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GC-MS ANALYSIS OF BIOACTIVE COMPONENTS ON THE FRUIT EXTRACTS OF ARTOCARPUS HIRSUTUS LAM.: A POTENTIAL WILD EDIBLE PLANT
Wild fruits play a significant role in human nutrition, especially as sources of carbohydrates, proteins, vitamins, minerals, dietary fibers, and enormous medicinal potential. Local people in different parts of the country have learned to live on many wild edible fruits available around their localities. Artocarpus hirsutus Lam. is an important wild edible fruit plant belongs to the family Moracea...
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DEVELOPMENT OF HERBAL NIOSOMES FOR WOUND HEALING
Traditionally Psidum guajava has been used for the treatment of several kinds of disorders. The component quercetin a flavonoid that is present in the guava leaves, is responsible of having wound healing properties, so the aim and objective of the study was to Develop Herbal loaded Niosomes for the treatment of Wound Healing. To enhance the transport and efficacy of many materials through stratum ...
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STATINS IN POLYCYSTIC OVARY SYNDROME
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women. PCOS varies from a mild menstrual disorder to severe disturbance of reproductive and metabolic functions. Statins, 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors with intrinsic antioxidant properties, exert profound and broad-reaching effects on various types of tissues. By blocking an early step of th...
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ANTIMICROBIAL ACTIVITY OF EXACUM LAWII EXTRACTS AND VOLATILE OIL AGAINST OCULAR INFECTION
Exacum lawii is folklore medicinal herb, boiled with oil and used traditionally for ocular infection. The aim of the present study is to evaluate the in-vitro antibacterial and antifungal activity against ocular infection. Ethanolic extract, petroleum ether extract and volatile oil were extracted from Exacum lawii whole plant. Antibacterial activity and antifungal activity against strains causing ...
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A REVIEW ON ETHNOMEDICINAL PLANTS OF ASSAM (INDIA) USED IN THE TREATMENT OF DIABETES MELLITUS
Diabetes mellitus is one of the most prevalent metabolic disorders and has been a leading cause of death in the last few decades. Oral hypoglycaemic agents are mostly used in the treatment of diabetes, but the main drawback of these agents is that they have some unavoidable side effects. Nowadays, researchers are mainly focusing on unexposed medicinal plant species as an alternative source for the...
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THE EFFECT OF PSYCHIATRIC EDUCATION ON THE ATTITUDE OF MEDICAL STUDENTS OF GUILAN UNIVERSITY OF MEDICAL SCIENCES TOWARD PSYCHIATRY
Introduction: While many medical students have a special talent in psychiatry, attracting them to this specialty is a problem. The purpose of this study was to examine the impact of psychiatric education on the attitude of medical students on psychiatric patients. Method: In this observational study, 200 medical externs and interns were recruited. Before and after attending the 4-week psychiatry e...
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NANOEMULSION-BASED CAMPHOR OIL CARRYING IFOSFAMIDE: PREPARATION, CHARACTERIZATION, AND IN-VITRO EVALUATION IN CANCER CELLS
Formulating the essential oils with the chemotherapeutic agents in nanocarrier may develop a potent effect on the cancer cells. A nanoemulsion consisting of the camphor oil (CAM-NE) and Ifosfamide (IFO)-loaded in CAM-NE (CAM-IFO) were physically characterized by the zetasizer and evaluated for in-vitro antiproliferative activity against MCF-7 breast and HeLa cervical cancer cell lines. The cell gr...
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PRE-TRANSCRIPTIONAL GENE SILENCING TECHNIQUE FOR CONTROLLING SKIN CANCER
Familial cancers, which are in general incapable of exhibiting symptoms at the early onset period of the disease, can become fatal if left undiagnosed. Such cancers turn out to be a great threat through many generations in the long run. The remedial alternative to this is treatment at the genetic level which quite obviously points out to gene therapy. In this work, gene therapy proposed at the...
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DEVELOPMENT AND VALIDATION OF GC-MS METHOD FOR THE TRACE LEVEL DETERMINATION OF STRUCTURALLY ALERT ALKYL HALIDE IMPURITIES IN CILASTATIN SODIUM DRUG SUBSTANCE
A Simple and trace level-sensitive Gas chromatography with mass spectrometer (GCMS) method was developed, optimized and validated for the determination of seven potentially genotoxic impurities which are having structural alerts i.e., 1-Bromo-5-chloropentane (PGI-1), Ethyl-6-chloro-2-oxo hexanoate (PGI-2), Methyl-7-chloro-2-oxo hepta-noate (PGI-3), Ethyl-7-chloro-2-oxo heptanoate (PGI-4), Ethyl-7-...
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DESIGN, SYNTHESIS AND CYTOTOXIC ACTIVITY OF SOME NOVEL FLAVONES
A series of flavones (5-15) weresynthesized from resorcinolvia Baker-Venkataraman transformation, characterized and evaluated for their cytotoxicity against human cervical cell line (HeLa) by MTT assay method. The result of preliminary MTT cytotoxicity studies shown that the compounds 5, 9 and 10 were found to be most potent against HeLa cells; IC50 values were of 0.22, 0.88 and 1.26 µM respect...
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