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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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8.

REVIEW ON MICROSPONGE LEADING MICROPOROUS PARTICULATE TECHNOLOGY WITH CONTROLLED RELEASE, IMPROVE STABILITY TO PROVIDE OPTIMUM SKIN DISORDERS MANAGEMENT ENVIRONMENT FOR THERAPEUTIC APPLICATION

Although serious systemic and cutaneous side effects need a novel delivery system that provides prolonged and controlled drug release, minimum systemic drug absorption with reduced side effects. Microsponge, a drug delivery system, possesses the versatility to load a wide range of active ingredients to facilitate the controlled release of active ingredients to reduce systemic exposure and to reduc...

N. Tomar, N. Pawar * and K. Bahmani

Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, Bhiwani, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5360-75

5360-5375

2642

2184

2.

NANOTHERAPEUTIC APPROACHES, PHYTOCHEMISTRY AND PHARMACOLOGICAL PROSPECTS OF PLANT MUSSAENDA FRONDOSA LINN: A HOLISTIC INVESTIGATION

Medicinal plants provide numerous benefits to human health. Mussaenda frondosa Linn belongs to the Rubiaceae family, which has 500 genera and 5300 medicinal plant species. Mussaenda is a flowering plant genus with many beautiful species. Ayurveda, an ancient Indian healing system, describes many herbs, oils, and minerals. People have known about plants' medicinal value since prehistoric times. Mus...

Aseem Setia, Sanjay Nagdev, Mrinal Sharma, Shashi Alok, Sandip Tiwari, Megha Verma, Pradeep Golani, Devendra Singh Lodhi and Sankha Bhattacharya *

School of Pharmacy & Technology Management Shirpur, SVKM'S NMIMS Deemed-to-be University, Shirpur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(7).2562-74

2562-2574

2641

3201

2.

CANCER-ASSOCIATED THROMBOSIS: AN OVERVIEW OF THROMBOSIS MECHANISMS AND ITS RISK FACTORS IN CANCER

Thrombosis is one of the major causes of death and disability worldwide. Cancer patients are commonly thrombophilia or prothrombotic since they have abnormalities in all three factors of Virchow's triad, which lead to thromboembolism. Venous thrombosis (VT) is a chronic disorder that has the potential to be fatal and cause considerable complications. Venous thromboembolism (VTE) may potentially be...

Prashu Yadav, Ashok Kumar Gupta, Rakesh K. Sindhu, Shashi Alok and Vinod Kumar Gupta *

Rapture Biotech International Pvt. Ltd 1, D-201, Sector-10, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.14(9).4225-36

4225-4236

2640

1256

48.

SOLUBILITY ENHANCEMENT AND OPTIMIZATION OF VARIOUS VARIABLES OF FAST DISINTEGRATING TABLETS OF LERCANIDIPINE HYDROCHLORIDE USING CENTRAL COMPOSITE DESIGN

The oral route of drug administration is the most common and preferred method of delivery due to convenience and ease of ingestion, but it is problematic if the drug is poorly soluble. Sufficient drug absorption, reproducible bioavailability and pharmacokinetic profile of orally administered drug substances are highly dependent on the solubility of that compound in an aqueous medium. Also, the the...

S. Saini * and R. Garg

IKG Punjab Technical University, Jalandhar, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.11(7).3474-82

3474-3482

2640

1425

21.

OPTIMIZATION OF PROCESS PARAMETERS FOR IMPROVED PRODUCTION OF BIO-ACTIVE METABOLITES BY ENDOPHYTIC FUNGUS CLADOSPORIUM CLADOSPORIOIDES ISOLATED FROM MANGROVE PLANT LUMNITZERA RACEMOSA LINN.

A study has been undertaken with an aim to isolate potent endophytic fungi from mangrove plant Lumnitzera racemosa Linn. Among the 10 different fungal strains isolated, one potent strain with broad-spectrum antagonistic activity was found. Basing on the morphological, cultural and molecular characteristics, the potent fungal strain was identified as Cladosporium cladosporioides. Production of bioa...

G. V. L. Bhavani and V. Muvva *

Department of Botany and Microbiology, Acharya Nagarjuna University, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(7).3260-67

3260-3267

2639

1299

67.

IN-VITRO EVALUATION OF ANTI-HELICOBACTER PYLORI ACTIVITY OF COMMERCIALLY AVAILABLE PROBIOTICS

Helicobacter pylori is a major etiological agent responsible for several gastric diseases such as gastritis, peptic ulcer disease, and gastric cancer. From the last two decades, standard triple therapy is mostly recommended for H. pylori eradication; however, its efficacy is restricted by antibiotic resistance. Hence, the present study aimed at exploration for novel therapeutic agents being warran...

G. Gupta, D. Bansal, A. Sharma, T. Ahmad, A. Sachdev and B. Kaur *

Department of Biotechnology, Punjabi University, Patiala, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5890-97

5890-5897

2637

1261

69.

ANTICOAGULANT AND FIBRINO(GENO)LYTIC PROTEASE FROM LEUCAS ASPERA

Leucas aspera is the medicinal plant commonly known as ‘Thumbai’ found all over India. It is being used in traditional medicine to treat cough, cold, diarrhea, inflammatory diseases, and paste of the plant that has been used to treat the wound to enhance the wound healing process. The plant is reported to have anti-inflammatory, analgesic, antidiarrheal, antimicrobial, antioxidant, and insecti...

V. Gubbiveeranna, C. G. Kusuma, C. K. Sumachirayu, S. Bhavana, H. Ravikumar and S. Nagaraju *

Department of Studies and Research in Biochemistry, Tumkur University, Tumakuru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(4).2470-76

2470-2476

2635

1139

46.

2D QSAR ANALYSIS OF DIPEPTIDE NITRILE BASED CATHEPSIN S INHIBITORS

Cathepsin S enzyme has been considered as an evolving target for the development of novel therapeutic agents for the treatment of numerous autoimmune disorders and other inflammatory diseases. Using TSAR 3.3 2D QSAR has been performed on a series of dipeptide nitrile nucleus. Attempts have been made to derive and comprehend a correlation between biological activity and the generated descriptors. T...

S. Kushwaha * and S. K. Paliwal

Faculty of Pharmaceutical Sciences, Rama University, Mandhana, Kanpur, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(6).3391-02

3391-3402

2635

1074

13.

NANOEMULSION: A PROMISING AND NOVEL NANOTHERAPEUTIC VEHICLE FOR TRANSDERMAL DRUG DELIVERY

Transdermal delivery of therapeutics has been identified by scientific researchers as an alternative choice of drug administration, owing to its unique and tremendous benefit over conventional and oral administrations, but its exploration has been limited because of the “skin barricade” as its major challenge. A special formulation that is capable of meeting up and overcoming its associated ch...

O. B. Oyelaja, E. O. Dare, D. P. Katare * and F. O. Oladoyinbo

Centre for Medical Biotechnology, Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(6).2636-48

2636-2648

2634

1347

27.

CHEMICAL COMPOSITION OF ESSENTIAL OIL OF EQUISETUM DIFFUSUM: A NOBLE SOURCE OF PHYTOL

Plants as a source of medicine have been inherited and are an important component of the health care system in India. Equisetum diffusum D. Don (Equisetaceae) is one of the medicinally important plants, which is a native species to the Himalayan Mountains. It is popularly known as Himalayan horsetail. The present endeavor deals with the exploration of the chemical composition of Himalayan E. diffu...

P. Takuli, K. Khulbe, P. Kumar * and C. Pant

Department of Botany, D.S.B. Campus, Kumaun University, Nainital, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5572-78

5572-5578

2634

1455