Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
CATHARANTHUS ROSEUS AND PROSPECTS OF ITS ENDOPHYTES: A NEW AVENUE FOR PRODUCTION OF BIOACTIVE METABOLITES
Catharanthus roseus is a medicinal herb found in many tropical and subtropical regions around the world. This plant produces a diverse array of secondary metabolites that are pharmaceutically important like vinblastine and vincristine used as chemotherapeutic agents in the treatment of several types of cancers. Low yield of these vinca alkaloids from the plant in vivo and the challenges to meet th...
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AN OVERVIEW ON ARACHIS HYPOGAEA PLANT
The peanut or groundnut (Arachis hypogaea) is a species in the legume family (Fabaceae). There are different varieties like Virgina group, Spanish group, Runner group, Valencia group, Tennessee red and Tennessee white. Peanut consists of 30 essential nutrients and phytonutrients. Peanuts are a good source of vitamins & metals. Peanut hulls consist of crude fiber, cellulose, water, crude protei...
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ISOLATION OF β-SITOSTEROL & STIGMASTEROL AS ACTIVE IMMUNOMODULATORY CONSTITUENTS FROM FRUITS OF SOLANUM XANTHOCARPUM (SOLANACEAE)
General phytochemical screening of the aqueous extract of fruits of Solanum xanthocarpum (Solanaceae) revealed the presence of steroids, terpenes, phenolic compounds, saponins, fatty acids, alkaloids. Fractionation of aqueous extract and activity guided isolation resulted in isolation of two white crystalline powder which were subjected to physical, chemical and spectral identification usi...
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PHYTOCHEMICAL ANALYSES, ANTIBACTERIAL, IN VITRO ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF ETHANOLIC EXTRACT OF SYZYGIUM CUMINI (L.) SEED EXTRACT
Phytochemical constituents present in the aqueous and ethanolic extract of Syzygium cumini seeds were investigated which were found to be responsible for its medicinal efficacy. The major phytoconstituents present in S. cumini seeds were further determined by GCMS analysis which showed the presence of polyphenols, sesquiterpenes, n-alkanes. The antibacterial activity of ethanolic extract of S. cum...
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METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF EMPAGLIFLOZIN IN API
An accurate, precise and rapid RP-HPLC method was developed and subsequently validated for the determination of Empagliflozin in API. Better separation of the drug was achieved on Intersil column(150x40mm, 5 μm) with the mobile phase consisted of mixture of 0.01 M acetate buffer, methanol in ratio of (30:70v/v ) at flow rate of 2ml/min, with detection at 260nm using PDA detector. The retention...
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DEVELOPMENT AND VALIDATION OF A NOVEL STABILITY-INDICATING RP-HPLC METHOD FOR THE DETERMINATION OF EMPAGLIFLOZIN IN BULK AND PHARMACEUTICAL DOSAGE FORM
A novel stability-indicative of RP-HPLC method was developed and validated for the quantitative estimation of Empagliflozin in bulk drugs and pharmaceutical dosage form in the presence of degradation products. Chromatographic separation was achieved on an Intersil C18 (150mmx4.6mm, 5 μm) analytical column using mobile phase composition of methanol and acetonitrile in ratio of (50: 50 v/v) that w...
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ENCAPSULATION OF CURCUMIN IN SILVER NANOPARTICLE FOR ENHANCEMENT OF ANTICANCER DRUG DELIVERY
In the proposed work, enhancement of anticancer potential of curcumin extracted from Curcuma longa Linn. by encapsulated in the silver nanoparticle. Curcumin was extracted from Curcuma longa by Soxhlet method. Curcumin is a kind of poly phenols which was widely used because of its medicinal application. Curcumin shows poor solubility and low absorption rate therefore its silver nanoparticles was f...
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PELTOPHORUM PTEROCARPUM: CHEMICAL AND PHARMACOLOGICAL ASPECTS
The present work offers a review addressing the detailed chemistry and pharmacology of Peltophorum pterocarpum (belonging to Fabaceae family) regarded as one of the most significant plant species in traditional system of medicine. The plant is used in different parts of the world for the treatment of several ailments like stomatitis, insomnia, skin troubles, constipation, ringworm, insomnia, dysen...
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A REVIEW ON HEPATOPROTECTIVE ACTIVITY
Liver, the largest gland functioning as an organ of storage, manufacturing and biotransformation is a vulnerable target for injury. Chronic alcohol consumption, exposure to toxic chemicals and certain drugs like paracetamol, tetracycline, antitubercular drugs, chemotherapeutic agents, NSAIDS, damage the liver cells (hepatocytes) in long run. Drug induced liver injury is a major health problem, the...
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DESIGN AND EVALUATION OF TOPICAL HYDROGEL FORMULATION OF DICLOFENAC SODIUM FOR IMPROVED THERAPY
Topical gel preparations are intended for skin application or to certain mucosal surfaces for local action or transdermal penetration of medicament or for their emollient or protective action. Topical delivery of drugs can be achieved by incorporating drug into the gel matrix for effective delivery of drugs, thus avoiding first pass metabolism and for increased local action in pain management and ...
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