Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
REVERSAL OF ROSIGLITAZONE HEPATOTOXICITY BY SILYMARIN ON RATS
The present study was undertaken to investigate the hepatotoxic potential of rosiglitazone- an oral hypoglycemic thiazolidenedione class of drug. The hepatotoxic potential of rosiglitazone was assessed in-vitro on isolated rat hepatocytes before subjecting to in-vivo studies. The in-vitro activity was measured by trypan blue exclusion assay and determination of liver marker enzymes. The hepatotoxi...
3685
1459
PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF AQUEOUS EXTRACT OF THE AERIAL PARTS OF VIBURNUM PUNCTATUM BUCH. – HAM. Ex. D. DON
The genus Viburnum punctatum Linn. Under the family Caprifoliaceae (formerly) and Adoxaceae (currently) consists of about 200 species throughout the world. Many of these species have been recognized for their medicinal properties from very early times of this century. The aerial parts of Viburnum punctatum was collected from Nilgiri hills, Tamilnadu, India and was authenticated by Dr. A. B. Rema...
3593
1552
TREATMENT OF DEEP AND SUPERFICIAL INFECTIONS OF CANDIDA-WHAT WE KNOW AND WHAT IS NEW?
Candidiasis or moniliasis is more common among the critically ill patients in Intensive Care Unit and in highly immunocompromised patients. This mini review explains the various risk factors for their acquirement and the various treatment options which were used in the past and the current new approaches used in the treatment of candidiasis in the different clinical settings...
3916
1488
EVALUATION OF PRESERVATIVE EFFECTIVENESS OF FERULIC ACID DERIVATIVES IN ALUMINIUM HYDROXIDE GEL- USP
The selected amide and ester derivatives of ferulic acid were subjected to preservative efficacy testing in an official antacid preparation, (Aluminium Hydroxide Gel-USP) against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Candida albicans and Aspergillus niger as representative challenging microorganisms as per USP 2004 guidelines. The selected derivatives were found to be effecti...
4440
1975
HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHIC DETERMINATION OF COLCHICINE IN PHARMACEUTICAL PREPARATIONS AND BIOLOGICAL FLUIDS
A simple and rapid high performance thin layer chromatographic (HPTLC) method was developed for the assay of colchicine in bulk drug, pharmaceutical preparations and biological fluids. The method has a linear range of 4 - 35 μg/ml. The limits of detection and quantification were 1 and 4 μg/ml respectively. The results obtained by the proposed method were compared statistically by means...
3627
1432
ANTI-HYPERGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF SOLANUM SURATTENSE ROOT
The ethanol extract of Solanum surratense(EESS)(Family: Solanaceae) root was investigated for its anti-diabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by administration of single dose of Alloxan monohydrate (150mg/kg). The ethanol extract of Solanum surratense at the dose of 200mg/kg and 400mg/kg, p.o. was administered as single dose per day to diabetes induced rats for ...
5125
1403
IDENTIFICATION OF INTER SPECIES GENETIC VARIABILITY BETWEEN TWO MORPHOLOGICALLY SIMILAR SPECIES OF WITHANIA THROUGH PROTEIN AND RAPD MARKERS
The two species of Withania i.e. Withania obtusifolia and Withania somnifera were usually misinterpreted because of their co-existence in mixed populations. The present investigation involves analyzed of interspecific relationship between these two species. A careful morphological, anatomic and phytochemical, identification of the two species has led to the findings that there was a slight variati...
3501
1730
FORMULATION AND CHARACTERIZATION OF CONTROLLED POROSITY OSMOTIC TABLETS OF ACYCLOVIR FOR TREATMENT OF HERPES SIMPLEX
The main objective of present work was to formulate and evaluate swellable controlled porosity osmotic tablets of Acyclovir for the treatment of herpes simplex. This formulation aims to release the drug in zero order pattern, increase bioavailability, reduce frequency of drug dosing and hence increased patient compliance. Acyclovir is a synthetic purine nucleoside analogue that is specially activa...
4806
1965
SERUM ELECTROLYTES CHANGES WITH ATHEROGENIC INDEX OF PLASMA IN HYPOTHYROID DIABETIC (TYPE-2) YOUNG MALES
Background: Atherogenic index of plasma, a newly emerging lipid parameter, has been employed only in a few studies of diabetics and not at all in hypothyroid type -2 diabetic young males with electrolytes imbalance. Methods: Association between diabetic hypothyroid and electrolytes with atherogenic index of plasma in 50 subjects and aged (25-45 years) matched healthy controlled were studied ret...
3762
2506
QSAR STUDIES ON NOVEL 1, 4-DIHYDROPYRIDINE DERIVATIVES
QSAR studies on N3, N5-diphenyl-1, 4-dihydropyridine-3, 5-dicarbohydrazides [2A-2D’] and 2, 6-dimethyl-1,4-dihydro-pyridine-3, 5-yl-bis[carbonyl-2-(phenyl)]pyrazolidine-3, 5-diones] [3A -3D’] were carried out. 3D chemical structures were given as input and desired molecular attributes and molecular indices were selected. Various molecular descriptors were studied using TSAR (Tools for Structur...
4367
1799