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DESIGN AND IN-VIVO EVALUATION OF TOPICALLY APPLIED CHLORPHENIRAMINE MALEATE GELS
This study was aimed at formulating topically applied Chlorpheniramine maleate gel (CPM gel). Combined effects of propylene glycol and polyethylene glycol as permeation enhancers were investigated using response surface methodology. The formulated gels were characterized for various formulation attributes including viscosity, homogeneity, pH, spreadability and accelerated stability studies (40 ± ...
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A COMPREHENSIVE REVIEW ON THE USEFULNESS OF TELEHEALTH INTERVENTION FOR CHILDREN WITH DISABILITY WITH SPECIAL REFERENCE TO SAUDI ARABIA
Background: Healthcare requirements have changed gradually from the primitive ages to this modern era. Information and communication technology has opened innovative techniques like home healthcare for patients through telehealth use. Aims: 1. To find out the usefulness and effectiveness of telehealth intervention on the daily living activities amongst children with disability in Saudi Arabia. 2. ...
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ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF AQUA FORM OF CAESALPINIA BONDUCELLA SEED IN RATS
The objective of this study is to evaluate the analgesic and anti-inflammatory activities of the Caesalpinia bonducella in animals. The analgesic action was evaluated in rats using the acetic acid-induced writhing test and the hot-plate test. The anti-inflammatory activity was estimated using carrageenan-induced paw edema in rats. Caesalpinia bonducella strikingly and dose-dependently suppressed c...
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PHYTOCHEMICAL SCREENING AND GUT MOTILITY ACTIVITY OF ETHANOLIC EXTRACT OF WHOLE PLANT OF SCUTIA MYRTINA KURZ.
Phytochemical and Gut motility activity of Ethanolic Extract of whole plant of Scutia Myrtina Kurz collected from Kolli Hills, Tamil Nadu was studied. Phytochemical studies revealed the presence of Alkaloids, Glycosides (Anthraquinone), Flavonoids and Tannins. For Gut Motility activity Extracts in concentration of 200mg/Kg and 400mg/Kg were studied in three animal models in comparison to Caster Oi...
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PREVALENCE AND SUSCEPTIBILITY PATTERN OF E. COLI IN LOW BIRTH WEIGHT NEONATES OF EARLY ONSET SEPSIS
Neonatal sepsis is one of the commonest cause of neonatal mortality in the developing world which can be classified into early onset sepsis (EOS) which occurs in the first 7 days of life and late onset sepsis (LOS) which occurs ≥7 days of life. E. coli has been reported to be one of the significant and most common nosocomial pathogen which may cause septicemia, pneumonia and meningitis in the ne...
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EFFECTIVENESS OF ANTIBIOTICS IN INCREASING THE FUNCTIONAL CAPACITY AND REDUCING THE ECONOMIC BURDEN IN FEMALE URINARY TRACT INFECTION PATIENTS
Background: Urinary tract infection is a common medical problem for women throughout their lifetime. Recurrence after urinary tract infection (rUTI) is common in adult women. The majority of recurrences are believed to be reinfection from extra urinary sources such as rectum or vagina. The treatment of recurrent urinary tract infection also inflicts an economic burden on the patient’s life. Henc...
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ANTIMICROBIAL ACTIVITY OF EUGENOL AGAINST HUMAN PATHOGENIC BACTERIA BY MINIMAL INHIBITORY CONCENTRATION, MINIMAL BACTERICIDAL CONCENTRATION AND DISC-DIFFUSION METHODS
Essential oils from plants have been reported to have antibacterial activity. Essential oil is a mixture of many chemicals, and one or more chemicals in essential oil may have antibacterial activity. In our laboratory, essential oil from the leaves of Ocimum sanctum L. was found to have antibacterial activity against 18 human bacteria. GC-MS analysis of the Ocimum sanctum essential oil revealed th...
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A SURVEY ON LINE OF MANAGEMENT OF HYPERTENSION BY PRIMARY HEALTH CARE PHYSICIANS IN PUDUDCHERRY
Hypertension is one of the most important public health problems globally. If the blood pressure is effectively controlled, many of the disastrous complications of hypertension such as myocardial infarction, stroke, kidney failure, heart failure, and death can be prevented or delayed. Patients usually attend the family physicians first for any illness they are suffering, including hypertension. He...
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COMPARATIVE EFFECTIVENESS OF SIMULATION BASED TEACHING VERSUS CONVENTIONAL TEACHING FOR UNDERGRADUATE STUDENTS OF SECOND PROFESSIONAL M.B.B.S IN EXPERIMENTAL PHARMACOLOGY
Aims: To evaluate and analyze effectiveness of animal simulation based teaching in pharmacology in comparison to conventional methods to undergraduate medical students. Methods: An interventional and comparative study was conducted among second professional MBBS students. All students were divided into two groups A and B. Four demonstrations of experimental pharmacology were demonstrated by conven...
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ANTIBACTERIAL AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACT OF SPILANTHES CALVA (DC) LEAVES
Methanol extract of leaves of Spilanthes calva (DC) was examined for their antimicrobial and cytotoxic properties. To determine antibacterial activities, the extract was tested against four gram-positive and six gram-negative bacteria at three concentrations (500, 800, 1000 µg disc-1) through disc diffusion method. The extract showed moderate antibacterial actions and that was increased by increa...
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