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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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32.

PRELIMINARY PHYTOCHEMICAL INVESTIGATION, IN-VITRO ANTIOXIDANT, IN-VITRO α-AMYLASE INHIBITION, IN-VITRO AND IN-VIVO ANTICATARACT ACTIVITY OF ETHYLACETATE ROOT EXTRACT OF ABUTILON INDICUM

The present study aims to evaluate the in-vitro antioxidant, in-vitro α-amylase inhibition, in-vitro and in-vivo anti-cataract potential of ethyl acetate root extract of Abutilon indicum. Antidiabetic activity was evaluated against alpha-amylase by spectrophotometric assays. DPPH determined antioxidant activity, Reducing power assay, Phosphomolybdenum antioxidant assay, Nitric oxide-scavenging ac...

G. V. N. Kiranmayi *, P. Sirisha and R. Sanjana

Faculty of Pharmacy, Dr. M. G. R. Educational and Research Institute, Deemed to be University, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.14(2).827-37

827-837

3160

998

11.

PURIFICATION AND CHARACTERIZATION OF ANTI-HYPERGLYCEMIC BIOACTIVE MOLECULE FROM COSTUS PICTUS D. DON

Costus pictus D. Don., commonly known as the ‘Insulin plant’ is being used as a natural remedy to treat diabetes mellitus. The present study is focused to identify the chemical constituent responsible for the anti-diabetic activity of Costus pictus. The methanol extract was prepared from the fresh leaves of Costus pictus and washed with water to remove excess oxalic acid content present to get...

M. Benny *, B. Antony, A. P. A. Aravind, N. K. Gupta, B. Joseph and I. R. Benny

Research and Development Laboratory, Arjuna Natural Private Ltd., Erumathala, Aluva, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2075-81

2075-2081

3158

1434

30.

INDOLE 1,2,3,4-TETRAHYDROPYRIMIDINONE: SYNTHESIS, CHARACTERIZATION AND IT’S BIOLOGICAL APPLICATIONS

The present research work involves the use of exclusively and commercially available indole-3-carbaldehyde as a starting material to synthesize novel pyrimidine analogues. The synthesis of series of indole and pyrimidine containing N-substituted-4-(1H-indol-3-yl)-6-methyl-2-oxo-1, 2, 3, 4-tetrahydro-pyrimidine-5-carbohydrazide U(1-10) has been done by using principle of Biginelli condensation reac...

G. S. Mhaske *, R. H. Khiste, S. A. Shinde and S. A. Jadhav

Department of Pharmaceutical Chemistry, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(2).963-72

963-972

3157

1790

48.

A STUDY ON IDENTIFICATION OF RISK FACTORS OF POLYCYSTIC OVARIAN SYNDROME BY CONDUCTING SURVEY AND MINIMIZING THEM THROUGH PATIENT COUNSELING AND ITS IMPACT ON QUALITY OF LIFE

Background: Polycystic ovarian syndrome (PCOS) is a very common Endocrine Disorder encountered in women in which there is an imbalance of female sex hormones. It is associated with problems such as menstrual irregularities, Hirsutism, Obesity, Insulin resistance, acne, and in later life infertility with Diabetes mellitus and uterine cancer. Objectives: 1. Identify the subjects who are at risk for ...

S. Budharam, S. Veeramreddy, D. S. Goluguri and A. Rajani *

Department of Pharmacy Practice, MNR College of Pharmacy, Sangareddy, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.11(11).5747-52

5747-5752

3156

1686

32.

IN-SILICO SCREENING OF FLAVONOLS AGAINST BRUGIA MALAYI ASPARAGINYL tRNA SYNTHETASE

Lymphatic Filariasis is one of the most abandoned tropical diseases caused by the parasite, Brugia malayi. The existing conventional drugs act generally on the larval stages of the parasite. The enzyme asparaginyl tRNA synthetase is an excellent molecular target as it plays a crucial role in protein synthesis. Evidences based on the literature presented clues to discover the flavonoids as potentia...

P. A. Kamble * and S. J. Wadher

School of Pharmacy, Swami Ramanand Teerth Marathwada University, Nanded, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(9).3858-62

3858-3862

3154

1293

59.

RELATIONSHIP BETWEEN SMOKING AND HISTOLOGY OF LUNG CANCER IN MALAPPURAM DISTRICT OF KERALA, SOUTH INDIA

Background: Lung Cancer is the commonly diagnosed neoplasm in males in India. The main histological types of lung cancer are squamous cell carcinoma, adenocarcinoma, small cell carcinoma and large cell carcinoma. However, histological types may vary with the changes in geographical region, smoking status and other social factors. This study aimed to find out the relationship of smoking and histolo...

C. Muhas, P. R. A. V. Kumar *, P. Seenivasan and D. Raja

Department of Pharmacology, JSS Academy of Higher Education and Research, JSS College of Pharmacy, Ooty, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.9(12).5490-95

5490-5495

3152

1240

16.

ACUTE, SUB-ACUTE AND ANTIOXIDANT ACTIVITIES OF ARTHROPHYTUM SCOPARIUM AERIAL PARTS

This study aims to evaluate the in-vitro and in-vivo antioxidant activity of different extracts prepared from the aerial parts of Arthrophytum scoparium. Polyphenols flavonoids and tannins contents were determined. The acute toxicity of ASE was carried out based on OECD during two weeks to ascertain the LD50. In sub-acute toxicity, a 100, 200 and 400 mg/kg/day extract was orally administrated for ...

S. M. Kaddour *, F. Zerargui, L. Arrar and A. Baghiani

Laboratory of Applied Biochemistry, Department of Biochemistry, Faculty of Nature and Life Sciences, University Ferhat Abbas, Setif, Algeria.

DOI: 10.13040/IJPSR.0975-8232.10(9).4167-75

4167-4175

3152

1567

34.

DESIGN, DEVELOPMENT AND EVALUATION OF POLYHERBAL TABLET OF TWO ANTI-ULCER LEAVES

Aim: The present study was to develop and evaluate antiulcer polyherbal tablet as designing of oral herbal formulation. The methanolic extracts of Abrus precatorius (MEAP) and Cordia wallichi (MECW) leaves were used in different concentrations in the formulations. Materials and Method: The current exploration was to design a gastro-retentive drug delivery system of MEAP and MECW using swelling pol...

R. Sengupta * and N. M. Zaveri

Girijananda Chowdhury Institute of Pharmaceutical Sciences, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.12(6).3291-97

3291-3297

3152

1456

4.

AN UPDATED REVIEW ON THE THERAPEUTIC POTENTIAL OF PRUNUS ARMENIACA

Excessive  drug  therapy,  environmental  pollutants,  hepatic  cancer  and  alcoholic  intoxicants  are  the  main  causes  of  liver  disorders. The hepatic disorders/toxicity can occur by several mechanisms like cytochrome P450 activation, lipid peroxidation, induction of nitric acid synthase, mitochondrial dysfunction, activation of pro-inflammatory mediators and bile acid-indu...

Varsha Raj *, Prevesh Kumar, Munish Mani and Navneet Verma

Department of Pharmacy, I. F. T. M. University, Moradabad, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.12(9).4600-15

4600-4615

3152

2148

01.

A REVIEW ON CARBON DOTS PRODUCED FROM BIOMASS WASTE-ITS DEVELOPMENT AND BIO-APPLICATIONS

Carbon nanomaterials belong to the carbonaceous family of less than 10 nm in size called Carbon dots (C-dots); the latest class of engineered nanoparticles has recently gained popularity for their unique characteristic features, such due to their low toxicity and miniature size, it can penetrate cells easily, thus becoming highly biocompatible. The advancement of science and its collaboration with...

Paramita Debnath, Debargha Dutta and Bhaskar Choudhury *

Guru Nanak Institute of Pharmaceutical Science and Technology, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.14(1) 01-12

01-12

3152

1890