Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
COMPARATIVE US0E OF DIFFERENT ANTIHYPERTENSIVE COMBINATIONS AT SAVAR AREA, DHAKA, BANGLADESH
Antihypertensive agents are class of drugs that are used to treat hypertension (high blood pressure) as well as other CVS disorders. Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischemic heart disease by 21%, an...
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FORMULATION AND IN-VITRO OPTIMIZATION OF EXTENDED RELEASE TABLETS OF PRAMIPEXOLE DIHYDROCHLORIDE MONOHYDRATE FOR PARKINSON’S DISEASE
The main aim of the extended release tablets is to reduce the dose frequency and to improve the patient compliance. The objective of the present study was to formulate and optimize the extended release tablets of Pramipexole dihydrochloride monohydrate for 24hrs, which made the advantage of this formulation as once daily with more patient compliance. The combination of different hydrophilic polyme...
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ANTIDEPRESSANT ACTIVITY OF DURENTA REPENS LINN.
The pet ether and chloroform extracts of Durenta repens leaves was screened for antidepressant action in tail suspension model. Both the extracts showed antidepressant action at the dose of 200mg/kg. Chloroform extract produced significant (p<0.001) mobilisation of the animals when compared with that of the standard drug Imipramine (10mg/kg) and acts as a potent centrally acting antidepressant ...
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APPLICATION OF SURFACE RESPONSE METHODOLOGY FOR SPRAY DRIED- FLUID BED PROCESSED TECHNOLOGY OF MOUTH DISSOLVING PLATFORM FOR SILDENAFIL CITRATE IN PULMONARY HYPERTENSION
Now day’s formulation research is breaking barriers of conventional methods. Today, active ingredients can be delivered with a level of convenience, performance and bioavailability never seen in the market place. Fast disintegrating or Mouth dissolving tablet (MDTs) is one such novel approach to increase consumer acceptance by virtue of rapid disintegration, self-administration without water or ...
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SYNERGISM BETWEEN CASSIA FISTULA AND FLUCONAZOLE; “A NEW APPROACH AGAINST CANDIDIASIS”
Natural products have great potential against microbes and can be used to overcome the problem of drug resistant pathogens. They are helpful in reducing the toxicity of existing antifungal compounds. This present in vitro study demonstrated the synergistic effectiveness of Cassia fistula (CF) leaves extracts and fluconazole (Flu) against isolated Flu resistant strains (FRSs) of Candida albicans (C...
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CIGARETTE SMOKE EXTRACTS INDUCE AND REPRESS GENES IN HUMAN EMBRYONIC LUNG CELLS
Disastrous effects of tobacco consumption on health remain in the focus of preclinical and clinical research. Exposures to tobacco smoke are closely connected to acute and chronic smoke lung dysfunctions and the effects are not restricted to airway inflammation processes. The facts that smoke exposure result in aberrant gene expression and changes in cellular phenotype resulting in clinical patter...
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ANTIPYRETIC ACTIVITY OF THESPESIA POPULNEA FRUITS
In the present study, the alcoholic and aqueous extracts of Thespesia populnea were investigated for their antipyretic activity. Suspension of subcutaneous administration of brewer’s yeast in albino rat leads to pyrexia. Oral administration of extracts at a dose of 500 mg/kg body weight significantly reduced the elevated body temperature of rat. This antipyretic effect has been compared with ant...
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ROLE OF INTERFERONS IN CLINICAL PRACTICE
Interferons were the first cytokines to be used therapeutically as naturally derived and as recombinant forms in humans. Their broad biological activity has resulted in clinical benefits in diseases ranging from infectious (such as viral hepatitis), autoimmune (in particular multiple sclerosis) to neoplastic (lymphomas and carcinomas). Since Interferons enhance the immune system in many ways, they...
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A STUDY ON FEASIBILITY OF OPTIMIZATION TECHNIQUE IN FORMULATION OF DISPERSIBLE TABLETS BY FACTORIAL DESIGN
In the present research work an attempt was made to study the effect of formulation variables in the development of dispersible tablet by using various super disintegrants. Instead of normal trial and error method an optimization technique was adapted. Amount of Crosscarmellose sodium, SSG and MCC were included as independent variables and hardness, percentage friability, disintegration time and w...
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PATIENT- REPORTED ADVERSE EFFECTS TO ANTI RETROVIRAL DRUGS IN A SPECIALIST HOSPITAL, NORTH WEST NIGERIA
Patients experiencing adverse effects are less likely than those not experiencing it to adhere to treatment. However little is known about the adverse drug reactions to many HIV programme in developing countries, indicating the need for Antiretroviral (ART) safety surveillance. The study is a retrospective analysis of records of adverse reactions by patients initiated on ART. A total of 1870 patie...
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