Most Popular
ANALYTICAL QUALITY BY DESIGN APPROACH IN RP-HPLC METHOD DEVELOPMENT FOR THE ASSAY OF PITAVASTATIN IN TABLET DOSAGE FORM
Chromatographic method was developed according to Quality by Design (QbD) approach as per ICH Q8 (R2) guidelines for estimation of pitavastatin in pharmaceutical dosage form. By considering the current regulatory requirement for an analytical method development, a reversed phase high performance liquid chromatographic method for routine analysis of Pitavastatin has been optimized using analytical ...
3532
1686
EFFECTS OF GREEN TEA INFUSION AND EPICATECHIN ON DOXORUBICIN-INDUCED RENOCARDIOTOXICITY IN MALE ALBINO RATS
This study aims to assess the preventive effects of green tea infusion and epicatechin on doxorubicin (Dox)-induced kidney and heart injuries and oxidative stress in male Wistar rats. The male Wistar rats administered Dox at an intraperitoneal dose of 4 mg/kg body weight (b.w.)/ week were orally treated with green tea infusion (200 mg/kg b.w.) and epicatechin (25 mg/kg b.w.) every other day for 6 ...
3532
1367
POSTNATAL DEVELOPMENT OF STOMACH IN SWISS MICE INDUCED BY LEAD ACETATE
Histopathological changes in developing stomach caused by lead acetate exposure at different days of the postnatal development were investigated in Swiss mice. In this study, pregnant Swiss mice were exposed to 533 mg/kg BW of lead acetate from 10th day of gestation to 21st day of lactation. The pups of exposed groups were sacrificed at 1, 7, 14 and 21 day of lactation period, and the effects of l...
3531
1811
HEMAGGLUTININ PROTEIN 35.7 kDA ACTS AS AN ADHESION MOLECULE IN THE OUTER MEMBRANE PROTEIN (OMP) OF SHIGELLA DYSENTERIAE
Shigellosis becomes a major health problem of developing countries. It is caused by Shigella spp. Shigella dysenteriae causes the most severe; prolonged and fatal Shigellosis by its ability in producing Shigatoxin (Stx). Unfortunately, there has not been any effective vaccine available in worldwide and using antibiotic is no longer effective. Adhesion molecule of bacteria can be used as component ...
3531
1490
PHYTOCHEMICAL INVESTIGATION AND BIOLOGICAL ASSESSMENT OF 12-HYDROXY-OCTADEC-CIS-9-ENOIC ACID ISOLATED FROM SWIETENIA HUMILIS ZUCC. SEED OIL
The genus Swietenia belongs to Meliaceae family which consists of 37 genera and about 300 species which is found in most of the parts of India. In present investigation we made an efficient effort to extract ricinoleic acid from the seed oil of Swietenia humilis, Zucc. They are used in medicine folklore to cure various diseases in Mexico, Africa and India. Physicochemical properties of Swietenia h...
3529
1716
ENCAPSULATION OF REPAGLINIDE INTO EUDRAGIT RS MICROSPHERES AND MODULATION OF THEIR RELEASE CHARACTERISTICS BY USE OF SURFACTANTS
Microspheres containing Repaglinide was prepared by emulsion solvent evaporation technique using two types of surfactants Tween 80 (polysorbate 80) and Span 80 (Sorbitanmonooleate 80). The effect of change in the type and surfactant amount on the size and drug release from the microspheres was investigated. The release of Repaglinide from the microspheres exhibit diffusional characteristics and cl...
3528
1542
AN INVESTIGATION OF IN-VITRO RELEASE OF RABEPRAZOLE SODIUM FROM PULSATILE RELEASE TABLETS CONTAINING HPMC-EC BLEND AS TIME LAGGED PRESS COATING
To develop new pulsatile release tablets of Rabeprazole sodium (RS), that can suppress drug release in stomach and release the drug rapidly after a predetermined lag time for about 4 h in intestine, a multiple unit dosage forms was designed that contain, drug-containing core, a coating to achieve time lag in drug release and an outermost acid resistant enteric coating. Time lagged press coating wa...
3528
1768
BOMBAX CEIBA: A PLANT OF THERAPEUTIC POTENTIAL
Medicinal plants have been utilized to treat a wide range of illnesses throughout human history. Plants are able to produce a wide variety of secondary metabolites, which are chemical substances that assist them defend against predators. The plants are significant for their therapeutic significance because of these organic ingredients, which also have various biological actions. Red silk cotton tr...
3528
1415
ESTIMATION OF PROTEINS IN PLANTS OF FORENSIC SIGNIFICANCE (RICINUS COMMUNIS AND CANNABIS SATIVA) BY UV-SPECTROPHOTOMETRY AND GEL ELECTROPHORESIS METHOD
Proteins play a significant role in living beings. In animals, where proteins are involved in the body built, the formation of tissues, organs, etc., in plants, proteins regulate the respiration, photosynthesis, growth, and reproduction. There are some proteins which are specific to the plant or a particular species of plant. Proteomics is a multidisciplinary branch of science that deals with the ...
3527
1497
EVALUATION OF RENAL EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF PORTULACA OLERACEA (WHOLE PLANT) IN ALLOXAN INDUCED DIABETIC RATS
Herbal plants are effective in the treatment of various diseases. More or less they are unscientifically and improperly used. These plants deserve detailed studies in the light of modern medicine. Having detailed investigation and documentation  of herbal plants used in local  health traditions  and after that doing pharmacological evaluation of these plants andÂ...
3526
1400