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HYDROALCOHOLIC EXTRACTION OF MANGIFERA INDICA (LEAVES) BY SOXHLETION
The genus Mangifera indica belongs to the family Anacardiaceae and comprises of 40 species distributed in tropical and sub-tropical parts of South East Asia, Africa and Latin America The resin is useful in cutaneous disease .the juice of kernel is snuffed to stop nasal bleeding. A decoction of the leaves with a little honey added is given in aphonia, the loss of voice. Mid ribs of the leaves calci...
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ANTIMICROBIAL ACTIVITY OF ALOE VERA GEL AND HONEY AGAINST BACTERIA ISOLATES FROM WOUND ASPIRATES
Wounds may harbour diverse microorganisms, especially bacteria that are resistant to many conventional antibiotics. The aim of this study is therefore to evaluate the antibiotic activities of Aloe vera gel and honey against bacteria isolates from wounds. A cross sectional study of wound aspirates from a health care center was carried out to evaluate the antibacterial activities of Aloe vera and ho...
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MOUTH DISSOLVING TABLETS: AN OVERVIEW
The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. One such problem can be solved in the novel drug delivery system by formulating “mouth dissolving tablets” (MDTs) which disintegrates or dissolves rapidly without water with in few seconds...
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STABLE FORMULATION OF ACECLOFENAC AND THIOCOLCHICOSIDE TABLETS
The present study relates to the stable fixed dose combination comprising of Aceclofenac as a glycolic acid ester of Diclofenac is having analgesic and anti-inflammatory action and Thiocolchicoside, as a glycosulfurated analogue of colchicine which is well known centrally acting muscle relaxant in unit dosage form and to the preparation method thereof. Aceclofenac is very susceptible to decomposit...
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IONTOPHORESIS: AN APPROACH TO DRUG DELIVERY ENHANCEMENT
The skin has been used as a medium for systemic delivery of therapeutic agents. The resistance provided by the stratum corneum is the major barrier in delivering of the agents through skin. Due to this the number of drug molecules used under this category is limited. Iontophoresis is an efficient technique for physically enhancing conveyance of molecules across skin for local and systemic effects....
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THERAPEUTIC POTENTIAL OF HYPERICUM PERFORATUM: A REVIEW
The irreversible effects of modern therapies and increasing drug resistance have augmented our reliance on medicinal plants for herbal remedy against the deadly and infectious diseases. Hypericum perforatum or St. John’s wort (SJW) family Clusiaceae has been used to treat depression, mental disorders, wounds, peptic ulcers, malaria, gout and arthritis. Various compounds of the plant are known as...
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EFFECT OF RELATIVE HUMIDITY ON ACETAMINOPHEN TABLET PROPERTIES PREPARED BY DIFFERENT TECHNIQUES USING POLYVINYLPYRROLIDINE DERIVATIVES AS BINDER
Amount of moisture content present in solid dosage forms plays a major role in influencing the physicochemical properties of tablets such as dissolution rate, disintegration time, hardness, etc. The aim of the current study was to investigate the effect of relative humidity (RH) exposure on various properties of acetaminophen tablets manufactured by direct compression and wet granulation methods. ...
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APPROACHES AND SIGNIFICANCE OF TRANSDERMAL DRUG DELIVERY SYSTEMS: A REVIEW
Transdermal Drug Delivery System (TDDS) is the most innovative and Novel drug delivery systems by penetrating through the skin by increasing the scope of molecules that can be delivered. TDDS that traditionally uses a patch containing loaded drug substances pressed on to the skin is convenient, painless and non-invasive, to avoid gastro intestinal (GI) tract toxicity (peptic ulcer disease). Tran...
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AN UPDATED PHARMACOLOGICAL ACTIVITY OF COCCINIA INDICA (WIGHT & ARN.)
Traditional system of medicine consists of large number of plants with various medicinal and pharmacological importances and hence represents a priceless tank of new bioactive molecules. Coccinia indica belongs to the family Cucurbitaceae. It is a rapidly growing, perennial climber or trailing vine. Traditionally different parts of this plant namely the roots, leaves and fruits are used in folklor...
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EFFECT OF DIFFERENT CARBON AND NITROGEN SOURCES ON α- AMYLASE PRODUCTION FROM BACILLUS AMYLOLIQUEFACIENS
Amylases are among the most important enzymes in present-day biotechnology. The effects of various carbon and nitrogen sources on α-amylase production by submerged fermentation (smF) from Bacillus amyloliquefaciens was investigated. The study revealed that the levels of the α- amylase production varied greatly with the type and concentration of carbon and nitrogen sources used. The highest α-am...
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