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CLINICAL PHARMACIST INTERVENTIONS IN DRUG THERAPY IN PATIENTS WITH DIABETES MELLITUS AND HYPERTENSION IN A UNIVERSITY TEACHING HOSPITAL
Introduction: Drug related problems occur commonly in patients who often receive polypharmacy with multiple co-morbid conditions. This constitutes a major health problem because of their negative consequences with increased morbidity and mortality. Aims and Objectives: The aim of the study was to assess the impact of clinical pharmacist interventions in drug therapy in hospitalized diabetes mellit...
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DEVELOPMENT AND BIOEQUIVALENCE STUDY OF OLANZAPINE 10mg TABLETS
Generic drugs are lower-cost versions of patent-expired original brand-name medications. According to guidelines of regulatory agencies of the Canada, US and European Union, a generic drug must be “identical, or bioequivalent to a brand name drug in dosage form, safety, strength, route of administration, quality, performance characteristics and intended use”. Bioequivalence is decreed when the...
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QUANTITATIVE DETERMINATION OF ETODOLAC BY UV SPECTROPHTOMETRIC METHOD IN BULK DRUG AND COMMERCIAL FORMULATIONS
The rapid and sensitive UV spectrophotometric method was described for the determination of etodolac, non-steroidal anti-inflammatory drugs. The type of solvent, the range of wavelength and the range of concentration were chosen in order to optimize the conditions. The developed and validated method was successfully applied to the analysis of etodolac without derivatization with any compound in co...
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BACTERIAL DIARRHOEA: A COMPREHENSIVE REVIEW
Infective diarrhoea is a common cause of malnutrition in children <5 years of age. The aetiological agents may be bacteria, viruses or parasites. The bacterial agents cause diarrhoea by either secretion of toxins which act on the small intestine to cause outpouring of fluids into the lumen as seen in Vibrio cholerae, enterotoxigenic Escherichia coli, Clostridium perfringens, Staphylococcus aure...
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A PEDICULICIDAL ACTIVITY OF CLOVE OIL
The humans head lice are a nuisance for millions of people worldwide with high prevalence in children. Head lice have been treated by methods that include the physical removal of lice, various domestic treatments and conventional insecticides. None of these methods render complete protection and there is clear evidence for the evolution of resistance and cross-resistance to conventional insecticid...
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ISOLATION AND CHARACTERIZATION OF MICROBES PRODUCING BACTERIOCIN FROM CURD, RAW MILK AND SOIL AND ITS PRESERVATIVE EFFECTS
Bacteriocins are proteinaceous substance produced by bacteria to inhibit the growth of similar or closely related bacterial strains. They are typically considered to be narrow spectrum antibiotics produced by both gram negative and gram positive range of bacteria which possess antimicrobial properties and inhibitory towards sensitive strains. Bacterocins are safer than antibiotic. They can be used...
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RECENT DEVELOPMENTS IN THE TREATMENT OF SCALP PSORIASIS: A REVIEW
Psoriasis a kind of skin condition which is said to be a type of autoimmune disease making the epidermal layer of skin to deteriorate and cause severe itching, form plaques, red scaling, papules. It can be due to the genetic predisposition as the affected genes get involved in the control of the immune system. Psoriasis generally doesn’t have a specific site, it occurs anywhere on the body inclu...
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SYNTHESIS AND BIOLOGICAL SIGNIFICANCES OF 1, 2, 4-TRIAZOLE AND ITS DERIVATIVES: A REVIEW
In the last few decades, to synthesize the different new heterocyclic compounds along their derivatives which were evaluated for their biological activities as antimicrobial, antiviral, antitumor, anticonvulsant, antifungal, the triazole moiety seems to be very small but in the biological profile has attracted the attention of many researchers to explore this skeleton to its multiple potential aga...
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DEVELOPMENT OF VALIDATED HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF FEXOFENADINE HYDROCHLORIDE AND MONTELUKAST SODIUM IN TABLET DOSAGE FORM
A simple, fast and precise reverse phase high performance liquid chromatographic method has been developed for the simultaneous determination of Fexofenadine hydrochloride (FEXO) and Montelukast Sodium (MONT). Efficient chromatographic separation was achieved on phenomenex C18 column (150mm x 4.6 mm, 5 μm) as stationary phase with a mobile phase comprising of 0.5% Orthophosphoric acid pH adju...
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WHEN HEALTH POLICIES AND PROFESSIONALS’ NEEDS COLLIDE: A QUESTIONNAIRE-BASED STUDY ON PHARMACY TECHNICIANS IN EGYPT
Introduction: Expanding technicians’ role allows pharmacists to focus on patient care. In Egypt, the health authorities refuse to admit technicians’ role. In the draft amendments to the law, the “technician” was removed from the pharmacy workforce. Despite the high pharmacist density; technicians manage shifts alone. Technicians’ role is unclear and they have no educational programs resu...
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