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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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26.

SCREENING OF ANTI-HYPERLIPIDEMIC ACTIVITY OF METHANOLIC EXTRACT OF LAGERSTROEMIA SPECIOSA (LINN.) PERS. LEAVES

The present study was designed to investigate the hypolipidemic activity of the methanolic leaf extract of Lagerstroemia speciosa Linn. Plant extract was tested in fat diet induced hyperlipidemic rat models. Methanolic extracts of leaves of Lagerstroemia speciosa Linn. were administered in doses of 250mg/kg and 500mg/kg/day for one week. The obtained results reveal that methanolic leaf extract (LM...

R. L. Koduru* and V. I. Varma

Department of Pharmaceutical Chemistry, Vignan Pharmacy College, Vadlamudi, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(1).214-17

214-217

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16.

IN-VITRO ASSESSMENT, ISOLATION AND SPECTRAL ANALYSIS OF THE CHLOROFORM FRACTION OF DIOSPYROS KAKI FRUIT

Persimmon (Diospyros kaki Linn.), which belongs to the Ebenaceae family, have numerous bioactive compounds such as polyphenols, dietary fiber, carotenoids and minerals. This fruit possesses hypolipidemic and antioxidant properties and can be used in anti-atherosclerosis diets. The present paper reveals the phytochemical screening, Antioxidant, Anti-inflammatory activity and GC-MS Spectral analysis...

B. Vanitha *and B. Duraisamy

Department of Pharmacognosy and Phytopharmacy, JSS College of Pharmacy, Ooty, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(1).140-49

140-149

3883

1760

08.

FICUS BENJAMINA: PHYTOCHEMICAL AND PHARMACOGNOSTIC PERSPECTIVE

In the present study, phytochemical and pharmacological properties of species of F. benjamina have been discussed. The phytochemical and pharmacological properties correlate with various active constituents of the plant. Ficus belongs to the Moraceae family, found in Asia and Australia, and widely distributed in tropical and subtropical areas, including more than 800 species. The genus Ficus const...

Puneet Kaur, Rajiv Sharma * and Supriya Agnihotri

University Institute of Pharma Sciences, Chandigarh University Gharuan-Mohali, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.14(1).71-79

71-79

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67.

FORMULATION AND EVALUATION OF PROGRAMMED RELEASE OCULAR INSERTS OF MIZOLASTINE

The main objective of this study was to prepare controlled release matrix type ocular inserts of mizolastine for the treatment of seasonal allergic conjunctivitis.The films were prepared by solvent casting technique using Eudragit RL100 and RS100 in different ratios with dibutylphthalate as the plasticizer. The films were evaluated for the physicochemical parameters. In-vitro studies were carried ...

Hema Bansal, Sadhna Khatry* and Sandeep Arora

Chitkara College of Pharmacy, Chitkara University, Rajpura-140401, Punjab, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).497-01

497-501

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43.

THE POSSIBLE PROTECTIVE EFFECT OF FRESH BEETROOT JUICE AGAINST PARACETAMOL INDUCED HEPATOXICITY IN ADULT ALBINO RATS

Hepatotoxicity in the form of acute liver failure is a serious side effect of several drugs most importantly paracetamol. Beetroot main ingredients are nitrate, betalains, phenolics and ascorbic acid, which are responsible for its protective against oxidative stress and inflammation. Aim: This study assessed the possible protective effect of beetroot against liver toxicity induced by paracetamol. ...

A. Al-Qtaitat *, A. Al-Maathidy, S. S. Farhan, G. Almuhaisen and J. A. M. Alzyoud

Department of Anatomy and Histology, Faculty of Medicine, Mutah University, Karak, Jordan.

DOI: 10.13040/IJPSR.0975-8232.11(2).844-52

844-852

3882

1256

48.

ATTENUATION OF HYPERGLYCEMIA AND OXIDATIVE STRESS IN STREPTOZOTOCIN-INDUCED DIABETIC RATS BY AQUEOUS EXTRACT OF AVERRHOA BILIMBI LINN FRUITS

In the present study, the antidiabetic and antioxidant effect of aqueous extract of Averrhoa bilimbi Linn (ABAE) fruits were evaluated. Diabetes mellitus was induced in male Sprague Dawley rats by a single intraperitoneal injection of streptozotocin (40 mg/kg body weight). Oral administration of aqueous extract of Averrhoa bilimbi Linn (ABAE) (50mg/kg body weight) and metformin (100 mg/kg body wei...

Surya B. Kurup* and S Mini

Department of Biochemistry, University of Kerala, Kariavattom, Trivandrum, Kerala, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(11).4979-86

4979-4986

3880

1751

5.

NOVEL NUCLEAR RECEPTOR SUPER FAMILY DATABASE

The objective of the project is to develop a comprehensive database of Nuclear Receptor (NR) Superfamily-Ligand. Nuclear Receptor Superfamily represents one of the most important families of drug targets in pharmaceutical development. Nuclear Receptor) Superfamily-Ligand is a novel public NR-related chemical genomic database that is primarily focused on the correlation of information between NRs a...

Akshay A. Bhat, Vinay Sridhar, Hemanth Kumar K., Abhilash M.*

UST Global, Technopark, Trivandrum, Kerala, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(10).41-49

41-49

3880

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45.

DEVELOPMENT OF A POLYHERBAL CAPSULE FOR THE TREATMENT OF HYPERLIPIDAEMIA

Hyperlipidaemia is mentioned as one of the life-style-related diseases as much as so for diabetes. In the present study an attempt was made to develop herbal capsules, which are containing the extract of Murraya koenigii and Achyranthus aspera. One of the major concerns in designing new formulation is that the active ingredient should be compatible with all the excipients and packaging material co...

P. K. Sharma *, R. P. Singh and S. Jain

Department of Pharmaceutical Sciences, Suresh Gyan Vihar University, Jaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.9(6).2500-06

2500-2506

3880

1418

28.

NON-TARGETED ANALYSIS AND CYTOTOXIC ACTIVITY OF HAMELIA PATENS JACQ.

In the present study we have done non-targeted analysis of extract from Hamelia patens Jacq. by GC/MS and estimated the inhibitory concentration (IC50) of the extract in three human tumor cell lines MCF-7, H-460 and SF-268. Hamelia patens is an herbaceous perennial plant of family Rubiaceae. Parts of the plant are used in Peruvian and Mexican folk-medicine. Dried leaves of Hamelia patens were extr...

S. Kumar, R. Bodla*and R. Kant

Department of Pharmaceutical Chemistry, Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), New Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.9(3).1093-99

1093-1099

3879

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39.

PHYTOCHEMICAL ANALYSIS AND IN-VITRO ANTICANCER ACTIVITY OF DURANTA ERECTA L. (VERBENACEAE)

The aim of the present work is the evaluation of anticancer activity of Duranta erecta L. stem extracts and also an investigation of the phytoconstituents from the different extracts of the plant. Chloroform, ethyl acetate, methanol and aqueous extracts of Duranta erecta L. stem were tested for their anticancer activity on three cancer cell lines, i.e., MCF-7 (Breast), HL-60 (Leukemia), and HT-29 ...

A. S. Wagh * and S. R. Butle

Department of Pharmacognosy, School of Pharmacy, S.R.T.M. University, Nanded, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2941-46

2941-2946

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