Most Popular
ANTI-NEOPLASTIC TRANSDERMAL PATCH: A NOVEL APPROACH IN BREAST CANCER THERAPY
Background: In the present investigation Antineoplastic loaded transdermal patch was formulated using Liposomes, eudragit-RL, hydroxypropyl methyl cellulose K-50, and ethyl cellulose. Materials and Methods: Liposomes were formulated by solvent evaporation method using poly (sebacic acid-co-ricinoleic acid) in varying ratios and evaluated for particle size, drug loading, entrapment efficiency, tr...
2726
1464
DNA SEQUENCING, MUTATIONAL ANALYSIS OF NOVEL COMT GENE VARIANTS AND ITS PATHOGENICITY IN SCHIZOPHRENIA PATIENTS: ACROSS-SECTIONAL STUDY FROM TUMKUR DISTRICT OF SOUTH KARNATAKA
Introduction: Schizophrenia is a multi-factorial neuropsychiatric disorder, influenced by environmental and genetic factors. The catechol-O-methyltransferase (COMT) gene is a crucial for the metabolism of dopamine. It has been thoroughly investigated for its potential role in SCZ. At the same time; several variants in the COMT gene have been reported in diverse populations in South Karnataka but r...
2725
12742
GC-MS INVESTIGATION OF PHYTOCOMPONENTS PRESENT IN ETHANOLIC EXTRACT OF PLANT ICHNOCARPUS FRUTESCENS (L.) W. T. AITON AERIAL PART
Ichnocarpus frutescens (Apocynaceae) generally renowned as Kali Sariva in Sanskrit, Krishna Sariva in Hindi which is a large, evergreen, red woody climber, native to India, Java, China, Southeast Asia, Ceylon, Northern Australia and found ascending to an altitude of 4,000 ft. Different tribes of India are used this plant as a substitute of Indian Sarsaparilla (Hemidesmus indicus). It has been used...
2724
1690
PHARMACOGNOSTICAL EVALUATION AND PRELIMINARY PHYTOCHEMICAL ANALYSIS OF DIFFERENT PARTS OF LAGERSTROEMIA SPECIOSA
The present study aimed to determine the pharmacognostical evaluation and phytochemical analysis of the plant part of Lagersreomia speciosa. In this study, a macroscopical, microscopical evaluation was done. Various quantitative parameters such as total ash, acid insoluble ash, water-soluble ash sulphated ash, extractive value with various solvent were done. In the preliminary phytochemical analys...
2724
1666
HAEMOTOXICITY OF LEAD (Pb) ON THE BLOOD PARAMETERS OF FRESH WATER TELEOST HETEROPNEUSTES FOSSILIS (BLOCH)
Blood parameters are important indicators for assessing the health status of living organisms subject to changing environment. Blood parameters (Hb%, TEC, TLC, ESR, PCV, MCH, and MCV) of Heteropneustes fossilis exposed to lead were investigated at different time intervals. Acclimatized specimens were divided into four groups: Group-A (Control), Group-B (2.25 ppm), Group-C (2.65 ppm), Group-D (2.85...
2722
1193
FORMULATION AND EVALUATION OF BILAYER FLOATING TABLETS OF ATORVASTATIN AND CAPTOPRIL
The aim of the present research work was to develop a bilayer floating dosage form of immediate-release Atorvastatin (ATR) and sustained release Captopril (CPT) in matrix form for the treatment of hyperlipidaemia and hypertension to reduce multiple dosing frequencies and enhance patient compliance. ATR belongs to the BCS Class II category having poor aqueous solubility, which was enhanced by using...
2722
1383
USAGE ASSESSMENT OF COMPLEMENTARY AND ALTERNATIVE MEDICINE IN SAUDI DIABETIC PATIENTS
Complementary and alternative medicines (CAMs), particularly herbal medicines (HMs), are popular with diabetic patients and are often used alongside conventional treatments. In such cases, patients usually do not advise their doctor or any other healthcare professional, so inappropriate use and potential interactions between CAM therapies and conventional treatments are serious concerns. This stud...
2720
1248
CLINICAL FEATURES, TREATMENT APPROACHES AND PROMISING CONTRIBUTIONS OF NANOMEDICINES TOWARDS COVID-19
The World Health Organization (WHO) declared COVID -19 a pandemic on March 11 2020. As of today, there have been 122 million COVID -19-update cases worldwide, and the counting goes on. Unfortunately, strategic measures such as total lockdown, social and self-isolation, and gradual lifting of some of these restrictions both pose economic, social, and psychological distress and are thought to hav...
2720
1165
EVALUATION OF IN-VIVO ANALGESIC ACTIVITY OF ARGYREIA CYMOSA (ROXB.) SWEET
The current research was accomplished to assess the analgesic activity of Argyreia cymosa (A. cymosa) methanolic extracts (MEAC) at 200 and 400 mg/kg. The entire herb was extracted with the methanol (MEAC). Acute oral toxicity of the extract was according to OECD-423 recommendations. Analgesic activity was explored by utilizing hot plate, tail immersion and acetic acid-evoked writhing models. In a...
2717
1297
AN OLD ADAGE MANAGEMENT PERSPECTIVE FOR DANDRUFF
Dandruff is a well-known and global consumer problem, characterized by flaking and scaling of the scalp, with itching and irritation. Although it is not a life-threatening disease, but it is directly related to individual self-esteem, confidence, and beauty. Approximately half of the population is suffering from dandruff and expending around billions of dollars, including hospital services and cou...
2715
1953