Most Popular
SCREENING SELECTED SPECIES OF GOMPHOSTEMMA WALL. EX BENTH. FROM WESTERN GHATS FOR ANTI-INFLAMMATORY ACTIVITY
Gomphostemma Wall. ex Benth. belongs to the family Lamiaceae. The present study evaluated selected species of Gomphostemma endemic to the Western Ghats for their anti-inflammatory property. Traditionally, many species of Gomphostemma are used to treat malarial fever and inflammations caused by insect stings. Methanol extracts of Gomphostemma heyneanum var. heyneanum, G. heyneanum var. rottleri and...
2703
1292
CHEMOMETRIC APPROACH FOR RP-HPLC DETERMINATION OF DRONEDARONE USING RESPONSE SURFACE METHODOLOGY
The present study depicts the assessment of class III antiarrhythmic drug dronedarone in its drug substance and drug product. Response surface randomized central composite quadratic design has been employed for the optimization of method parameters using reverse-phase high-performance liquid chromatography (RP-HPLC) on Kromasil C18 250 × 4.6 mm, 5 µ with UV detection at 289 nm. The ranges of the...
2703
1203
ASSESSMENT OF OXIDATIVE STRESS MARKERS IN CATARACT
Introduction: In spite of the progress made in surgical techniques for cataract removal all over the world during last ten years; still age related cataract remains the leading cause of visual impairment. The etiology of cataract is multi-factorial and oxidative damage is one of the causes. Aim: To estimate oxidative stress by markers like enzymatic antioxidant Superoxide Dismutase (SOD) and lipid...
2700
1295
COMPREHENSIVE STUDY OF VANDA ROXBURGHII: TRADITIONAL USES, PHYTOCHEMISTRY, AND PHARMACOLOGICAL SIGNIFICANCE
In order to discover new treatments for a wide range of ailments, ethnopharmacological research has investigated different leads from plants. In nature, the Orchidaceae family's Vanda roxburghii is found in Bangladesh and India. As a remedy for dyspepsia, bronchitis, and inflammations, as well as for rheumatoid arthritis and bronchitis, various portions of the plant are employed. A number of the p...
2700
1382
BLACK TEA THEAFLAVINS: A REVIEW OF THE EVIDENCE
Tea brewed from the plant Camellia sinensis is the second most popular beverage consumed worldwide after water. The first two leaves and the leaf bud are mainly used for commercial tea production, and depending on the variation of processing techniques, it is primarily categorized into -white tea, green tea, oolong tea, and black tea. Different varieties of tea are known for their contribution in ...
2699
1330
DESIGN AND EVALUATION OF CIPROFLOXACIN FLOATING TABLETS USING THERMAL SINTERING TECHNIQUE
The main of this study was production of floating tablets to maintain the drug stay in its absorption area. Ciprofloxacin is better absorbed in the stomach because of this reason floating matrix tablet was prepared using novel sintering technique with sodium bicarbonate as gas generating agent and a polymer eudragit robust formulation was decided on the basis of floating time and in-vitro drug rel...
2699
1488
GC-MS AND FT-IR ANALYSIS OF METHANOL FRUIT EXTRACT OF FICUS RACEMOSA AND FICUS AURICULATA
The fruits of the plant Ficus racemosa and Ficus auriculata are consumed as a wild edible fruit and have also been used extensively in traditional medicine to treat various illnesses ranging from diarrhea, dysentery, jaundice to diabetes, piles, asthma, and urinary diseases. Gas Chromatography-Mass Spectro-metry (GC-MS) analysis of methanol extract of the fruits was carried out to identify the pos...
2699
1597
THE POTENTIAL ROLE OF FLAVONOIDS IN THE CONTROL OF OXIDATIVE STRESS FOR TYPE II DIABETES
Introduction: Antioxidant properties of flavonoids may guard against oxidative damage to cells, DNA, or lipids. The ample literature about flavonoids can affirm the structural and pharmacological cherishing of this class of phytochemicals. The presence of aromatic rings in the flavonoid molecule consent the receiving and donation of electrons from free radical species, which abets to curb the free...
2697
1179
EVALUATING THE EFFECTS OF COMMIPHORA MOLMOL (MYRRH) AGAINST OXIDATIVE DNA DAMAGE IN HUMAN LYMPHOCYTES
Oxidative stress is a condition that might predispose individuals to diseases, including cancer. The 8- hydroxydeoxyguanosine (8-OHdG) is an index that reflects DNA damage caused by oxidative stress in the body. In this study, Commiphora molmol (Myrrh) (C. molmol) (Myrrh) that belongs to the family Burseraceae were investigated for its potential favorable properties to blunt DNA damage induced by ...
2695
1331
LAMININ DERIVED PEPTIDES: A PROMISING AND TISSUE-SPECIFIC APPROACH
Tissue specificity is the essential need of the hour to cut down clinical abnormalities. Allowing desired drug concentration to reach the target site is the current trend of the drug delivery system. Laminin is an active component of the basal lamina and present in most cells and organs has shown great utility in this case. It is a heterotrimeric glycoprotein containing an α-chain, a β-chain, an...
2694
1514