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STUDY OF ANTITUSSIVE POTENTIAL OF GLYCYRRHIZA GLABRA AND ADHATODA VASICA USING A COUGH MODEL INDUCED BY SULPHUR DIOXIDE GAS IN MICE
Cough is the most common symptom of respiratory diseases. When cough becomes serious, opioids are effective, but they have side effects like sedation, constipation. Therefore, there is a need to have effective antitussive agent which do not have respiratory depressant activity. The present study was carried out to evaluate antitussive activity of Glycyrrhiza glabra and Adhatoda vasica using a coug...
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ENVIRONMENTAL FRIENDLY WETCHEMICAL SYNTHESIS AND CHARACTERIZATION OF TRANSITION METAL DOPED PARTICLE
Transition metal doped zinc oxide particles were synthesized in aqueous phase adopting a low cost, easy and environmental friendly route. The precursors used in the preparation of Co doped ZnO (Zn0.95Co0.05O) and ZnO (Zn0.9oCo0.1O) by wet process are zinc acetate dehydrates cobalt chloride, sodium hydroxide, di-ethylene glycol and double distilled water. The doped ZnO particles were characterized ...
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CARBON NANOTUBES AND ITS APPLICATIONS
Carbon nanotubes are the technology that imagination by many scientists in the different country. There are small strengths, dimensions, and the remarkable physical properties of the carbon nanotubes that structures make a very unique material with a whole range of various applications. There are discussing some of the important application of materials science use in carbon nanotubes. There are...
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COMPARATIVE QUALITY EVALUATION OF SOME METRONIDAZOLE TABLETS AND METRONIDAZOLE BENZOATE ORAL SUSPENSIONS AVAILABLE IN RETAIL OUTLETS OF ADDIS ABABA, ETHIOPIA
In this study, five different products of each metronidazole tablets and benzoate salt oral suspensions were purchased from the different retail outlets in the local market of Addis Ababa and analyzed using official methods (Pharmacopoeial methods of USP/BP/IP) by employing HPLC for the tablet dosage forms and non-aqueous titration with potentiometric end point for the suspensions. The assay resul...
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SOLID DISPERSION: OVERVIEW OF THE TECHNOLOGY
Up to 40% of new chemical entities (NCEs) discovered today by the pharmaceutical industry through combinatorial chemistry and high through put screening are highly lipophilic or poorly water soluble compounds, so the number of such compounds has dramatically increased and the solubility behaviour of these drugs has become one of the most challenging aspects in formulation development. So amongst t...
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RECENT TREND IN TRADITIONAL MEDICINE DOSAGE FORM AND PRESENT STATUS OF UNANI AND AYURVEDIC MEDICINE
Traditional medicine is finding more significance and application today, particularly when we are facing difficulty in the management of numerous medical conditions. More effective and palatable drug dosage forms are needed in the modern era. The recent trend in traditional medicine dosage forms is to enhance the solubility, bioavailability, pharmacological activity, stability, reduce the toxicity...
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¬POST-STROKE DEPRESSION: PATHOLOGLOGY, DIAGNOSIS AND TREATMENT STRATEGY
Post stroke depression is most commonly faced psychiatric challenge, causing severe disability. Post stroke depression (PSD) occurs in nearly one-third patients either during acute/chronic stroke period. It’s often under-diagnosed. A good diagnosis must be done within one month after stroke, based on self-reporting tools, followed by observer-rated interview. Mechanism is multifactorial, present...
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CHITOSAN: A NOVEL EXCIPIENT IN PHARMACEUTICAL FORMULATION: A REVIEW
Chitosan is a cationic natural polysaccharide which is derived from the chitin of crustaceans, with crabs and shrimp-shell wastes as its principal source. Its properties includes extent of deacetylation and the average molecular weight of polymer as well as low toxicity and good bioavailability make it a novel excipient in pharmaceutical formulation as a relatively new development. Together with c...
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MEDICINAL PROPERTIES OF RICINUS COMMUNIS: A REVIEW
The medicinal plant Ricinus communis is one of the effective plants which offer a solution to several kinds of diseases. Owing to this, the present research aims to review the medicinal properties of one of such common herbal plants, Ricinus communis, its possible role as herbal medicine, and assessment for pharma-covigilance. Related research articles were collected from Google Scholar, Pub Med, ...
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ANXIETY DISORDERS AND HERBAL MEDICINES
Anxiety is a common and normal phenomenon, involving multiple brain regions, including amygdala, locus ceruleus and frontal cortex. Moreover, multiple brain transmitters regulate the presence and severity of anxiety; these include classical transmitters such as gamma amino butyric acid, serotonin, and dopamine, as well as neuropeptides that include corticotrophin releasing hormone, substance P, ne...
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