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IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY EVALUATION OF SUCCESSIVE EXTRACTS OF ZIZIPHUS NUMMULARIA
Ziziphus nummularia is commonly found plant in dry regions of South Asia such as India, Pakistan. Z. nummularia contains numerous phytochemicals such as flavonouds, alkaloids that are responsible for numerous biological activities. In current study, elaborative pharmacognostic studies on the leaves of Z. nummularia were done for standardization purposes for future studies. The study includes morph...
1879
846
QUERCETIN LOADED POLY VINYL ALCOHOL- ALGINATE HYDROGEL ATTENUVATES INFLAMMATION
The flavonoid compound quercetin is widely acknowledged for its diverse biological properties including anti-inflammatory, antioxidant, anti-bacterial, anti-ageing, anticancer however the constraints like poor solubility, low bioavailability, lack of stability and decreased permeability limits its pharmacological applications. Hydrogel assisted delivery systems especially for transdermal delivery ...
1879
1308
IN-VIVO EVALUATION OF GLICLAZIDE SOLID DISPERSIONS INCORPORATED TABLETS FOR CONTROLLED DRUG RELEASE
Gliclazide is an anti-diabetic medication used to treat diabetes mellitus type 2.It suffers from deprived solubility, reduced drug dissolution, and bioavailability. The current paper is aimed to formulate and evaluate gliclazide solid dispersion with HP β Cyclodextrin for enhanced solubility and incorporate into controlled-release tablet formulation. Gliclazide solid dispersion (SD) was prepared ...
1878
984
GREENER SYNTHESIS OF CUO NANOCRYSTALS USING RAMBUTAN NEPHELIUM LAPPACEUM L. PEEL EXTRACT AND ITS ANTIBACTERIAL APPLICATIONS
Green synthesis of copper oxide nanocrystals was carried out via hydroxide precipitation using rambutan peel wastes. The successful formation of copper oxide nanocrystals was confirmed by X-Ray diffraction (XRD), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Atomic Force Microscopy (AFM) analysis. XRD analysis confirms the calculated average crystallite size of hig...
1878
1040
QUANTIFICATION OF SPIRONOLACTONE AND ITS IMPURITIES PRESENT IN PHARMACEUTICAL DOSAGE FORMS BY STABILITY-INDICATING HPLC METHOD
Spironolactone belongs to a group of medicine known as aldosterone antagonist used as sparing diuretic, Spironolactone (aldactone) is potassium -aspiring diuretic agent and has half-life of about 16 hours. Spironolactone one diuretics agents which increases renal excretion of water and solutes (mainly sodium salt). It is used mainly in the treatment of refractory edema in patients with congestive ...
1877
1119
NOVEL ANTI-DIABETIC POTENTIAL OF “SUGAR CARE” A MIRACLE DRINK EVALUATED ON HUMAN DIABETIC SUBJECTS
The herbal-based formulation “Sugar Care” a product of Miracle Drinks was assessed for an anti-diabetic property on 12 diabetic patients. Each patient was prescribed 15ml of Sugar Care (S10) morning and evening after meal and 15ml of cardiovascular care (S3) in the afternoon. Morning and night doses of sugar care were given along with 15ml of Liver Care (S4) and Renal Care (S5). After 30 days ...
1876
909
PRECLINICAL STUDY ON URINARY TRACT INFECTED EXPERIMENTAL RATS TREATED SPHAERANTHUS INDICUS L.
A model of ascending Urinary tract infection (UTI) in rats was developed to study the significance of antibacterial activity of Sphaeranthus indicus L. and compared with standard antibiotic ofloxacin as a positive control. This plant used in folk medicine as a remedy for urinary tract infections is belong to Asteraceae family. Outbred female wistar rats were used throughout the study and Escherich...
1875
988
PHYTOACTIVE AS CHELATORS OF IRON WITH THE POTENTIAL TO MITIGATE ITS SIDE EFFECTS AND ENHANCE IRON ABSORPTION
Iron deficiency anaemia afflicts a large proportion of the human population, compromising productivity and quality of life. Iron supplements are widely prescribed for treating anaemia. However, poor compliance due to side effects, particularly gastrointestinal side effects, remain a hurdle in alleviating the problem, leading to unabated high prevalence. Thus, a fresh look at novel approaches to ...
1875
1372
EVALUATION OF EFFICACY OF UNANI REGIMEN IN THE REHABILITATION OF POST STROKE HEMIPLEGIC GAIT: AN OPEN INTERVENTIONAL STUDY
Background: Stroke is the most frequent clinical manifestation of diseases of the cerebral blood vessels. Up to 90% of post-stroke survivors report one or more disabilities, including impaired walking. Physical rehabilitation and gait training with equipments are essential in the management of post stroke gait disability, however, these techniques are not amenable for hemiplegic patients because o...
1875
952
IN-VIVO ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACT FROM ROOTS OF SMILAX CHINA ON ALUMINIUM CHLORIDE INDUCED OXIDATIVE STRESS IN WISTAR RATS
To examine the antioxidant property of ethanolic extract of roots of Smilax china (EESC) on Aluminium Chloride Induced oxidative stress in Wistar rats. The phytoconstituents are extracted from the roots of S. china using ethanol, by hot continuous percolation method. The rats were divided into 5 groups (6 animals/ group) and treated with EESC (150 & 300 mg/kg of body weight) and piracetam (0.5...
1875
1034