIES AGAINST GRAM NEGATIVE AND GRAM POSITIVE PATHOGENS
Objective: To compare the antibacterial activity of different solvent extract of Clavaria rosea. Method: Different solvent extract of Claveria rosea was prepared. Standard cultures of Escherichia coli (MTCC-1698), Klebsiella pneumoniae (MTCC-7028), Pseudomonas aeuroginosa (MTCC-1934), Salmonella typhi (MTCC-733), Xanthomonas campestris (MTCC-2286), Pseudomonas syringae (MTCC-1604) and Agrobacte...
3998
1376
AN INSIGHT INTO NEUROPATHIC PAIN: A SYSTEMIC AND UP-TO-DATE REVIEW
Neuropathic pain is a chronic illness that originates when abnormal functioning in the nervous system is observed or if the nervous system, including peripheral nerves, spinal cords, and brain, is damaged or not working properly, and originating pain. Therefore, it can be said that neuropathic pain is a chronic illness that directly impacts a large number of patients, society, and healthcare syste...
3998
1625
SYNTHESIS AND SPECTRAL STUDIES OF Ni(II) COMPLEXES WITH 2-HEPTANONESEMICARBAZONE AND 2-HETANONETHIOSEMICABAZONE
Complexes of Nickel(II) with 2-heptanonesemicarbazone (hsc) and 2-heptanonethiosemicabazone (htc) have been synthesized and characterized by elemental analysis, molar conductance measurements, magnetic moments, mass, IR and electronic/spectral studies. Synthesized complexes were found to have a general composition of Ni(L)2X2 (where X=Cl-, 1/2SO42-, NO3-, ClO4-, NCS-, CH3COO- and L=hsc or htc). Mo...
3997
1701
STUDY OF CLINICAL AND HISTOPATHOLOGICAL PATTERN, SEVERITY, CAUSALITY AND COST ANALYSIS IN HOSPITALISED PATIENTS WITH CUTANEOUS ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL
Objectives: To assess clinical and histopathological patterns, causative drugs, causality, severity and cost of treating cutaneous adverse drug reactions (CADRs) among patients admitted in tertiary care teaching hospital. Methods: In a prospective hospital-based study over a period of one year (June 2015- June 2016), CADRs of patients admitted to the dermatology department were recorded. The data ...
3997
1668
ANTIOXIDANT STUDIES, ERYTHROCYTE MEMBRANE STABILIZATION AND THROMBOLYTIC POTENTIAL OF DIALLYL DISULPHIDE
Diallyl Disulphide is an essential component of garlic which has numerous medicinal applications. Thus it was evaluated for its free radical scavenging potential. The compound was assayed for its ability to stabilize the erythrocyte membrane by osmotic fragility test and heat induced hemolysis assay. The thrombolytic potential was evaluated by the ability of the compound to dissolve the clot forme...
3996
1543
EMERGING MECHANISMS AND POTENTIAL ANTIDEPRESSANT ACTION OF MEDICINAL PLANTS
Depression is a common heterogeneous, debilitating and life-threatening mood disorder affecting different segments of the community. Several chemical and synthetic medicines as standard are being employed to treat depression and may lead to complete recovery in only 50% of clinically depressed patients but causes many adverse effects. Thus, scientists are increasing their interest in research towa...
3996
2668
SIMULTANEOUS ESTIMATION OF ESOMEPRAZOLE AND NAPROXEN IN BULK AS WELL AS IN PHARMACEUTICAL FORMULATIONS BY USING RP-HPLC
Esomeprazole is used to treat gastro esophageal reflux disease. Naproxen is a Non-steroidal anti-inflammatory drug (NSAID) used in the treatment of pain or inflammation caused by conditions such as arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps. A simple, precise, cost effective RP-HPLC method was developed and validated for the determination of both Esomepraz...
3995
1984