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EVIDENCE BASED ANTI-DEMENTING ACTIVITY OF SARASWATA GHRITA “A NOOTROPIC COMPOUND FROM AYURVEDA
Life expectancy is increasing as a result of advancement in medical science and the availability of better healthcare services. As the risk of dementia increases with increasing age, the number of persons with dementia in the general population is also rising. Alzheimer’s disease is the most common form of dementia, accounting for approximately 70%...
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EVALUATION OF ANTIMICROBIAL ACTIVITY OF DIFFERENT HERBAL PLANT EXTRACTS
This work has been undertaken to study the antimicrobial efficiency of Hexane, Ethyl acetate, Ethanolic extracts of herbal plants (Anthocephalus cadamba, Allium sativum, Origanum vulgare, Ocimum sanctum) against human pathogens like Staphylococcus aureus (MTCC-3160), Escherichia coli (MTCC-1652) and fungi Aspergillus niger (MTCC-282) by using agar well diffusion method. All the plants showed signi...
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SELF‑MEDICATION AMONG UNDERGRADUATE MEDICAL STUDENTS IN TWO UNIVERSITIES IN SYRIA
Self-medication is the selection and use of medicines by individuals to treat self-recognized illnesses or symptoms. Studies performed on self-medication reveal that it is a fairly common practice, especially in economically deprived communities. This Descriptive cross sectional study assessed the self‑medication issue among medical students of Aleppo Government University (AGU) and Al-Andalus P...
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DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR THE ESTIMATION OF DAPAGLIFLOZIN IN API
An accurate, precise, specific and rapid RP-HPLC method was developed and subsequently validated for the determination of Dapagliflogin in API. Better separation of the drug was achieved on BDS column (250×4.5mm, 5µ) with a mobile phase consisting of a mixture of ortho phosphoric acid and acetonitrile (45:55 v/v) at a flow rate of 1ml/min, with detection at 245nm using Photo Diode Array (PDA) de...
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A REVIEW ON THE POTENTIAL USE OF BLACK GINGER FROM EASTERN INDIA
Kaempferia parviflora Wall. Ex Baker is commonly known as ‘black ginger’ which belongs to the family Zingiberaceae. These are mostly found in the subtropical and tropical areas of Asia. It bears various pharmacological properties such as anticancerous, anti-allergic, anti-inflammatory, antioxidant and antimicrobial. Upon the reports we reviewed the plant aromatic rhizomes contained important p...
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A NOVEL HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF CHLORPHENIRAMINE MALEATE AND DEXTROMETHORPHAN IN BULK AND PHARMACEUTICAL FORMULATION
Chlorpheniramine maleate and Dextromethorphan are used in treatment of cough caused by allergies and the common cold by decreasing intra ocular pressure. The present study was designed to develop and validate a simple, sensitive, precise and accurate reverse phase high performance liquid chromatographic (HPLC) method for simultaneous determination of Chlorpheniramine maleate and Dextromethorphan i...
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FORMULATION AND CHARACTERIZATION OF NIMODIPINE NANOEMULSION AS AMPOULE FOR ORAL ROUTE
The aim of this study was to develop oil in water nanoemulsion of nimodipine intended for oral use. Nimodipine is a calcium channel blocker that has poor oral bioavailability (3-30%) due to its low solubility and first- pass metabolism. So, nanoemulsion of nimodipine increase its solubility and enhance its oral bioavailability. Pseudo -ternary phase diagrams were made by using aqueous titration me...
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STUDY OF ANTHELMINTIC AND INSECTICIDAL ACTIVITIES OF DIFFERENT EXTRACTS OF KAEMPFERIA GALANGA
Kaempferia galanga has profound implications in the treatment of nematocide, larvicide, abdominal discomfort, cholera, various inflammatory diseases and many more. It is a potential candidate in terms of evaluating its medicinal activities. Therefore, the present study was conducted to evaluate anthelmintic and insecticidal activities of different extracts of the rhizome of Kaempferia galanga. For...
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STEM CELLS IN REGENERATIVE ENDODONTICS
Endodontic treatment is helpful in saving millions of teeth each year, but at present the focus has shifted towards regenerative approaches as an ideal form of therapy to treat diseased or necrotic pulp tissues. Regeneration of lost tissues has been known for a very long time, but their use in dentistry is gaining momentum. The growing understanding of biological regeneration has permitted the use...
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FORMULATION AND EVALUATION OF MUCOADHESIVE BUCCAL TABLETS OF PROPRANOLOL PREPARED USING NATURAL POLYMER
Propranolol is beta-blocker and it is widely used in the management of hypertension. Propranolol is used to treat tremors angina, hypertension, heart rhythm disorder and other heart or circulatory conditions. The mucoadhesive buccal tablets of propranolol were papered by wet granulation method using natural polymer like Vigna mungo powder. The compatibility studies of drug and excipient were perfo...
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