Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
ANALYTICAL CHARACTERIZATION OF A CONTROLLED RELEASE POLYMERIC SUSPENSION
Aims: Qualitative analysis of a mucoadhesive polymeric (Carbopol940) suspension of Norfloxacin was carried out with the aim of developing an oral controlled release gastro-retentive dosage form. Methods: The characterization of ultrasonicated formulation was performed by Fourier Transform Infrared Spectroscopy (FTIR), Raman Spectroscopy, X-ray powder diffraction (XRD) and Scanning electron micr...
4020
1381
DEVELOPMENT AND VALIDATION OF TWO SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF METRONIDAZOLE AND OFLOXACIN IN SUSPENSION
Two simple, sensitive, rapid, accurate and economical methods were developed for the estimation of Metronidazole and Ofloxacin in two component liquid dosage form. First method is based on the simultaneous equation and second method is based on Q-analysis (absorbance ratio method). Metronidazole has absorbance maxima at 318.0 nm and Ofloxacin has absorbance maxima at 294 nm in acetonitrile and dil...
5877
1763
FORMULATION OF SYNBIOTIC DRINK TO ENHANCE INTESTINAL GUT FLORA
The transition in diet has lead to an increase in lifestyle disorders and thereby increased dependency on wonder drugs. With increased drug discovery and marketing, there is a compelling trend towards large drug dosage. However, food is judged not only for its nutritive properties but also for its ability to improve the health and well being of consumers, thus leading to the advent of “FUNCTIONA...
4494
1752
IMPROVED EFFICIENCY AND REDUCED COSTS DURING INFUSION THERAPY WITH PREMIXED PREPARATIONS COMPARED TO FREEZE-DRYING POWDER
Background: An excessive medical expenditure is becoming a main barrier to good health for several people in China. Hence, there is a need to control this rising medical cost to reduce the financial burden placed on family and society in general. Objective: Our aim was to understand the expenses incurred during the use of two forms of infusion therapy- the premixed preparations and the freeze-d...
4234
1602
CONVOLUTION STUDY AND THE ALCOHOLIC BEVERAGE EFFECT ON LANSOPRAZOLE DELAYED-RELEASE CAPSULES AND APPLICATION OF SIMILARITY FACTOR TO TWO-STAGE IN – VITRO DISSOLUTION PARADIGM
Lansoprazole, a proton pump inhibitor, is used to treat ulcers in the stomach and duodenum. In order to protect this acid labile drug from being degraded in the gastric medium, the marketed oral dosage forms are formulated into delayed release pellets and tablets. The aims of this research were (1) to investigate the principal site of drug release and absorption rate between an over-the-counter (O...
5438
4284
IN – VIVO CONFIRMATION OF A 49.6 KDA PROTEIN PILI OF HELICOBACTER PYLORI TO PREVENT DESTRUCTION OF GASTRIC CELLS AGAINST LIVE HOMOLOGOUS BACTERIA IN MICE
Peptic ulcers is one of the major gastrointestinal disorder in human being that generally associated with the infection of Helicobacter pylori, a gram-negative microaerophilic bacterium in stomach. It is also linked to the development of the stomach cancer. The aim of this study was to investigate the in vivo properties of the sub-unit pili proteins with molecular weight of about 49,6 kDa in m...
3943
1722
DESIGN, SYNTHESIS AND ANTIMICROBIAL EVALUATION OF NOVEL 1-(2-(4-FLUORO BENZYLTHIO)PYRIMIDIN-4-YL-AMINO)-4-(SUBSTITUTED PHENYL)AZETIDIN-2-ONES
A series of novel 1-(2-(4-fluorobenzylthio)pyrimidin-4-yl-amino)-4-(substituted phenyl)azetidin-2-one analogues (3a-e) were synthesized starting from 2-thiouracil. Reaction of 2-thiouracil with 4-fluorobenzylchloride gave 2-(4-fluorobenzylthio) pyrimidin-4(3H)-one which on chlorination with POCl3 yielded 2-(4-fluorobenzylthio)-4-chloropyrimidine. Further reaction of compound 2-(4-fluorobenzylthio)...
3744
1516
FORMULATION DEVELOPMENT OF LYOPHILIZED FLOATING BEADS CONTAINING GINGER EXTRACT AND NIGELLA SATIVA OIL
Lyophillized floating beads have been investigated as a possible gastro-retentive dosage forms containing Ginger (Zingiber Officinalis) extract ( ZOE) and Nigella Sativa oil (NSO). Emulsion gelation method was used in preparation of ZOE-NSO entrapped floating alginate beads. Drug content and floating properties of the beads were found to be satisfact...
4779
1985
SIMULTANEOUS ESTIMATION OF SULFAQUINOXALINE SODIUM AND AMPROLIUM HYDROCHLORIDE BY RP- HPLC.
A new RP-HPLC method was developed and validated for the simultaneous determination of amprolium hydrochloride and sulfaquinoxaline sodium in a powder dosage form. The chromatographic separation was achieved by isocratic mode with Phosphate buffer and Acetonitrile (30:70; v/v), as mobile phase and using C-18 RP-Amide (25.0cm × 4.6 mmi.d, 5µ particle size) as stationary phase, with a flow rat...
5689
3228
SYNTHESIS OF MACROCYCLIC LIGANDS AND THEIR COBALT(II) COMPLEXES SPECTRAL CHARACTRIZATION AND ANTIMICROBIAL STUDIES
Complexes of Co(II) with macrocylic ligands i.e., 2, 3, 9, 10 tetraphenyl – 1, 4, 8, 11 – tetraazacyclotetradeca – 1, 3, 8, 10 tetraene (BDP), 2, 4, 10, 12 – tetramethyl – 1, 5, 9, 13 tetraazacyclohexadeca 1, 4, 9, 12 tetraene (ADP), 2, 3, 9, 10 tetramethyl 1, 4, 8, 11 tatraazatetredeca – 1, 3, 8, 10 tetraene (DDP) have been synthesized. All these complexes were characterized by elemen...
4053
1937