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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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38.

ANTI-INFLAMMATORY ACTIVITY OF METHANOLIC EXTRACT OF BRASSICA JUNCEA SEED ON CARRAGEENAN INDUCED PAW EDEMA IN RATS

Inflammation is a primary physiological defense mechanism that helps the body to protect itself from infection, toxic chemicals, or other noxious stimuli. The methanolic seeds extract of Brassica juncea was evaluated for its anti-inflammatory activity, in-vivo methods. Anti-inflammatory drugs with low toxicity and higher therapeutic values. It is a defensive mechanism of the body to remove the inj...

Y. S. Chouhan *, H. C. Kataria and C. S. Gosawmi

Department of Chemistry, Govt. Geetanjali Girls P.G. College, Barkattulla University, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.5(9).3849-51

3849-3851

8998

2708

7.

CANCER CAUSES AND TREATMENTS

Cancer is a genetic disorder that results from genetic or epigenetic alterations in the somatic cells and has abnormal cell growth which may be spread to other body parts. In 2018, 18 million cancer was recorded globally in which 9.5 million cancer cases in men, 8.5 million cases in women, and 9.6 deaths were also recorded in the same year. The most spreading cancer globally is prostate, breast, l...

A. Saini, M. Kumar, S. Bhatt, V. Saini and A. Malik *

Department of Pharmaceutics, M. M. College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.11(7).3109-22

3109-3122

8997

4126

46.

PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF METHANOLIC EXTRACT OF DATURA STRAMONIUM SEEDS

The present study was concerned with phytochemical screening of methanolic extract of Datura stramonium seeds and its antioxidant and antimicrobial activities. The methanolic extract was prepared by using Soxhlet apparatus. The result of phytochemical screening of methanolic extract of Datura stramonium seeds shows presence of various phytoconstituents like alkaloids, flavonoids, amino acids, tann...

Samier A. Waza , Prashant Anthony and Sikander Dar *

Department of Chemistry, Sam Higginbottom Institute of Agriculture, Technology and Sciences (Formerly AAI-DU), Allahabad, U.P. India

DOI: 10.13040/IJPSR.0975-8232.6(7).3021-26

3021-26

8976

2916

18.

MODULATION OF TUMOUR NECROSIS FACTOR Α ATTENUATES NALOXONE-PRECIPITATED OPIOID WITHDRAWAL SYNDROME

The present study has been designed to investigate the effect of modulation of tumour necrosis α (TNF-α) on naloxone induced opioid withdrawal syndrome. Chronic morphine (5mg/kg,i.p) administration followed by a single injection of naloxone (8mg/kg, i.p)  was used to precipitate opioid withdrawal syndrome in mice. Behavioral observations were made immediately after naloxone treatment. Withdrawa...

Gurpreet Bawa* and Amarjot Kaur Grewal

Rayat and Bahra Institute of Pharmacy, Sahauran, Kharar, District Mohali - 140104, Punjab, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(8).3216-25

3216-3225

8962

1514

1.

UPBRINGING OF CHILDREN AND ROLE OF UNANI MEDICINE IN CHILD HEALTH CARE: A REVIEW

Infancy is the most important period of human life, because a infant grows up to be a healthy teen and adult, parents should have to take precautions seriously so as to impart a healthy life  to their child, since the immunity of children is not so strong as that of adults so they are prone to diseases and illnesses, the medicine used in conventional system of medicine for such pediatrics ailment...

Azizur Rahman and S. Javed Ali *

Department of Medicine, National Institute of Unani Medicine, Bangalore - 91 India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(5).1820-25

1820-1825

8962

2545

12.

ANTIOXIDANT AND HAEMATOPROTECTIVE ACTIVITY OF THE SARACA INDICA STEM BARK

Present study was designed to evaluate the antioxidant and hematoprotective activity of methanolic extract of saraca indica bark. Antioxidants and hematoprotective effect of saraca indica bark may be due to its polyphenolic compounds. Polyphenols act as reducing agents via scavenging of free radicals and chelation of transition metals. The hematoprotective activity of Saraca indica was studied in ...

C. K. Dubey, A. K. Meena, V. Mishra, P. Singh, F.W. Bansode and R. K. Singh

Division of Toxicology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.6(4).1430-37

1430-37

8957

2375

43.

STANDARDIZATION OF ASHWAGANDHA GHRITA: A HERBAL GHEE BASED AYURVEDIC MEDICINAL PREPARATION

Background: The WHO assembly in number of resolutions has emphasized the need to ensure quality control of medicinal plant products by using modern techniques and applying suitable standards. Since Ayurvedic medicines come under the purview of Drugs and Cosmetics Act, there is increased general awareness about the necessity for developing standards for the purpose of quality control by the manufac...

Deepthi Viswaroopan* Arun Raj GR and Shailaja U

Department of Kaumarabhritya, SDM College of Ayurveda and Hospital, Hassan - 573201, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.7(2).819-23

819-23

8940

2979

10.

ROLE OF ANTIOXIDANTS IN ORAL MEDICINE

The realization that reactive oxygen species and oxidative stress play an important role in the etiology and progression of major human degenerative diseases has triggered enormous and worldwide interest in endogenous and exogenous antioxidants. The 1990’s have seen the explosion of interest in antioxidants. The article reviews free radical chemistry, antioxidant systems & their role in huma...

Sumit Bhateja

Department of Oral Medicine Diagnosis & Radiology, Dr. DY Patil Dental College & Hospital, Pune, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(7).1971-75

1971-1975

8938

2673

19.

PHARMACOKINETIC DERIVATION OF RATES AND ORDERS OF REACTIONS IN MULTI-COMPARTMENT MODEL USING MATLAB

Pharmacokinetic modeling is the representation of the logarithmic mathematical equations in order to measure the physiologic response of the body to the drug. Absorption, distribution, metabolism and excretion follow drug kinetic principles according to specific reaction mechanisms in which concentration of the drug may either be dependent or independent of drug-body interactions. Michaelis-Menten...

Z. M. Llarena

Gokongwei College of Engineering, De La Salle University Manila Manila, Philippines.

DOI: 10.13040/IJPSR.0975-8232.7(11).4456-60

4456-60

8938

2196

49.

MEASURING THE EFFECT OF DIFFERENT PARAMETERS ON THE CATALYTIC ACTIVITY OF IMMOBILIZED β-GALATOSIDASE FROM YEAST

Background: Enzyme catalysis is intermediate between homogeneous and heterogeneous catalysis. In general, it is similar to inorganic heterogeneous catalysis and sometimes it is called micro heterogeneous catalysis. Efficient enzyme catalysis depends on high specific nature of enzyme, pH, temperature, optimum temperature, colloidal nature, activator or co-enzyme, inhibitors or poisons. Immobilized ...

Sandhya Hora*, Manoj Gupta and Mamta Gupta

Central Research Laboratory, Department of Biochemistry, Shri Ram Murti Samarak-Institute of Medical Sciences, Bareilly-243202, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(12).4903-08

4903-4908

8931

1824