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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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41.

STUDIES ON ANTIULCER ACTIVITY OF ESSENTIAL OIL OF CALAMINTHA OFFICINALIS MOENCH.

The present study was undertaken to determine the anti-ulcer potential of Calamintha officinalis Moench, a standardized oil of Calamintha officinalis Moench, commonly known as Calamint. Effect of various doses (0.4ml/kg and 0.8ml/kg,) of Calamintha officinalis Moench. oil was studied on gastric ulcers in pylorus ligation, Diclofenac sodium induced gastric mucosal injury in rats. Anti-ulcer activit...

Mohini Verma*, R. Irchhaiya, P. P. Singh, Deepak Kailasiya and Vinod Kanaujia

Department of Pharmacognosy, Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India

DOI: 41. http://dx.doi.org/10.13040/IJPSR.0975-8232.2(10).2733-36

2733-2736

3846

1728

37.

DIFFERENCE BETWEEN NATIVE AND MUTANT RHIZOBIUM ON GROWTH OF VIGNA MUNGO L.

The present study, carry out the use of plant growth promoting rhizobacteria, were used to improve the yield in crop. The Rhizobium strains isolated from legumes plant Mimosa pudica L and this strain was mutated by using UV radiation. The plant growth hormones were detected by native as well as mutant Rhizobium strains by paper chromatography techniques. The same strains use in conducted to green ...

Shijila Rani AS, P. Parthiban * and V. Mahesh

Department of Microbiology, Marudupandiyar College, Vallam, Thanjavur, Tamilnadu, India

DOI: 10.13040/IJPSR.0975-8232.7(9).3848-51

3848-51

3846

1670

26.

PROTECTIVE EFFECT OF COCCINIA INDICA LEAF EXTRACT AGAINST ALCOHOL COMBINED WITH CARBON TETRACHLORIDE AND PARACETAMOL INDUCED LIVER DAMAGE IN RATS

Liver is a major metabolic organ affected by various toxins and chemicals. So  the potential therapeutic agent is needed for the  treatment of liver diseases. Natural products are the best source of remedies for the treatment of  all diseases.The aim of our study was to investigate the effect of leaf extract of Coccinia indica against Alcohol combines with CCl4 and Paracetamol induced hepatotox...

C. Maheswari *, . Babu and Meenakshi

Assistant Professor, Department of Pharmacology, R.V.S.College of Pharmaceutical Sciences, Sulur, Coimbatore-641402,Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(10).2660-64

2660-2664

3843

1863

25.

DESIGN OF EXPERIMENT UTILIZATION TO DEVELOP AND VALIDATE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY TECHNIQUE FOR ESTIMATION OF PURE DRUG AND MARKETED FORMULATIONS OF ATORVASTATIN IN SPIKED RAT PLASMA SAMPLES

A novel method of estimation and validation of Atorvastatin by Reverse Phase-High Performance Liquid Chromatography coupled with Ultra-violet detection was developed which had high potential in determining drug concentration in rat plasma samples during preclinical studies. Atorvastatin being >99% protein bound, exhibits great challenge in getting extracted from plasma samples. Hence, by treati...

M. Mathur and V. Kusum Devi *

Department of Pharmaceutics, Al-Ameen College of Pharmacy, Near Lalbagh Main Gate, Hosur road, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.8(4).1708-16

1708-1716

3842

1586

45.

EMBLICA OFFICINALIS ENHANCES CARDIAC TISSUE REGENERATION IN TADPOLES OF THE FROG RANA CYANOPHLYCTIS (SCHNEIDER)

Emblica officinalis and its derivative (Ascorbic acid) have profound effect on development and regeneration and are widely used in the Indian System of medicine for the treatment of different type of disease. Here, we discussed the comprehensive account of the effect of aqueous extract of the fruit of E.officinalis with special reference to cardiac tissue regeneration in frog tadpoles. E.officinal...

Govind Kumar Gupta* and O.P Jangir

Department of Biotechnology, IASE Deemed University, Sardarshahr, Rajasthan, India

DOI: 10.13040/IJPSR.0975-8232.6(9).4026-35

4026-35

3841

1563

30.

PERFORMANCE OF ASSOCIATION RULES FOR DENGUE VIRUS TYPE1 AMINO ACIDS USING AN INTEGRATION OF TRANSACTION REDUCTION AND RANDOM SAMPLING (TRRS) ALGORITHM

Association rule mining is the recent research area in data mining. Frequent Itemset Mining techniques is one of the prominent techniques in pattern mining. In this system frequent itemset mining is used to find the frequent amino acids patterns in Dengue Virus Type1 data set. This system uses an integration of Transaction Reduction and Random Sampling (TRRS) approach to identify the frequent patt...

D. Kerana Hanirex *, K. P. Thooyamani and V. Khanaa

Bharath University,Chennai, Tamilnadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(6).2578-87

2578-2587

3841

1521

45.

TRENDS IN ANTIEPILEPTIC DRUGS PRESCRIPTION PATTERN AMONG PATIENTS VISITING A TERTIARY CARE CENTER

The objectives were to observe the drug pattern of epileptic patients with their seizure type, to analyze the type of therapy received by the patients, to observe if epileptic patients are receiving an appropriate dose, to identify the side effects in epileptic patients associated with drug treatment and to observe the cost of conventional and newer antiepileptic drugs (AED’s). This was a cross-...

K. Gayathri *, R. M. Shireen, V. Lalasa, A. Suresh, G. Andhuvan and R. S. Iyer

Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.11(6).2914-19

2914-2919

3841

1361

26.

STABILITY-INDICATING LIQUID CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS DETERMINATION OF ATAZANAVIR AND RITONAVIR IN PHARMACEUTICAL FORMULATION

A simple, rapid, precise and accurate isocratic reversed-phase stability-indicating HPLC method was developed and validated for the simultaneous determination of Atazanavir (AT) and Ritonavir (RT) in commercial tablets. The method has shown adequate separation for AT, RT from their degradation products. Separation was achieved on a Hypersil BDS-C18, 5 μm, 125 mm × 4.6 mm i.d. column using a...

P. Saritha*, V. Girija Sastry, A. Vijaya Lakshmi and E. Veeraiah

University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam 530 003, Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.4(7).2659-66

2659-2666

3840

2076

23.

NOVEL 2 – AMINO – N’ – (2-OXOINDOLIN – 3 – YLIDENE) BENZO [d] OXAZOL – 5 -CARBOHYDRAZIDES AS ANTI-INFLAMMATORY AGENTS

In the present work , novel 2-Amino-N'-(2-oxoindolin-3-ylidene) benzo[d]oxazole-5-carbohydrazides were synthesized and  evaluated for In-vivo anti-inflammatory activity by carragenan induced rat paw edema method and were known to exhibit promising anti-inflammatory activity at a  dose of 30mg/kg bw. Compounds D2, D3, D5 and D8 were found to be comparatively potent with the standard Indomethacin....

A. Lavanya *, Arunadevi Parlapalli, Manasa Ciddi and Sarangapani M

University College of Pharmaceutical Sciences, Kakatiya University, Warangal, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(1).212-18

212-218

3839

2248

44.

DEVELOPMENT AND IN-VITRO EVALUATION OF FLOATING MICROSPHERES OF 5-FLUOROURACIL

Objective of the present study was to prepare and evaluate floating Microspheres using different ratio of ethylcellulose to control the release rate of 5-Fluorouracil (5-Fu) which was taken as a model drug. The microspheres were prepared by the modified emulsion solvent diffusion technique using different ratio of ethanol (ETN) and acetone (ACTN) as solvent system. To study the morphology of micro...

P. Bhardwaj*, R. Singh and A. Swarup

Adarsh Vijendra Institute of Pharmaceutical Sciences, Babu Vijendra Marg, Gangoh, Saharanpur- 247 341, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).934-41

934-941

3839

1609