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DEVELOPMENT AND EVALUATION OF HYDROCORTISONE-LOADED NIOSOMAL GEL
Objective: The present research work was to formulate optimize and evaluate hydrocortisone-loaded niosomal gel for the management of rheumatoid arthritis. Method: Niosomal gel was successfully prepared by lipid-thin film hydration process and optimized by using 23 full factorial designs using three independent variables (tween 80 concentration, cholesterol concentration, and sonication time) and t...
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EVALUATION OF IN-VITRO ANTIFUNGAL POTENTIALITIES AND GC/MS SPECTROSCOPIC APPROACH OF CLEISTANTHUS COLLINUS (ROXB.) BENTH. EX. HOOK. F.
India is the home to the familiar plant Cleistanthus collinus (Roxb.) Benth. ex Hook. F (Euphorbiaceae) has great ethnomedicinal and therapeutic applications. The present study was designed to assess the phytochemical profile and investigate the antifungal effectiveness of leaf, bark and fruit extracts by using the agar well diffusion method. All crude extracts from leaf, bark, fruit and fractions...
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ANTI-DIABETIC ACTIVITY OF THE METHANOLIC EXTRACT OF SEEDS OF SYZYGIUM CUMINI IN STZ-INDUCED TYPE I DIABETES IN RATS
Background: Syzygium cumini (SC) usually acknowledged as Jamun. All components of the Jamun may keep used medicinally because of a wide range of diseases like cough, diabetes, dysentery and inflammation. Objectives: Present investigational on the anti-diabetic activity of the methanolic extract seeds of SC in STZ-induced Type I Diabetes in rats. Methods: Extracted SC was to be evaluated the toxici...
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LIP REPOSITIONING AS AN ADJUNCT TO THE TREATMENT OF EXCESS GINGIVAL DISPLAY: CASE SERIES
A smile is a basic and universal facial expression and is an interaction between the teeth, the lip, and the gingival outlines. The smile plays a significant role in the communication and appearance of an individual. As the esthetic demand increases, obtaining a “perfect smile” has become a major goal for many people of this generation. One of the most important features of dental and facial a...
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IN-VITRO AND IN-VIVO NEUTRALIZING POTENTIAL OF RAUVOLFIA SERPENTINA ROOT EXTRACT AGAINST BUNGARUS CAERULEUS VENOM
Snakebite is an international health hazard that needs attention in terms of effective management and better treatment to recover the health of the affected individuals and society. Tribal populations and folk therapists across the world have been using innumerable plants to treat snakebite difficulties. In the present study, the efficacy of aqueous extracts of Rauvolfia serpentina root for neutra...
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REVIEW ARTICLE: ANALGESIC ACTIVITY OF A POTENTIAL SOURCE OF MODERN MEDICINE
Recently, scientific investigations of medicinal plants using indigenous medical systems have attracted a lot of attention in international investigation. Nature has imparted our planet with an enormous wealth of medicinal plants known for bestowing and are highly esteemed worldwide as a rich source of therapeutic agents for the prevention and cure of diseases and ailments. Since their chemical ch...
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INSIGHTS INTO THE ROLES OF ANTIOXIDANTS IN CITRUS FRUITS
Citrus fruits are known for their nutritiousness. Role of vitamins and minerals play a major role in citrus fruits during plant-pathogen interactions. These fruits are the supreme fruit crops which contain flavonoids and phenolic compounds. These molecules benefit individuals who are all consuming and play an important role in fruit ripening and development. Mainly these molecules act as antioxida...
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ASSESSMENT OF ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF SECONDARY METABOLITES FROM LEAVES AND FRUIT EXTRACT OF GYMNOSPORIA MONTANA
Objectives: Gymnosporia montana (family Celeastraceae), important shrub which is widely reported in Gujrat, India. In this study, our major objective is to screen secondary metabolites of methanolic leaves and fruit extract and determining its antioxidant and anti-inflammatory potential of this shrub. Materials and Methods: Leaves and fruit extract were subjected to methanol followed by phytochemi...
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A REVIEW OF CLINICAL STUDIES IN TUBERCULOSIS REGISTERED IN THE CLINICAL TRIALS REGISTRY OF INDIA
Background: Currently, 23 drugs for treating drug-susceptible TB, MDR-TB, or latent TB infection are in Phase I, II, or III trials. Bedaquiline, Delamanid and Pretomanid are new approved drugs. Still, TB is more prevalent in many countries. So, ideally, the countries facing this problem should do extensive research. Aim: The aim of our study is to find the number of studies, their design, sponsors...
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TREATMENT STRATEGIES FOR NEURODEGENERATIVE DISEASES THROUGH IMPORTANT MEDICINAL PLANTS USED IN UNANI MEDICINE
Neurodegenerative diseases (NDs) that are characterized by progressive loss of functioning and structure of neurons are of great burden to the individuals and the society. With several hypotheses, the existent cause still remains a mystery for various NDs in healthcare. Protein degradation, inflammation, oxidative stress, environmental factor, mitochondrial defects, abnormal protein accumulation i...
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