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EVALUATION OF WOUND HEALING ACTIVITY OF LEAF EXTRACT OF DODONAEA VISCOSA JACQ INALLOXAN INDUCED DIABETIC WISTAR ALBINO RATS
The present study was undertaken to evaluate the wound healing activity of leaf extract of Dodonaea viscosa Jacq in diabetic wistar albino rats. Wound is defined as a loss or breaking of cellular and anatomic or functional continuity of living tissue. Normal wound healing response begins the moment the tissue is injured. Wound healing is the process of repair that follows injury to the skin and ot...
4091
1813
ANTIOXIDANT POTENTIAL OF Mn2+ IN THE HUMAN EJACULATED SPERMATOZOA UNDER OXIDATIVE STRESS
Reactive oxygen species (ROS) formation from fertile volunteer donor measured by thiobarbuteric acid reactive substances (TBARS). Spermatozoal suspension was treated or not with nicotine and supplemented or not with Mn2+. The same protocol followed when we used ferrous ascorbate promoter system and calculates the Cmax and kc value of the reaction using Lineweaver-burk double reciprocal plot. For c...
4091
2072
SCREENING OF MARINE SOILS FROM BAY OF BENGAL NEAR CHIRALA COAST OF ANDHRA PRADESH FOR ISOLATION OF LIPOLYTIC ACTINOBACTERIA AND CHARACTERIZATION OF THE MOST POTENT ISOLATES
Three marine soil samples collected at various seashores of the Bay of Bengal near Chirala Coast of Andhra Pradesh were screened for the isolation of lipolytic Actinobacteria by tributyrin agar clearing method. The isolates were cultured under submerged fermentation conditions and assayed for their extra cellular lipase producing capabilities using olive oil as substrate. Enzyme profiling of the s...
4091
1917
SYNTHESIS OF MACROCYCLIC LIGANDS AND THEIR COBALT(II) COMPLEXES SPECTRAL CHARACTRIZATION AND ANTIMICROBIAL STUDIES
Complexes of Co(II) with macrocylic ligands i.e., 2, 3, 9, 10 tetraphenyl – 1, 4, 8, 11 – tetraazacyclotetradeca – 1, 3, 8, 10 tetraene (BDP), 2, 4, 10, 12 – tetramethyl – 1, 5, 9, 13 tetraazacyclohexadeca 1, 4, 9, 12 tetraene (ADP), 2, 3, 9, 10 tetramethyl 1, 4, 8, 11 tatraazatetredeca – 1, 3, 8, 10 tetraene (DDP) have been synthesized. All these complexes were characterized by elemen...
4090
1956
ANTIDIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF SEMECARPUS ANACARDIUM (LINN.) STEM BARKS IN NORMAL AND ALLOXAN INDUCED DIABETIC RATS
The present study was designed to evaluate antidiabetic effects of ethanolic extract of Semecarpus anacardium (SA) stem barks in normal and alloxan induced diabetes rats. The antidiabetic effect of extract was evaluated investigated by measuring fasting blood glucose level and oral glucose tolerance test (OGTT) in normal and alloxan induced diabetes animal models. Here metformin (150 mg/kg) was us...
4090
1607
DEVELOPMENT AND IN VITRO EVALUATION OF FLOATING DRUG DELIVERY SYSTEM OF VERAPAMIL HCl
Gastro retentive controlled release drug delivery system of Verapamil HCl was formulated to increase the gastric retention time of the dosage form with controlling the drug release pattern. Different grades of hydroxy propyl methyl cellulose derivatives; Methocel K4M and Methocel K15MCR were incorporated for their gel forming properties. Tablet buoyancy was achieved by incorporating a mixture of g...
4090
1648
DEVELOPMENT AND IN VITRO EVALUATION OF ONCE DAILY CARBAMAZEPINE MATRIX TABLET FROM HYDROPHILIC POLYMERS
The purpose of study was to develop and characterize once daily extended release matrix tablets of Carbamazepine (CBZ), an antiepileptic drug. Tablets were prepared by wet granulation method. Methocel K15M CR and Methocel K100LV CR polymers were used as rate retarding agents in fourteen formulations. The granules were evaluated for angle of repose, loose bulk density, tapped bulk density, compre...
4090
1694
EVALUATING HYPOLIPIDEMIC POTENTIAL OF KASNI SEED (CICHORIUM INTYBUS) PREPARATIONS IN NEWLY DIAGNOSED PATIENTS OF METABOLIC DISORDER
Objective: To evaluate hypolipidemic potential of Kasni (Cichorium intybus) seed preparations combined with oral hypoglycemic agent in treatment of patients of newly diagnosed type 2 DM. Methods: Newly diagnosed 90 patients of Type2DM, age 35-65years, of either sex were divided into 3 groups. Each group having 30 patients (19 male and 11 females) matched with each other in terms of age and sex. In...
4090
1726
DESIGN AND EVALUATION OF AMOXICILIN TRIHYDRATE FLOATING GRANULES PREPARED BY MELT GRANULATION TECHNIQUE
The purpose of this study was to design and evaluate Amoxicillin trihydrate floating granules by melt granulation technique using Gelucire 43/01 and Campritol 888 ATO as lipid carriers. Polymers HPMC K4M and Ethyl Cellulose as release rate modifiers. The granules were evaluated by FTIR studies, differential scanning calorimetry, Scanning Electron microscopy, drug content, in vitro floating ability...
4090
1978
PREVALENCE OF PATHOGENIC ORGANISMS IN MEAT SAMPLES OF ONGKHARAK NAKHONNAYOK THAILAND
Globally, foodborne pathogens are the origin of diseases and deaths. To prevent the foodborne pathogens billions of dollars spending. Coliforms level, psychrotrophs mesophiles, E. coli, and Staphylococcus aureus, are routinely assessed to determine microbial safety, sanitation conditions, improper hygiene in poultry carcasses. Thai-population consumes more broiler meat due to its availability and ...
4090
1410