Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
EVALUATION OF EFFICACY AND SAFETY OF GEMIFLOXACIN IN CHRONIC BRONCHITIS PATIENTS
The study aimed to assess the efficacy and safety of Amoxicillin/Clavulanate 625 mg and Amoxicillin/Clavulanate 1 gram in chronic bronchitis patients. Chronic bronchitis, a type of COPD defined by a productive cough that lasts for 3 months or more for at least 2 years, other symptoms include wheezing and breathlessness, upon exertion. It is caused by recurring irritation to the epithelium of bronc...
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DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC ASSAY METHOD FOR DETERMINATION OF LORNOXICAM IN SELF EMULSIFYING DRUG DELIVERY SYSTEM (SEDDS) FORMULATION
The objective of the present work was to development and validation of stability indicating RP-HPLC assay by applying different stress degradation conditions on lornoxicam in Self Emulsifying Drug Delivery System (SEDDS) formulation. HPLC separation was achieved on analytical technique using C-18 column and mobile phase of Acetonitrile: Methanol (65:35, v/v) at a UV detector. The lornoxicam drug c...
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1354
ANTIBACTERIAL ACTIVITY OF SIX MEDICINAL PLANTS USED IN TRADITIONAL MEDICINE GROWING IN BANGLADESH
The antibacterial activity of the hexane, methanol, and water extracts of Tamarindus indica, Azadirachta indica, Cucumis sativus, Eucalyptus camaldulensis, Switenia mahagoni, and Psidium guajava extensively used in traditional medicine were investigated. The disc diffusion assay method was used for the evaluation of the antibacterial activity of these extracts against 11 bacteria species. Kanamyci...
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1408
HISTOPATHOLOGICAL EFFECT OF ETHANOLIC EXTRACT OF TRIDAX PROCUMBENS ON KIDNEY OF ALBINO RATS
Herbal drugs are emerging as a leading area for new drug discovery and development, and are being looked at seriously for health problem. Plants, especially used in Ayurvedic can provide biologically active molecules and lead structures for the development of modified derivatives with enhanced activity and or reduced toxicity. Exposure of toxicants manifests variety of pathological lesions in vari...
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1181
DEVELOPMENT AND OPTIMIZATION OF LIPOSOMAL KETOTIFEN FUMARATE DRY POWDER USING RESPONSE SURFACE METHODOLOGY
The aim of this study was to develop and optimize nano-liposomally entrapped ketotifen fumarate (KTF) loaded dry powder inhalation (DPI) formulation using response surface methodology (RSM). Based on the 33 full factorial design (33FFD), the mass ratio of KTF solution to soybean phosphatidylcholine (SPC94), KTF/ SPC94 to 0.5 M lactose solution that after lyophilization produce lyophilized liposoma...
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PROTECTION FROM HEPATIC ISCHEMIA AND IMPROVEMENT OF LIVER REGENERATION BY THUJA ORIENTALIS
Liver is a vital organ performing wide range of functions; oxidative damage is implicated in the pathogenesis of various liver disorders. Present study was aimed at evaluating protective ability of Thuja orientalis Linn against thioacetamide induced hepatotoxicity in rats. Thuja orientalis has been used in Ayurvedic medicine for the treatment of various disorders. Thuja orientalis has the biologic...
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1351
DEVELOPMENTS OF CARCINOGENESIS INDUCED BY ABNORMALITIES OF WNT GENES
In cancers, many signals were involved in self-renewal, differentiation and proliferation. Especially, Wnt signaling pathway plays crucial impact in stem cells and cancer development. Wnt genes were involved in the stimulation of Wt signaling pathway in stem cells development. Despite, mutation and overexpression of Wnt genes induced regulation of carcinogenesis. Out of 19 Wnt genes, each Wnt gene...
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SPECTROPHOTOMETRIC AND SPECTROFLUORIMETRIC DETERMINATION OF OXCARBAZEPINE IN PURE FORM AND PHARMACEUTICAL PREPARATION
Simple and sensitive spectrophotometric Method (A) and spectrofluorimetric Method (B) were described for the analysis of oxcarbazepine. The proposed methods were based on the oxidation of the drug with cerium (IV) ion in acidic medium with subsequent measurement of either the decrease in absorbance at 321 nm or the fluorescence intensity of the produced cerous (III) ion at 363 nm emission after ex...
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THE EFFECT OF VALERIAN ON THE PHARMACOKINETICS OF CARBAMAZEPINE IN HEALTHY RABBITS
This article aimed to evaluate the effect of valerian on a single dose kinetic of carbamazepine in rabbits. Five healthy male rabbits in a randomized, two-crossover design were enrolled in this study. Rabbits were divided into two groups; the first received a single dose of 100 mg carbamazepine (CBZ) suspension. The second group received CBZ 100 mg suspension concurrently with valerian (VAL) 25 mg...
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EFFERVESCENT BIOADHESIVE VAGINAL TABLET OF METRONIDAZOLE FOR BACTERIAL VAGINOSIS – DESIGN AND IN-VITRO EVALUATION
In the present study, the effort has been made to formulate the effervescent bioadhesive vaginal tablet of Metronidazole for localized treatment of Bacterial vaginosis. Among various bioadhesive polymers carbopol 934P, hydroxyl propyl methylcellulose K4M, methylcellulose, and sodium carboxymethyl cellulose were selected. Eight different formulations were made using a single polymer as well as a co...
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