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ANTIMICROBIAL ACTIVITY OF UPAVISHA AND ITS CLINICAL CORRELATION WITH CONTEMPORARY SCIENCE: A REVIEW
In Ayurveda, there are less toxic herbal drugs known as upavisha. Upavisha are mostly use in various diseases with many therapeutically preparations. As per Ayurveda, Upavisha is group of less toxic drug. These drugs are either not having all ten gunas or they have less potent gunas. The properties of these drugs are to cure acute and chronic disease. These groups also have antimicrobial/ anti- in...
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2657
CARDIAC ARRYTHMIASIS AND ITS DETAILED PATHOPHYSIOLOGY – A REVIEW
Amid the previous couple of years, the improvement of powerful, experimental innovations for treatment of cardiovascular arrhythmias has surpassed the pace at which itemized information of the basic science has aggregated. Cardiac arrhythmia is a group of conditions in which the heartbeat is irregular, either too fast, or too slow and is characterized by abnormal electrical conduction in the heart...
7227
2097
FORMULATION AND CHARACTERIZATION OF NIMODIPINE NANOEMULSION AS AMPOULE FOR ORAL ROUTE
The aim of this study was to develop oil in water nanoemulsion of nimodipine intended for oral use. Nimodipine is a calcium channel blocker that has poor oral bioavailability (3-30%) due to its low solubility and first- pass metabolism. So, nanoemulsion of nimodipine increase its solubility and enhance its oral bioavailability. Pseudo -ternary phase diagrams were made by using aqueous titration me...
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2324
SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE PROTEASE INHIBITOR
There are more than 40% of drugs which are poorly soluble and 90% of the drugs from the pipeline are from BCS class II and IV. Application of techniques like computers, robotics, high-throughput screening, combinatorial chemistry have resulted in database of huge drug-like molecules which are generally derived solely based on the affinity of the molecule with the target physiological bodies viz....
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2388
VERIFICATION STRATEGIES FOR ESTABLISHING RELIABILITY AND VALIDITY IN PHARMACEUTICAL MANUFACTURING PROCESS- AN ENROUTE TO REGULATORY COMPLIANCE
The Process validation involves a series of activities over the lifecycle of the product and process. The FDA guidance described three stages of process validation which includes Process Design, Process Qualification, and Continued Process Verification (CPV). The CPV stage is a never ending approach that continues throughout the entire commercial lifecycle of the product. CPV is dependent on compl...
7217
2758
PRELIMINARY PHYTOCHEMICAL SCREENING AND PHARMACOLOGICAL EVALUATION OF THE LEAVES OF BUTEA MONOSPERMA
Various parts of the plant Butea monosperma have been used traditionally for many of the diseases like anti-inflammatory, antimicrobial, anthelmintic, antidiabetic, diuretic, analgesic, antitumor, anticancer, astringent activities. Among the various parts of the Butea monosperma first choice is selection of leaves in our current research work because only scanty work has been done on leaves. So it...
7204
1932
PHARMACOLOGICAL SIGNIFICANCE OF MEDICINAL HERB ECLIPTA ALBA L. – A REVIEW
Though conventional medicines are slow in action, they represent safety in contrast to the synthetics that are regarded as somewhat unsafe to human and environment. The uses of many traditional herbs in the treatment of many diseases, which are usually free from side effects, are economical and also easily accessible to humans. Plants have formed the basis of sophisticated traditional medicine sys...
7202
1484
STANDARDIZATION OF ‘BHUNIMBADI CHURNA’ – AN AYURVEDIC POLYHERBAL FORMULATION
Standardization of herbal formulation is essential in order to assess the quality of drugs for therapeutic value. The present work is an attempt to standardize ‘Bhunimbadi Churna’, an Ayurvedic polyherbal formulation, used in fever and diabetics etc. The various parameters performed included organoleptic characteristics, physico-chemical parameter, physical characteristics of Churna, prelimina...
7190
2007
CURCUMIN: TRANSFORMING THE SPICE TO A WONDER DRUG
Turmeric is a spice obtained from the dried rhizomes of Curcuma longa, family Zingiberaceae. It has been extensively used in traditional Indian (Ayurveda) and Chinese medicine for various ailments such as anti-inflammatory, blood purifier and even as a cosmetic. Curcumin, the chief constituent in turmeric has been isolated centuries ago, has been found to have a wide range of pharmacological actio...
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2602
DESIGN, FORMULATION AND EVALUATION OF BITTER LEAF TABLETS
Vernonia amygdalina, commonly called bitter leaf, is a perennial shrub that belongs to the family Asteraceae and grows throughout tropical Africa. Traditional medicine practitioners use the plant as in treatment of several disease conditions especially diabetes mellitus. In this research, the feasibility of tableting Vernonia amygdalina leaf was examined using three binders. Tableting of the leaf ...
7185
1852