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SYNTHESIS AND CHARACTERIZATION OF SILVER NANOPARTICLES AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF LEAF, SEED AND FRUIT EXTRACTS OF SYZYGIUM CUMINI L.
Syzygium cumini L. belongs to the family Myrtaceae is one of the widely used medicinal plants in the treatment of various diseases particularly diabetes. The present study has been focused on the synthesis of silver nanoparticles of leaf, seed and fruit extracts of S. cumini and to observe their antimicrobial activity. The synthesized nanoparticles were characterized by performing UV-Vis spectroph...
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ANTI-DEPRESSANT POTENTIAL OF MUSIC THERAPY
Depression should be recognized as a clinical syndrome that is characterised by a cluster of emotional, behavioural, and cognitive features. The prevalence of depression is consistently high worldwide, and is associated with considerable morbidity. Music is one of the oldest and most basic socio-cognitive domains of the human species. Music Therapy is growing as a profession globally, both in quan...
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IMMUNOHISTOCHEMICAL DETECTION OF CASPASE 8 EXPRESSION AND APOPTOTIC INDEX ACTIVITIES OF CALVATIA CRANIIFORMIS CRUDE EXTRACT IN BALB/C MICE INOCULATED WITH H22 CELLS
Objectives: To identify Immunomodulatory, apoptosis induction and anticancer activities of aqueous and alcoholic extracts of Calvatia craniiformis regarding the size of tumor mass and immunohistochemical detection of caspase 8 expressions and apoptotic index in mice inoculated with H22 mouse hepatocellular carcinoma cells as therapeutic experimental system for human hepatocellular carcinom...
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INTERPRETATION OF QUALITY OF LIFE OUTCOMES AMONGST END STAGE RENAL DISEASE PATIENTS IN SELECTED HOSPITALS OF MALAYSIA
The concept of Health-related quality of life takes into account about patient well-being as expressed by both physical and psychological domains of health. The relevance of this concept in end stage renal disease patients has been well established and can be used for routine treatment of patients with renal failure. It is of deemed interest to compare health and wellness of end stage renal diseas...
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DEVELOPMENT AND IN VITRO EVALUATION OF ONCE DAILY CARBAMAZEPINE MATRIX TABLET FROM HYDROPHILIC POLYMERS
The purpose of study was to develop and characterize once daily extended release matrix tablets of Carbamazepine (CBZ), an antiepileptic drug. Tablets were prepared by wet granulation method. Methocel K15M CR and Methocel K100LV CR polymers were used as rate retarding agents in fourteen formulations. The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, compre...
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PHYTOCHEMICAL INVESTIGATION, ANALGESIC AND ANTIPYRETIC ACTIVITIES OF ETHANOLIC EXTRACT OF KARIYAT
An ethanolic extract of Kariyat (Andrographis paniculata) was prepared by using Soxhlet extractor. Kariyat ethanolic extract (KEE) was subjected for phytochemical investigations and screened for analgesic and antipyretic activities in experimental animals. High performance thin layer chromatography (HPTLC) and gas chromatography mass spectrometry (GC-MS) investigations indicated presence of steroi...
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ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF HEARTWOOD OF BIJASAR (PTEROCARPUS MARSUPIUM ROXB.) IN STREPTOZOTOCIN-NICOTINAMIDE INDUCED TYPE 2 DIABETIC RATS
The antidiabetic potential of ethanolic extract of bijasar (Pterocarpus marsupium Roxb.) heartwood was evaluated in the streptozotocin-nicotinamide induced type 2 diabetic model. Graded doses of the ethanolic heartwood extract were administered to normal and experimental diabetic rats for 12 days. Significant (p < 0.05) reduction in fasting blood glucose levels were observed in the normal as we...
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REVIEW ON NON-VIRAL DELIVERY SYSTEMS FOR siRNA
The emergence of RNAi, has found new horizons in siRNA as drug molecule. This technology offers a great promise in the achieving efficient treatment. There is a demand for designing efficient siRNA delivery systems/ vehicles that can achieve targeted delivery and replicate the invitro success. The siRNA delivery system selection is based on target cell type. The siRNA delivery systems are catego...
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SAFETY AND MULTIPLE DOSE PHARMACOKINETICS OF PALIPERIDONE ER IN INDIAN SCHIZOPHRENIC PATIENTS
Paliperidone is a new active substance, belonging to the class of atypical antipsychotic, and is the active metabolite of a well-known active substance, risperidone that has been used for the last 3 years. A randomized, double-blind, multicentric, study to evaluate the safety and efficacy of Paliperidone ER compared to Olanzapine in patients with Schizophrenia was conducted in Indian schizophrenic...
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EVALUATION OF WOUND HEALING ACTIVITY OF LEAF EXTRACT OF DODONAEA VISCOSA JACQ INALLOXAN INDUCED DIABETIC WISTAR ALBINO RATS
The present study was undertaken to evaluate the wound healing activity of leaf extract of Dodonaea viscosa Jacq in diabetic wistar albino rats. Wound is defined as a loss or breaking of cellular and anatomic or functional continuity of living tissue. Normal wound healing response begins the moment the tissue is injured. Wound healing is the process of repair that follows injury to the skin and ot...
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