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COMPARATIVE QUALITY EVALUATION OF PARACETAMOL TABLET MARKETED IN SOMALI REGION OF ETHIOPIA.
The safety and efficacy of a pharmaceutical dosage form can be guaranteed when its quality is reliable. The efficacy of pharmaceutical dosage forms generally depends on their formulation properties, and manufacturing methods, hence it is likely that the quality of dosage form may vary. The aim was to evaluate the quality of paracetamol tablet marketed in Somali region of Ethiopia. The study was ex...
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2169
A REVIEW ON TOMATO LYCOPENE
Lycopene, a non-provitamin a carotenoid, found in tomatoes, processed tomato products and other fruits, due to which red to pink coloration is observed. Among all the dietary carotenoids, lycopene is one of the most potent naturally and abundantly occurring antioxidant. Lycopene has unique structural features and chemical features which contribute to specific biological properties and pharmacologi...
8187
1904
SOLID LIPID NANOPARTICLES; A REVIEW
Solid lipid nanoparticles (SLN) are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery and research. Due to their unique size dependent properties, lipid nanoparticles offer possibility to develop new therapeutics. The ability to incorporate drugs into nanocarriers offers a new prototype in drug delivery that could use for drug t...
8166
1997
FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS BY USING NATURAL POLYMER
The study was aimed at developing mucoadhesive buccal tablet containing Carvedilol. The effect of two independent variables, Casein (X1) and hydroxypropylmethyl cellulose (HPMC K4M) (X2) at three different levels (-1, 0, +1) on dependent variable including hardness (Y1), cumulative percentage drug release at 6 h (Y2) and 12 h (Y3) using 32 full factorial design. FTIR and DSC results showed no ...
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1887
BIOSIMILAR: AN OVERVIEW
Biosimilars are defined as officially approved new version of innovator bio-therapeutic products for which the patent has expired. Biosimilars the ‘generic’ versions of biopharmaceuticals, continue to enter Indian pharmaceutical market, to treat a variety of diseases. Biosimilars available in India include monoclonal antibodies for treating various malignant and immunological disorders, growth...
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2551
FORMULATION AND EVALUATION OF NANOSUSPENSION TO IMPROVE SOLUBILITY AND DISSOLUTION OF DIACEREIN
Diacerein is an Osteoarthritic drug that exhibited suboptimal oral bioavailability upon oral administration of conventional dosage form. Nanosuspension gaining more attention for improving oral bioavailability of such drugs. This study was aimed to enhance the solubility and dissolution of diacerein by preparing Nanosuspension. Diacerein Nanosuspension was prepared using combination of High Speed ...
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2279
FLUORIDE AND BRAIN: A REVIEW
The mammalian central nervous system is composed of the brain and spinal cord. The brain is protected by the blood-brain barrier (BBB) that allows selective traffic of substances into the brain. Fluoride is a highly toxic and reactive element. We get exposed to fluoride due to its common use in toothpaste, dental gels, non-stick pans, razor blades, etc. Fluoride also enters our food chain through ...
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1532
BIOACTIVE COMPOUNDS FROM MICROALGAE AND CYANOBACTERIA: UTILITY AND APPLICATIONS
Microalgae and Cyanobacteria (blue-green algae) are photosynthetic prokaryotes used as food by humans. They have gained a lot of attention in recent years because of their potential applications in biotechnology. They have also been recognized as an excellent source of vitamins and proteins and as such are found in health food stores throughout the world. They are reported to be a source of fine c...
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3028
PREVALENCE OF HYPOTHYROIDISM AND ITS CO-MORBIDITIES IN RELATION TO THE CAUSES AND RISK FACTORS IN PATIENTS UNDERGOING LEVOTHYROXINE THERAPY
Hypothyroidism is a metabolic disorder, which results in slower rate of metabolism leading to life threatening medical conditions like diabetes and other complications. This study aims to analyze the prevalence of hypothyroidism and its co-morbidities in relation to the causes and risk factors in patients undergoing levothyroxine therapy and to know the adherence level of prescribers to the Thyroi...
8128
1395
NOVEL COLON SPECIFIC DRUG DELIVERY SYSTEM: A REVIEW
Now a days, various routes of administration have been explored for the effective delivery of the drug to the target site. The oral route is considered to be most convenient for the administration of drugs to patients. But it has a serious drawback in conditions where localized delivery of the drug in the colon is required. Colon target aimed mainly because of less enzymatic activity, longer tra...
8126
2020