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SUBACUTE ANTIDIABETIC PROPERTIES OF AGERATUM CONYZOIDES LEAVES IN DIABETIC RATS
This study investigated the antidiabetic activity of the aqueous extract of the leaves of Ageratum conyzoides. Streptozotocin induced hyperglycemia male adult albino rats were used to study the antidiabetic effect of Ageratum conyzoides aqueous extract (at doses of 100, 200 and 300 mg/kg respectively). The diabetic rats were housed in metabolic cages, for the whole period of the experiment. Body w...
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MEDICINAL PLANTS WITH ANTI-ULCER AND HEPATOPROTECTIVE ACTIVITY: A REVIEW
Nature gives numbers of drugs and possibly has all solutions for human diseases. Till date, nature provides a large number of clinically useful drugs. Ulcer and liver diseases are major increasing health problems. Now a day number of drugs are used for the treatment of peptic ulcer and hepatic diseases, but these drugs have various types of side effect such as incidences of relapse, and drug inter...
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PAEDERIA FOETIDA LINN: PHYTOCHEMISTRY, PHARMACOLOGICAL AND TRADITIONAL USES
Paederia foetida (Skunk vine) an indigenous plant belongs to family Rubiaceae. The plant is having a broad spectrum of use as in treatment of ailments like hepatic disorders, rheumatoid arthritis, constipation, diabetes, coughs, asthma, itches, wounds, stomachache, diarrhoea, dysentery, pain, typhoid, pneumonia, toothache, cancer, flatulency, body ache, and bone fractures etc. Literature data reve...
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RECENT DEVELOPMENT AND ACHIEVEMENTS IN SOLUBILITY AND DISSOLUTION ENHANCEMENT OF ITRACONAZOLE: A REVIEW
A drug should be available in accessible in disintegrated state before producing its therapeutic effect however; in current market more than 40%, drugs are poorly soluble in water. In view of their low aqueous solubility, those new chemical entities fail to reach market in spite of revealing potential pharmacodynamics activities. Poorly aqueous soluble drugs are connected with moderate drug absor...
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2098
3D-QSAR AND CONTOUR MAP ANALYSIS OF TARIQUIDAR ANALOGUES AS MULTIDRUG RESISTANCE PROTEIN-1 (MRP1) INHIBITORS
One of the major obstacles to the successful chemotherapy towards several cancers is multidrug resistance of human cancer cells to anti-cancer drugs. An important contributor to multidrug resistance is the human multidrug resistance protein-1 transporter (MRP1), which is an efflux pump of the ABC (ATP binding cassette) superfamily. Thus, highly efficacious, third generation MRP1 inhibitors, like t...
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ESTIMATION OF MOISTURE AND CRUDE PROTEIN CONTENT OF LOCALLY AVAILABLE RAW MATERIALS FOR POULTRY FEED
There are some locally available domestic material in our country that can be used in poultry feed. The uses of local material will decrease the feed cost as well as ensure the availability of raw materials. In this investigation we have selected twelve locally available domestic materials that are low cost and nutritious for poultry health. These raw materials play an important role on poultry he...
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AN UPDATED PHARMACOLOGICAL ACTIVITY OF COCCINIA INDICA (WIGHT & ARN.)
Traditional system of medicine consists of large number of plants with various medicinal and pharmacological importances and hence represents a priceless tank of new bioactive molecules. Coccinia indica belongs to the family Cucurbitaceae. It is a rapidly growing, perennial climber or trailing vine. Traditionally different parts of this plant namely the roots, leaves and fruits are used in folklor...
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APPROACHES AND SIGNIFICANCE OF TRANSDERMAL DRUG DELIVERY SYSTEMS: A REVIEW
Transdermal Drug Delivery System (TDDS) is the most innovative and Novel drug delivery systems by penetrating through the skin by increasing the scope of molecules that can be delivered. TDDS that traditionally uses a patch containing loaded drug substances pressed on to the skin is convenient, painless and non-invasive, to avoid gastro intestinal (GI) tract toxicity (peptic ulcer disease). Tran...
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1901
A REVIEW ON THE SUGAR ALTERNATES
Background: Due to the rise of diabetes as the primary health issue nowadays, there is a need for a sweetener, which apart from fulfilling the role of a sweetener, also complies with the normal body metabolism. Objectives: To review the literature available on the different sugar alternates present globally. Methods: A literature search has been done on the various substitutes of sugar present, be...
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1914
PHARMACOLOGICAL IMPORTANCE OF CITRUS FRUITS
This paper reviews the pharmacological importance of citrus fruits. Citrus fruits are used for various pharmacological importance. According to literature the citrus fruit possess anti-cancer, antimicrobial, antioxidant, antiulcer, anti-inflammatory, and hypolipidemic and hepatoprotective properties....
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