Most Popular
ANALYSIS OF VARIABLES INVOLVE IN RHEUMATOID ARTHRITIS DIAGNOSIS USING LOGISTIC REGRESSION
Rheumatoid Arthritis (RA) is a auto-immune disease in which body mistakenly considers some parts of its own system as pathogens and attacks them. RA is a chronic systemic inflammatory illness with prevalence of approximately 0.75% in India. It leads to irreversible joint damage and systemic complications. It is associated with substantial morbidity and increased mortality Better understanding of i...
3895
1469
MICROWAVE ASSISTED ISOLATION OF MUCILAGE FROM THE TRICHOSANTHES DIOICA FRUIT
A microwave assisted extraction technique was developed to optimize the extraction of mucilage from the fruits of Trichosenthes dioica plant. Materials and Methods: the plant has been extracted by conventional and microwave assisted methods for the isolation of mucilage. Results and Discussion: Microwave extraction at 320 W intensity and 20 min heating duration, 84.92% increase in the yield of muc...
3894
1544
PREPARATION AND IN-VITRO CHARACTERIZATION OF FLOATING MICROSPHERES OF NATEGLINIDE
Gastric residence time of oral controlled release system such as microspheres is increase by different techniques such as floating and mucoadhesive system. The objective of present investigation was to formulate floating microspheres of Nateglinide in order to increase gastric residence time, increased bioavailability and to reduce dose frequency of drug molecule. Novel o/w emulsion solvent diffus...
3894
1747
CHEMICAL PROFILING, ADME PREDICTION OF BOERHAVIA DIFFUSA LINN. AND CRATEVA NURVALA BUCH. HAM IN THE MANAGEMENT OF UROLITHIASIS
Background: This study was carried out to investigate qualitative and quantitative phytochemical analysis and free radical scavenging activity of Boerhavia diffusa (root) and Crateva nurvala (bark) along with certain computational ADME (Absorption, Distribution, Metabolism, Excretion) parameters of compounds analyzed from Boerhavia diffusa (root) and Crateva nurvala (bark). Methods: The dried powd...
3894
1606
QUALITY BY DESIGN: A PRE-REQUISITE FOR PHARMACEUTICAL DEVELOPMENT
Quality by Design (QbD) is an essential part of modern pharmaceutical development. QbD is a requisite for the design and development process for the pharmaceutical industry. QbD assists and encourages both the industries and FDA to inculcate a proactive, scientific and risk-based approach in the process and product development. It is based on a concept of building quality right from the start of t...
3893
2009
EFFECT OF MORINGA OLEIFERA LAM. ROOT ON COLONIC MOTILITY DISORDERS INDUCED BY WATER AVOIDANCE STRESS IN RATS
Irritable bowel syndrome (IBS) is a chronic condition that affects the lower gastrointestinal tract. It affects the function and behavior of the intestine resulting in abdominal pain, flatulence, loose stools, frequent stools, feeling of being unable to completely empty bowel and nausea. Moringa oleifera, also commonly known as drumstick tree, is a highly valued plant with a wide range of medicina...
3892
1489
HPTLC QUANTIFICATION OF n-OCTACOSANOL IN TINOSPORA CORDIFOLIA MIERS STEMS OBTAINED FROM DIFFERENT GEOGRAPHICAL REGIONS
n-octacosanol is an normolipidemic aliphatic primary alcohol obtained from the plant Tinospora cordifolia Miers. In the present study, the plant stems were collected from five accessions namely Anniyalam, Chennai, Hassan, Vishakhapatnam and Bangalore between June and August. Later a simple HPTLC method has been established for determination of n-octacosanol in methanolic extracts of all these geog...
3891
1391
DIFFERENCE BETWEEN NATIVE AND MUTANT RHIZOBIUM ON GROWTH OF VIGNA MUNGO L.
The present study, carry out the use of plant growth promoting rhizobacteria, were used to improve the yield in crop. The Rhizobium strains isolated from legumes plant Mimosa pudica L and this strain was mutated by using UV radiation. The plant growth hormones were detected by native as well as mutant Rhizobium strains by paper chromatography techniques. The same strains use in conducted to green ...
3891
1688
CARBOHYDRATE METABOLISM AND THE STATE OF THE PRO-ANTIOXIDANT SYSTEM IN THE PANCREAS OF RATS WITH EXPERIMENTALLY INDUCED DIABETES AND THE RELEASE OF VANADIUM CITRATE
We investigated the effect of vanadium citrate in the amounts of 0.125, 0.5, and 2.0 µg/mL of water on the enzymatic activity of carbohydrate metabolism, antioxidant system, and the level of lipid peroxide oxidation products in the pancreas of rats with alloxan-induced diabetes. Diabetes was detected at a glucose level of 15.14 mmol/L by measuring glucose level in the blood collected from the tai...
3890
1477
ANTI ULCER ACTIVITY OF HELIOTRPIUM INDICUM LEAVES EXTRACT
The objective of present study is to evaluate the anti ulcer activity of ethanol extract of leaves of Heliotropium indicum. The ethanol extract of H. indicum was investigated for its anti ulcer activity against Aspirin plus pylorus ligation induced gastric ulcer in rats, HCl –Ethanol induced ulcer in mice and water immersion stress induced ulcer in rats. The antiulcer activity was assessed by de...
3889
1590